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Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

4086

Name

SMAD1

Synonymous

SMAD family member 1;SMAD1;SMAD family member 1

Definition

MAD homolog 1|MAD, mothers against decapentaplegic homolog 1|Mad-related protein 1|SMAD, mothers against DPP homolog 1|TGF-beta signaling protein 1|mothers against DPP homolog 1|mothers against decapentaplegic homolog 1|transforming growth factor-beta sig

Position

4q31

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

 SKINCI_NATURE;

in same component

 SMAD4NCI_NATURE;

in same component

 SMAD6NCI_NATURE;

in same component

 SMURF1NCI_NATURE;

in same component

 SMURF2NCI_NATURE;

in same component

 ZFYVE16NCI_NATURE;

interacts with

 ACVR1BIOGRID;

interacts with

 ACVR1HPRD;

interacts with

 AKR1B1HPRD;

interacts with

 AKR1B1MINT;

interacts with

 ANKRD27HPRD;

interacts with

 ANKRD27MINT;

interacts with

 AP2A2HPRD;

interacts with

 AP2A2MINT;

interacts with

 ARHGEF6HPRD;

interacts with

 ARL4DHPRD;

interacts with

 ARHPRD;

interacts with

 ARMINT;

interacts with

 BMPR1AHPRD;

interacts with

 BTBD2HPRD;

interacts with

 BTG2HPRD;

interacts with

 CAMSAP1MINT;

interacts with

 COL4A1HPRD;

interacts with

 CREBBPBIOGRID;

interacts with

 CREBBPHPRD;

interacts with

 DVL1BIOGRID;

interacts with

 ECSITHPRD;

interacts with

 EIF2AK4HPRD;

interacts with

 ELP3HPRD;

interacts with

 EP300BIOGRID;

interacts with

 EP300HPRD;

interacts with

 ERBB2IPBIOGRID;

interacts with

 ERBB2IPHPRD;

interacts with

 FBXL12HPRD;

interacts with

 Fbxl12MINT;

interacts with

 FBXO30HPRD;

interacts with

 Fbxo30MINT;

interacts with

 FHL5HPRD;

interacts with

 Fhl5MINT;

interacts with

 FOXG1BIOGRID;

interacts with

 FOXG1HPRD;

interacts with

 FOXO3BIOGRID;

interacts with

 GDF6HPRD;

interacts with

 GLI3HPRD;

interacts with

 GMEB1HPRD;

interacts with

 GMEB1MINT;

interacts with

 GSCHPRD;

interacts with

 HBP1HPRD;

interacts with

 HBP1MINT;

interacts with

 HDAC1BIOGRID;

interacts with

 HIPK2BIOGRID;

interacts with

 HIPK2HPRD;

interacts with

 HMGA2BIOGRID;

interacts with

 HOXA13HPRD;

interacts with

 HOXA5BIOGRID;

interacts with

 HOXC8BIOGRID;

interacts with

 HOXC8HPRD;

interacts with

 HOXD13HPRD;

interacts with

 ICKHPRD;

interacts with

 ICKMINT;

interacts with

 ING2HPRD;

interacts with

 Ing2MINT;

interacts with

 INPP4AHPRD;

interacts with

 INPP4AMINT;

interacts with

 IRF2BP1MINT;

interacts with

 KAT2ABIOGRID;

interacts with

 KAT2BHPRD;

interacts with

 KDM6BBIOGRID;

interacts with

 LEMD3HPRD;

interacts with

 LEMD3MINT;

interacts with

 MAPK1BIOGRID;

interacts with

 MAPK1HPRD;

interacts with

 MAST4MINT;

interacts with

 MBD1HPRD;

interacts with

 MECOMBIOGRID;

interacts with

 MED15BIOGRID;

interacts with

 MED15MINT;

interacts with

 MED24BIOGRID;

interacts with

 MED24MINT;

interacts with

 MED6BIOGRID;

interacts with

 MED6HPRD;

interacts with

 MED6MINT;

interacts with

 MEN1HPRD;

interacts with

 MGAMINT;

interacts with

 MKL2MINT;

interacts with

 MLL2HPRD;

interacts with

 MLL2MINT;

interacts with

 NAT9HPRD;

interacts with

 Nat9MINT;

interacts with

 NEDD4MINT;

interacts with

 NEDD9BIOGRID;

interacts with

 NEDD9HPRD;

interacts with

 NEDD9MINT;

interacts with

 NEUROG1BIOGRID;

interacts with

 NEUROG1HPRD;

interacts with

 NKX3-2BIOGRID;

interacts with

 NOTCH2HPRD;

interacts with

 NOTCH2MINT;

interacts with

 NUP214BIOGRID;

interacts with

 OAZ1BIOGRID;

interacts with

 OAZ3BIOGRID;

interacts with

 PAK1HPRD;

interacts with

 PARD3BBIOGRID;

interacts with

 PIAS1HPRD;

interacts with

 PIAS1MINT;

interacts with

 PIAS4BIOGRID;

interacts with

 PIAS4HPRD;

interacts with

 PIAS4MINT;

interacts with

 PIGQHPRD;

interacts with

 PIGQMINT;

interacts with

 PLEKHB1HPRD;

interacts with

 Plekhb1MINT;

interacts with

 PSMB4BIOGRID;

