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Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

7150

Name

TOP1

Synonymous

topoisomerase (DNA) I;TOP1;topoisomerase (DNA) I

Definition

DNA topoisomerase 1|type I DNA topoisomerase

Position

20q12-q13.1

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

interacts with

 AARS2MINT;

interacts with

 AASSMINT;

interacts with

 ABF2BIOGRID;

interacts with

 ABL1MINT;

interacts with

 ACAD9MINT;

interacts with

 ACADVLMINT;

interacts with

 ACO1BIOGRID;

interacts with

 ACO1MINT;

interacts with

 ACOT9MINT;

interacts with

 ADCK3MINT;

interacts with

 AFG3L2MINT;

interacts with

 AGKMINT;

interacts with

 AIFM1MINT;

interacts with

 AIM13BIOGRID;

interacts with

 AIM13MINT;

interacts with

 AIM26MINT;

interacts with

 ALDH18A1MINT;

interacts with

 ALDH1B1MINT;

interacts with

 ALDH1L2MINT;

interacts with

 ALDH2MINT;

interacts with

 AP2M1MINT;

interacts with

 APC9MINT;

interacts with

 APJ1INTACT;

interacts with

 APLFMINT;

interacts with

 ARHPRD;

interacts with

 ATAD3AMINT;

interacts with

 ATAD3BMINT;

interacts with

 ATP5A1MINT;

interacts with

 ATP5BMINT;

interacts with

 ATP5C1MINT;

interacts with

 ATP5F1MINT;

interacts with

 ATP5HMINT;

interacts with

 ATP5LMINT;

interacts with

 BEM3MINT;

interacts with

 BTBD1BIOGRID;

interacts with

 BTBD1HPRD;

interacts with

 BTBD2BIOGRID;

interacts with

 BTBD2HPRD;

interacts with

 C18orf55MINT;

interacts with

 C1QBPMINT;

interacts with

 C4orf14MINT;

interacts with

 C6orf203MINT;

interacts with

 C7orf30MINT;

interacts with

 CAJ1INTACT;

interacts with

 CASP3HPRD;

interacts with

 CASP6HPRD;

interacts with

 CBR1BIOGRID;

interacts with

 CBR1MINT;

interacts with

 CBX1HPRD;

interacts with

 CBX5HPRD;

interacts with

 CDK4HPRD;

interacts with

 CDKN1AHPRD;

interacts with

 CDKN2ABIOGRID;

interacts with

 CDT1BIOGRID;

interacts with

 CHCHD1MINT;

interacts with

 CLPXMINT;

interacts with

 CLU1BIOGRID;

interacts with

 CLU1MINT;

interacts with

 COX4I1MINT;

interacts with

 CPT2MINT;

interacts with

 CSNK2A1BIOGRID;

interacts with

 CSNK2A1HPRD;

interacts with

 CSNK2A2BIOGRID;

interacts with

 DAP3MINT;

interacts with

 DBTMINT;

interacts with

 DDX17HPRD;

interacts with

 DDX17INTACT;

interacts with

 DDX21HPRD;

interacts with

 DDX23HPRD;

interacts with

 DDX28MINT;

interacts with

 DDX5HPRD;

interacts with

 DEKHPRD;

interacts with

 DHX30MINT;

interacts with

 DHX9HPRD;

interacts with

 DJP1INTACT;

interacts with

 DLDMINT;

interacts with

 DNAJA3MINT;

interacts with

 DSN1BIOGRID;

interacts with

 ECH1MINT;

interacts with

 ECI1MINT;

interacts with

 ECM10INTACT;

interacts with

 EFTUD2HPRD;

interacts with

 ELAVL1HPRD;

interacts with

 ERAL1MINT;

interacts with

 ERLIN2MINT;

interacts with

 ETFAMINT;

interacts with

 FARS2MINT;

interacts with

 FASTKD1MINT;

interacts with

 FASTKD2MINT;

interacts with

 FBLHPRD;

interacts with

 FLAD1MINT;

interacts with

 FMP27MINT;

interacts with

 FOB1BIOGRID;

interacts with

 FSHRHPRD;

interacts with

 GADD45GIP1MINT;

interacts with

 GIS2BIOGRID;

