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Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

1846

Name

DUSP4

Synonymous

dual specificity phosphatase 4;DUSP4;dual specificity phosphatase 4

Definition

MAP kinase phosphatase 2|VH1 homologous phosphatase 2|dual specificity protein phosphatase 4|dual specificity protein phosphatase hVH2|mitogen-activated protein kinase phosphatase 2|serine/threonine specific protein phosphatase

Position

8p12-p11

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.927C>T; p.F309F; 8:29337284-29337284

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.927C>T; p.F309F; 8:29337284-29337284

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.777C>A; p.F259L; 8:29338304-29338304

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.179A>G; p.Y60C; 8:29350100-29350100

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.823C>T; p.R275C; 8:29337388-29337388

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.823C>T; p.R275C; 8:29337388-29337388

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.990C>T; p.F330F; 8:29337221-29337221

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.990C>T; p.F330F; 8:29337221-29337221

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.990C>T; p.F330F; 8:29337221-29337221

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.752A>C; p.H251P; 8:29338329-29338329

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1138A>T; p.S380C; 8:29337073-29337073

 breastcarcinoma; ductal_carcinomaSubstitution - Missense

c.656C>T; p.A219V; 8:29338425-29338425

 skinmalignant_melanomaSubstitution - Missense

c.1138A>T; p.S380C; 8:29337073-29337073

 breastcarcinomaSubstitution - Missense

c.1138A>T; p.S380C; 8:29337073-29337073

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; hairy_cell_leukaemiaSubstitution - Missense

c.1138A>T; p.S380C; 8:29337073-29337073

 breastcarcinomaSubstitution - Missense

c.654C>T; p.D218D; 8:29338427-29338427

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.719A>T; p.Y240F; 8:29338362-29338362

 breastcarcinomaSubstitution - Missense

c.1052G>T; p.R351L; 8:29337159-29337159

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.800-1G>A; p.?; 8:29337412-29337412

 breastcarcinomaUnknown

c.97A>G; p.S33G; 8:29350182-29350182

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1092C>T; p.F364F; 8:29337119-29337119

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1092C>T; p.F364F; 8:29337119-29337119

 skinmalignant_melanomaSubstitution - coding silent

c.1092C>T; p.F364F; 8:29337119-29337119

 skinmalignant_melanomaSubstitution - coding silent

c.1092C>T; p.F364F; 8:29337119-29337119

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.846G>T; p.A282A; 8:29337365-29337365

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.803C>T; p.A268V; 8:29337408-29337408

 skinmalignant_melanomaSubstitution - Missense

c.1013C>T; p.S338F; 8:29337198-29337198

 skinmalignant_melanomaSubstitution - Missense

c.799G>A; p.D267N; 8:29338282-29338282

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.855G>A; p.S285S; 8:29337356-29337356

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.855G>A; p.S285S; 8:29337356-29337356

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.489_490CC>TT; p.(=); 8:29340187-29340188

 skin; head_neckcarcinoma; squamous_cell_carcinomaUnknown

c.854C>T; p.S285L; 8:29337357-29337357

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.854C>T; p.S285L; 8:29337357-29337357

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.662G>T; p.G221V; 8:29338419-29338419

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.655G>A; p.A219T; 8:29338426-29338426

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.975G>A; p.G325G; 8:29337236-29337236

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.816C>T; p.C272C; 8:29337395-29337395

 skinmalignant_melanomaSubstitution - coding silent

c.945C>A; p.S315R; 8:29337266-29337266

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.804C>T; p.A268A; 8:29337407-29337407

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.476C>G; p.S159C; 8:29340201-29340201

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.945C>T; p.S315S; 8:29337266-29337266

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.842A>G; p.Q281R; 8:29337369-29337369

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.842A>G; p.Q281R; 8:29337369-29337369

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.1145C>T; p.P382L; 8:29337066-29337066

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1145C>T; p.P382L; 8:29337066-29337066

 upper_aerodigestive_tract; mouthcarcinomaSubstitution - Missense

c.690G>A; p.S230S; 8:29338391-29338391

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.921C>T; p.F307F; 8:29337290-29337290

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.538G>T; p.D180Y; 8:29340139-29340139

 lungcarcinoma; non_small_cell_carcinomaSubstitution - Missense

c.1113C>T; p.S371S; 8:29337098-29337098

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.62G>A; p.R21Q; 8:29350217-29350217

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.689C>T; p.S230L; 8:29338392-29338392

 skinmalignant_melanomaSubstitution - Missense

c.130A>G; p.K44E; 8:29350149-29350149

 haematopoietic_and_lymphoid_tissue; abdomenlymphoid_neoplasm; follicular_lymphomaSubstitution - Missense

c.584_585insG; p.P196fs*42; 8:29338496-29338497

 large_intestine; coloncarcinoma; adenocarcinomaInsertion - Frameshift

c.130A>G; p.K44E; 8:29350149-29350149

 haematopoietic_and_lymphoid_tissue; lymph_nodelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.799+1delG; p.?; 8:29338281-29338281

 livercarcinomaUnknown

c.615C>T; p.L205L; 8:29338466-29338466

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1080delC; p.T361fs*>34; 8:29337131-29337131

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1077C>A; p.T359T; 8:29337134-29337134

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1184A>G; p.*395W; 8:29337027-29337027

 livercarcinomaNonstop extension

c.522T>C; p.S174S; 8:29340155-29340155

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.732C>T; p.C244C; 8:29338349-29338349

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - coding silent

c.453C>A; p.S151S; 8:29340224-29340224

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.89G>A; p.G30D; 8:29350190-29350190

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.466G>T; p.E156*; 8:29340211-29340211

 large_intestinecarcinoma; adenocarcinomaSubstitution - Nonsense

c.856C>T; p.R286W; 8:29337355-29337355

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.458A>G; p.E153G; 8:29340219-29340219

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1047C>A; p.P349P; 8:29337164-29337164

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.316A>G; p.I106V; 8:29349963-29349963

 skinmalignant_melanomaSubstitution - Missense

c.474T>C; p.C158C; 8:29340203-29340203

 livercarcinomaSubstitution - coding silent

c.474T>C; p.C158C; 8:29340203-29340203

 livercarcinomaSubstitution - coding silent

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