interacts with

 PSMB4HPRD;

interacts with

 PSMB4MINT;

interacts with

 PSMD11HPRD;

interacts with

 PSMD11MINT;

interacts with

 PSMD1HPRD;

interacts with

 PSMD1MINT;

interacts with

 PUM1HPRD;

interacts with

 PUM1MINT;

interacts with

 RAB30HPRD;

interacts with

 RAB34HPRD;

interacts with

 RAB38HPRD;

interacts with

 RAB3BHPRD;

interacts with

 Rab3bMINT;

interacts with

 RAB6BHPRD;

interacts with

 RAC2HPRD;

interacts with

 RANHPRD;

interacts with

 RAP2AHPRD;

interacts with

 RASD2HPRD;

interacts with

 RASL12HPRD;

interacts with

 RFX1HPRD;

interacts with

 RFX1MINT;

interacts with

 RHEBL1HPRD;

interacts with

 Rhebl1MINT;

interacts with

 RUNX2BIOGRID;

interacts with

 RUNX3BIOGRID;

interacts with

 SF3B1HPRD;

interacts with

 SF3B1MINT;

interacts with

 Sip1BIOGRID;

interacts with

 SKILHPRD;

interacts with

 SKIBIOGRID;

interacts with

 SMAD4BIOGRID;

interacts with

 SMAD4HPRD;

interacts with

 SMAD4MINT;

interacts with

 SMAD5HPRD;

interacts with

 SMAD5MINT;

interacts with

 SMAD6BIOGRID;

interacts with

 SMAD6HPRD;

interacts with

 SMARCE1HPRD;

interacts with

 SMARCE1MINT;

interacts with

 SMURF1BIOGRID;

interacts with

 SMURF1HPRD;

interacts with

 SMURF1MINT;

interacts with

 SMURF2BIOGRID;

interacts with

 SMURF2HPRD;

interacts with

 SMURF2MINT;

interacts with

 SNIP1BIOGRID;

interacts with

 SNIP1HPRD;

interacts with

 SNRNP70HPRD;

interacts with

 SNRNP70MINT;

interacts with

 SOX5HPRD;

interacts with

 SOX5MINT;

interacts with

 SQSTM1HPRD;

interacts with

 SS18L1BIOGRID;

interacts with

 STARD13HPRD;

interacts with

 STARD13MINT;

interacts with

 STAT3BIOGRID;

interacts with

 STAT3HPRD;

interacts with

 STUB1BIOGRID;

interacts with

 STUB1HPRD;

interacts with

 SUV39H1HPRD;

interacts with

 TCF20BIOGRID;

interacts with

 TGIF1BIOGRID;

interacts with

 TNNT1HPRD;

interacts with

 TOB1BIOGRID;

interacts with

 TOB1HPRD;

interacts with

 TRIP6HPRD;

interacts with

 TTF1HPRD;

interacts with

 TTF1MINT;

interacts with

 TTF2HPRD;

interacts with

 TTF2MINT;

interacts with

 TUBA4AMINT;

interacts with

 UBE2ZHPRD;

interacts with

 UBXN1HPRD;

interacts with

 Ubxn1MINT;

interacts with

 VEPH1HPRD;

interacts with

 VPS24HPRD;

interacts with

 VPS24MINT;

interacts with

 WWP1BIOGRID;

interacts with

 XPCHPRD;

interacts with

 XPCMINT;

interacts with

 XPO1HPRD;

interacts with

 YY1BIOGRID;

interacts with

 ZBTB44HPRD;

interacts with

 ZCCHC12BIOGRID;

interacts with

 ZDHHC3HPRD;

interacts with

 ZDHHC3MINT;

interacts with

 ZEB1BIOGRID;

interacts with

 ZEB2HPRD;

interacts with

 ZEB2MINT;

interacts with

 ZNF251MINT;

interacts with

 ZNF423BIOGRID;

interacts with

 ZNF423HPRD;

interacts with

 ZNF510HPRD;

interacts with

 ZNF510MINT;

interacts with

 ZNF512BMINT;

interacts with

 ZNF521HPRD;

interacts with

 ZNF76HPRD;

interacts with

 ZNF76MINT;

interacts with

 ZSCAN4HPRD;

interacts with

 ZSCAN4MINT;

Metabolic Interaction   [Top]

There is no record for SMAD1

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

 BMP7NCI_NATURE;

reacts with

 BMPR2NCI_NATURE;

reacts with

 PPP1CANCI_NATURE;

reacts with

 PPP1R15ANCI_NATURE;

reacts with

 SKINCI_NATURE;

reacts with

 SMAD1NCI_NATURE;

reacts with

 SMAD4NCI_NATURE;

reacts with

 SMAD6NCI_NATURE;

reacts with

 SMAD7NCI_NATURE;

reacts with

 SMURF1NCI_NATURE;

reacts with

 SMURF2NCI_NATURE;

reacts with

 ZFYVE16NCI_NATURE;

state change

 BMP6NCI_NATURE;

state change

 BMPR2NCI_NATURE;

state change

 MAPK1NCI_NATURE;

state change

 NUP214NCI_NATURE;

state change

 PPM1ANCI_NATURE;

state change

 SMAD1NCI_NATURE;

state change

 SMURF1NCI_NATURE;

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