interacts with

 GLDCMINT;

interacts with

 GLUD1MINT;

interacts with

 GRPEL1MINT;

interacts with

 GTPBP10MINT;

interacts with

 H1FXHPRD;

interacts with

 H2AFXHPRD;

interacts with

 H2AFYBIOGRID;

interacts with

 H2AFYHPRD;

interacts with

 HADHAMINT;

interacts with

 HARS2MINT;

interacts with

 HIST1H1AHPRD;

interacts with

 HIST1H2BCHPRD;

interacts with

 HK1MINT;

interacts with

 HNRNPA1HPRD;

interacts with

 HNRNPA2B1HPRD;

interacts with

 HNRNPA3HPRD;

interacts with

 HNRNPCHPRD;

interacts with

 HNRNPLHPRD;

interacts with

 HNRNPRHPRD;

interacts with

 HNRNPUHPRD;

interacts with

 HNRPDLMINT;

interacts with

 HP1BP3HPRD;

interacts with

 HSD17B10MINT;

interacts with

 HSP12INTACT;

interacts with

 HSP31INTACT;

interacts with

 HSP78INTACT;

interacts with

 HSP82INTACT;

interacts with

 HSPA5HPRD;

interacts with

 HSPA6HPRD;

interacts with

 HSPA9MINT;

interacts with

 HSPD1MINT;

interacts with

 HTA1BIOGRID;

interacts with

 HTA2BIOGRID;

interacts with

 HTB2BIOGRID;

interacts with

 HTB2MINT;

interacts with

 ICT1MINT;

interacts with

 IGF2BP2MINT;

interacts with

 IRA1MINT;

interacts with

 ISCA1MINT;

interacts with

 ISW1BIOGRID;

interacts with

 ISW1MINT;

interacts with

 JID1INTACT;

interacts with

 JJJ3INTACT;

interacts with

 JUNHPRD;

interacts with

 KARSMINT;

interacts with

 KIAA0391MINT;

interacts with

 LETM1MINT;

interacts with

 LIG3MINT;

interacts with

 LONP1MINT;

interacts with

 LRPPRCMINT;

interacts with

 LRS4BIOGRID;

interacts with

 MATA2MINT;

interacts with

 MCATMINT;

interacts with

 MCCC2MINT;

interacts with

 MCM4BIOGRID;

interacts with

 MCUMINT;

interacts with

 MDM36MINT;

interacts with

 ME2MINT;

interacts with

 METTL17MINT;

interacts with

 MID1MINT;

interacts with

 MKI67HPRD;

interacts with

 MMABMINT;

interacts with

 MOV10MINT;

interacts with

 MRM1MINT;

interacts with

 MRPL10MINT;

interacts with

 MRPL11MINT;

interacts with

 MRPL12MINT;

interacts with

 MRPL13MINT;

interacts with

 MRPL14MINT;

interacts with

 MRPL15MINT;

interacts with

 MRPL16MINT;

interacts with

 MRPL17MINT;

interacts with

 MRPL18MINT;

interacts with

 MRPL19MINT;

interacts with

 MRPL1MINT;

interacts with

 MRPL20MINT;

interacts with

 MRPL21MINT;

interacts with

 MRPL22MINT;

interacts with

 MRPL24MINT;

interacts with

 MRPL27MINT;

interacts with

 MRPL28MINT;

interacts with

 MRPL2MINT;

interacts with

 MRPL32MINT;

interacts with

 MRPL37MINT;

interacts with

 MRPL3MINT;

interacts with

 MRPL40MINT;

interacts with

 MRPL41MINT;

interacts with

 MRPL43MINT;

interacts with

 MRPL44MINT;

interacts with

 MRPL46MINT;

interacts with

 MRPL47MINT;

interacts with

 MRPL48MINT;

interacts with

 MRPL49MINT;

interacts with

 MRPL4MINT;

interacts with

 MRPL50MINT;

interacts with

 MRPL51MINT;

interacts with

 MRPL54MINT;

interacts with

 MRPL55MINT;

interacts with

 MRPL9MINT;

interacts with

 MRPS10MINT;

interacts with

 MRPS11MINT;

interacts with

 MRPS14MINT;

