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Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

4092

Name

SMAD7

Synonymous

SMAD family member 7;SMAD7;SMAD family member 7

Definition

MAD (mothers against decapentaplegic, Drosophila) homolog 7|MAD homolog 8|Mothers against decapentaplegic, drosophila, homolog of, 7|SMAD, mothers against DPP homolog 7|hSMAD7|mothers against DPP homolog 8|mothers against decapentaplegic homolog 7

Position

18q21.1

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

 AXIN1NCI_NATURE;

in same component

 BMPR2NCI_NATURE;

in same component

 CAV1NCI_NATURE;

in same component

 HDAC1NCI_NATURE;

in same component

 NEDD4LNCI_NATURE;

in same component

 PPP1CANCI_NATURE;

in same component

 PPP1R15ANCI_NATURE;

in same component

 RNF111NCI_NATURE;

in same component

 SMURF1CELL_MAP;

in same component

 SMURF1NCI_NATURE;

in same component

 SMURF2CELL_MAP;

in same component

 STRAPNCI_NATURE;

in same component

 TGFBR1NCI_NATURE;

in same component

 TGFBR2NCI_NATURE;

in same component

 WWP1NCI_NATURE;

in same component

 YAP1NCI_NATURE;

interacts with

 ACVR1BBIOGRID;

interacts with

 ACVR1BHPRD;

interacts with

 AKT1BIOGRID;

interacts with

 AKT1HPRD;

interacts with

 ASH1LHPRD;

interacts with

 ASH1LMINT;

interacts with

 AXIN1HPRD;

interacts with

 AXIN1MINT;

interacts with

 AXIN2HPRD;

interacts with

 Axin2MINT;

interacts with

 BMPR1ABIOGRID;

interacts with

 BMPR1BHPRD;

interacts with

 COPS5INTACT;

interacts with

 CTNNB1BIOGRID;

interacts with

 CTNNB1HPRD;

interacts with

 CXXC5HPRD;

interacts with

 CXXC5MINT;

interacts with

 DVL1BIOGRID;

interacts with

 Dvl1CELL_MAP;

interacts with

 DVL1HPRD;

interacts with

 EP300BIOGRID;

interacts with

 EP300CELL_MAP;

interacts with

 EP300HPRD;

interacts with

 ERBB2IPBIOGRID;

interacts with

 ERBB2IPHPRD;

interacts with

 FKBP1ABIOGRID;

interacts with

 HAT1HPRD;

interacts with

 HDAC1BIOGRID;

interacts with

 HDAC2BIOGRID;

interacts with

 HDAC3BIOGRID;

interacts with

 HDAC5BIOGRID;

interacts with

 HDAC6BIOGRID;

interacts with

 HEYLHPRD;

interacts with

 HEYLMINT;

interacts with

 ITCHBIOGRID;

interacts with

 KAT2BBIOGRID;

interacts with

 KDM2AHPRD;

interacts with

 KDM2AMINT;

interacts with

 LEF1BIOGRID;

interacts with

 MAP2K3BIOGRID;

interacts with

 MAP2K3HPRD;

interacts with

 MAP2K6BIOGRID;

interacts with

 MAP2K6CELL_MAP;

interacts with

 MAP2K6HPRD;

interacts with

 MAP3K7BIOGRID;

interacts with

 MAP3K7CELL_MAP;

interacts with

 MAP3K7HPRD;

interacts with

 MAPK14BIOGRID;

interacts with

 MAPK14CELL_MAP;

interacts with

 MAPK14HPRD;

interacts with

 MBD1HPRD;

interacts with

 MKL2MINT;

interacts with

 MYOD1HPRD;

interacts with

 MYOD1MINT;

interacts with

 NEDD4BIOGRID;

interacts with

 PARD3BBIOGRID;

interacts with

 PIAS1HPRD;

interacts with

 PIAS1MINT;

interacts with

 PIAS4BIOGRID;

interacts with

 PIAS4HPRD;

interacts with

 PIAS4MINT;

interacts with

 PKHD1HPRD;

interacts with

 RNF111BIOGRID;

interacts with

 RNF111HPRD;

interacts with

 Rnf111MINT;

