Entrez Gene

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Basic Information
Gene ID	9448
Name	MAP4K4
Synonymous	mitogen-activated protein kinase kinase kinase kinase 4;MAP4K4;mitogen-activated protein kinase kinase kinase kinase 4
Definition	HPK/GCK-like kinase HGK\|MAPK/ERK kinase kinase kinase 4\|MEK kinase kinase 4\|Ste20 group protein kinase HGK\|epididymis secretory protein Li 31\|hepatocyte progenitor kinase-like/germinal center kinase-like kinase\|nck-interacting kinase
Position	2q11.2-q12
Gene Type	protein-coding
Gene Interactions:	Physical Interaction Metabolic Interaction Signaling Interaction

Interaction Type	Interactor	Data Source
Physical Interaction [Top]
interacts with	BRCA1	BIOGRID;
interacts with	CASP8	HPRD;
interacts with	DOK1	HPRD;
interacts with	GBP3	BIOGRID;
interacts with	GBP3	HPRD;
interacts with	HIST2H2BE	BIOGRID;
interacts with	HIST2H2BE	INTACT;
interacts with	ITGB1	BIOGRID;
interacts with	ITGB1	HPRD;
interacts with	KIF26B	BIOGRID;
interacts with	KIF26B	INTACT;
interacts with	KIF5A	BIOGRID;
interacts with	KIF5A	INTACT;
interacts with	MAP3K1	BIOGRID;
interacts with	MAP3K7	BIOGRID;
interacts with	MAP3K7	HPRD;
interacts with	NCK1	BIOGRID;
interacts with	NCK1	HPRD;
interacts with	PRKCE	BIOGRID;
interacts with	PRKCE	INTACT;
interacts with	RAP2A	HPRD;
interacts with	RASA1	BIOGRID;
interacts with	RASA1	HPRD;
interacts with	SLC9A1	BIOGRID;
interacts with	SLC9A1	HPRD;
interacts with	SLC9A1	INTACT;
interacts with	ZRANB1	BIOGRID;

Interaction Type	Interactor	Data Source
Metabolic Interaction [Top]
metabolic catalysis	TP53	NCI_NATURE;

Interaction Type	Interactor	Data Source
Signaling Interaction [Top]
state change	BIRC3	NCI_NATURE;
state change	CRADD	NCI_NATURE;
state change	EFNB1	NCI_NATURE;
state change	MADD	NCI_NATURE;
state change	NCK1	NCI_NATURE;
state change	RIPK1	NCI_NATURE;
state change	TNF	NCI_NATURE;
state change	TNFRSF1A	NCI_NATURE;
state change	TRADD	NCI_NATURE;
state change	TRAF2	NCI_NATURE;

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