interacts with

 MRPS15MINT;

interacts with

 MRPS16MINT;

interacts with

 MRPS17MINT;

interacts with

 MRPS18AMINT;

interacts with

 MRPS18BMINT;

interacts with

 MRPS21MINT;

interacts with

 MRPS22MINT;

interacts with

 MRPS23MINT;

interacts with

 MRPS24MINT;

interacts with

 MRPS25MINT;

interacts with

 MRPS26MINT;

interacts with

 MRPS27MINT;

interacts with

 MRPS28MINT;

interacts with

 MRPS2MINT;

interacts with

 MRPS30MINT;

interacts with

 MRPS34MINT;

interacts with

 MRPS35MINT;

interacts with

 MRPS5MINT;

interacts with

 MRPS6MINT;

interacts with

 MRPS7MINT;

interacts with

 MRPS9MINT;

interacts with

 MRRFMINT;

interacts with

 MT-CO2MINT;

interacts with

 MTERFD1MINT;

interacts with

 MTERFMINT;

interacts with

 MTG1MINT;

interacts with

 MTPAPMINT;

interacts with

 MUTMINT;

interacts with

 NAB2BIOGRID;

interacts with

 NCLBIOGRID;

interacts with

 NCLMINT;

interacts with

 NCOA6HPRD;

interacts with

 NDUFA9MINT;

interacts with

 NDUFAF3MINT;

interacts with

 NDUFS1MINT;

interacts with

 NDUFS2MINT;

interacts with

 NDUFS3MINT;

interacts with

 NDUFS8MINT;

interacts with

 NDUFV1MINT;

interacts with

 NGRNMINT;

interacts with

 NME4MINT;

interacts with

 NNK1BIOGRID;

interacts with

 NOLC1HPRD;

interacts with

 NONOHPRD;

interacts with

 NOP2HPRD;

interacts with

 NSR1BIOGRID;

interacts with

 NSUN4MINT;

interacts with

 NUP42MINT;

interacts with

 OATMINT;

interacts with

 OCA1MINT;

interacts with

 PARP1HPRD;

interacts with

 PARP1INTACT;

interacts with

 PARP1MINT;

interacts with

 PARS2MINT;

interacts with

 PAWRHPRD;

interacts with

 PCCBMINT;

interacts with

 PCNAHPRD;

interacts with

 PDK3MINT;

interacts with

 PEO1MINT;

interacts with

 PHB2MINT;

interacts with

 PHBMINT;

interacts with

 PIAS1HPRD;

interacts with

 PMPCAMINT;

interacts with

 PMPCBMINT;

interacts with

 PMS1BIOGRID;

interacts with

 PNPT1MINT;

interacts with

 POB3BIOGRID;

interacts with

 POB3MINT;

interacts with

 POLDIP2MINT;

interacts with

 POLR2AHPRD;

interacts with

 POLRMTMINT;

interacts with

 PRDX4MINT;

interacts with

 PRDX5MINT;

interacts with

 PRKDCHPRD;

interacts with

 PRKDCMINT;

interacts with

 PRMT5HPRD;

interacts with

 PRPF8HPRD;

interacts with

 PTCD1MINT;

interacts with

 PTCD3MINT;

interacts with

 PUS1MINT;

interacts with

 PUSL1MINT;

interacts with

 PYCR2MINT;

interacts with

 RANHPRD;

interacts with

 RARS2MINT;

interacts with

 RBFAMINT;

interacts with

 RCC1HPRD;

interacts with

 REB1BIOGRID;

interacts with

 REB1MINT;

interacts with

 RECQLMINT;

interacts with

 REV1MINT;

interacts with

 RG9MTD1MINT;

interacts with

 RIF2MINT;

interacts with

 RLP24BIOGRID;

interacts with

 RNMTL1MINT;

interacts with

 RPA1HPRD;

interacts with

 RPA1MINT;

interacts with

 RPA34BIOGRID;

interacts with

 RPC82BIOGRID;

interacts with

 RPC82MINT;

interacts with

 RPD3BIOGRID;

interacts with

 RPD3MINT;

interacts with

 RPUSD3MINT;

interacts with

 RPUSD4MINT;

interacts with

 RRP1BBIOGRID;