interacts with

 SASH3HPRD;

interacts with

 Sash3MINT;

interacts with

 SIRT1BIOGRID;

interacts with

 SMAD2BIOGRID;

interacts with

 SMAD4BIOGRID;

interacts with

 SMAD6BIOGRID;

interacts with

 SMAD6HPRD;

interacts with

 SMURF1BIOGRID;

interacts with

 SMURF1CELL_MAP;

interacts with

 SMURF1HPRD;

interacts with

 SMURF2BIOGRID;

interacts with

 SMURF2CELL_MAP;

interacts with

 SMURF2HPRD;

interacts with

 SMURF2MINT;

interacts with

 SOX13HPRD;

interacts with

 SOX13MINT;

interacts with

 SOX5HPRD;

interacts with

 SOX5MINT;

interacts with

 SOX7HPRD;

interacts with

 SOX7MINT;

interacts with

 SRFBIOGRID;

interacts with

 STAMBPL1CELL_MAP;

interacts with

 STAMBPL1HPRD;

interacts with

 STAMBPBIOGRID;

interacts with

 STAMBPHPRD;

interacts with

 STRAPBIOGRID;

interacts with

 STRAPCELL_MAP;

interacts with

 STRAPHPRD;

interacts with

 TAB1BIOGRID;

interacts with

 TGFBR1BIOGRID;

interacts with

 TGFBR2BIOGRID;

interacts with

 TGFBR2CELL_MAP;

interacts with

 TGFBR2HPRD;

interacts with

 TTF1HPRD;

interacts with

 TTF1MINT;

interacts with

 TTF2HPRD;

interacts with

 TTF2MINT;

interacts with

 Uba52MINT;

interacts with

 UCHL5BIOGRID;

interacts with

 WISP1HPRD;

interacts with

 WWP1BIOGRID;

interacts with

 Wwp2BIOGRID;

interacts with

 WWP2INTACT;

interacts with

 XRCC6HPRD;

interacts with

 XRCC6MINT;

interacts with

 YAP1BIOGRID;

interacts with

 YAP1HPRD;

interacts with

 ZBTB11HPRD;

interacts with

 ZBTB11MINT;

interacts with

 ZBTB44HPRD;

interacts with

 ZEB1BIOGRID;

interacts with

 ZNF107HPRD;

interacts with

 ZNF107MINT;

Metabolic Interaction   [Top]

Interaction Type

Interactor

Data Source

metabolic catalysis

 FOSNCI_NATURE;

metabolic catalysis

 JUNNCI_NATURE;

metabolic catalysis

 SMAD4NCI_NATURE;

metabolic catalysis

 SP1NCI_NATURE;

metabolic catalysis

 STAT1NCI_NATURE;

metabolic catalysis

 TFE3NCI_NATURE;

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

 AXIN1NCI_NATURE;

reacts with

 BMPR2NCI_NATURE;

reacts with

 CAV1NCI_NATURE;

reacts with

 HDAC1NCI_NATURE;

reacts with

 NEDD4LNCI_NATURE;

reacts with

 PPP1CANCI_NATURE;

reacts with

 PPP1R15ANCI_NATURE;

reacts with

 RNF111NCI_NATURE;

reacts with

 SMAD1NCI_NATURE;

reacts with

 SMAD7CELL_MAP;

reacts with

 SMAD7NCI_NATURE;

reacts with

 SMURF1CELL_MAP;

reacts with

 SMURF1NCI_NATURE;

reacts with

 SMURF2CELL_MAP;

reacts with

 STRAPNCI_NATURE;

reacts with

 TGFBR1NCI_NATURE;

reacts with

 TGFBR2NCI_NATURE;

reacts with

 WWP1NCI_NATURE;

reacts with

 YAP1NCI_NATURE;

reacts with

 ZFYVE9NCI_NATURE;

state change

 FKBP1ANCI_NATURE;

state change

 PDPK1NCI_NATURE;

state change

 SMURF1CELL_MAP;

state change

 SMURF1NCI_NATURE;

state change

 TGFBR1NCI_NATURE;

state change

 TGFBR2NCI_NATURE;

state change

 ZFYVE9NCI_NATURE;

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