interacts with

 SARS2MINT;

interacts with

 SEC20MINT;

interacts with

 SF3B1HPRD;

interacts with

 SF3B3HPRD;

interacts with

 SFPQBIOGRID;

interacts with

 SFPQHPRD;

interacts with

 SFXN1MINT;

interacts with

 SHMT2MINT;

interacts with

 SIS1INTACT;

interacts with

 SLC25A10MINT;

interacts with

 SLC25A11MINT;

interacts with

 SLC25A12MINT;

interacts with

 SLC25A13MINT;

interacts with

 SLC25A18MINT;

interacts with

 SLC25A1MINT;

interacts with

 SLC25A4MINT;

interacts with

 SLC25A5MINT;

interacts with

 SLD5BIOGRID;

interacts with

 SLIRPMINT;

interacts with

 SML1BIOGRID;

interacts with

 SML1MINT;

interacts with

 SMT3BIOGRID;

interacts with

 SNRNP200HPRD;

interacts with

 SNRPA1HPRD;

interacts with

 SPT16BIOGRID;

interacts with

 SPT16MINT;

interacts with

 SRSF11BIOGRID;

interacts with

 SRSF11HPRD;

interacts with

 SRSF1BIOGRID;

interacts with

 SRSF1HPRD;

interacts with

 SSA1BIOGRID;

interacts with

 SSA1INTACT;

interacts with

 SSA2BIOGRID;

interacts with

 SSA2INTACT;

interacts with

 SSB1BIOGRID;

interacts with

 SSB1INTACT;

interacts with

 SSB2BIOGRID;

interacts with

 SSB2INTACT;

interacts with

 SSBP1MINT;

interacts with

 SSC1INTACT;

interacts with

 SSE1INTACT;

interacts with

 SSZ1INTACT;

interacts with

 STOML2MINT;

interacts with

 SUCLA2MINT;

interacts with

 SUPT16HINTACT;

interacts with

 SUPV3L1MINT;

interacts with

 SWA2INTACT;

interacts with

 TAL1BIOGRID;

interacts with

 TARS2MINT;

interacts with

 TCO89MINT;

interacts with

 TCOF1HPRD;

interacts with

 TEFMMINT;

interacts with

 TFAMMINT;

interacts with

 TFB1MMINT;

interacts with

 TIF4631BIOGRID;

interacts with

 TIF4631MINT;

interacts with

 TIR4BIOGRID;

interacts with

 TIR4MINT;

interacts with

 TMPOINTACT;

interacts with

 TOF1BIOGRID;

interacts with

 TOF2BIOGRID;

interacts with

 TOP2AHPRD;

interacts with

 TOPBP1MINT;

interacts with

 TOPORSBIOGRID;

interacts with

 TOPORSHPRD;

interacts with

 TP53BIOGRID;

interacts with

 TRI1BIOGRID;

interacts with

 TRI1MINT;

interacts with

 TRUB2MINT;

interacts with

 UBE2IBIOGRID;

interacts with

 UBE2IHPRD;

interacts with

 UBP14BIOGRID;

interacts with

 UBP14MINT;

interacts with

 UQCRC1MINT;

interacts with

 UQCRC2MINT;

interacts with

 UQCRFS1MINT;

interacts with

 VARS2MINT;

interacts with

 VDAC1MINT;

interacts with

 VDAC3MINT;

interacts with

 WBSCR16MINT;

interacts with

 WDR77HPRD;

interacts with

 WRNINTACT;

interacts with

 XRCC1MINT;

interacts with

 XRCC5HPRD;

interacts with

 XRCC5INTACT;

interacts with

 XRCC5MINT;

interacts with

 XRCC6HPRD;

interacts with

 XRCC6INTACT;

interacts with

 XRCC6MINT;

interacts with

 YARS2MINT;

interacts with

 YDJ1BIOGRID;

interacts with

 YDJ1INTACT;

interacts with

 YME1L1MINT;

interacts with

 YTA7BIOGRID;

interacts with

 ZAP1MINT;

interacts with

 ZIM17MINT;

Metabolic Interaction   [Top]

There is no record for TOP1

Signaling Interaction   [Top]

There is no record for TOP1


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