| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 4086 |
Name | SMAD1 |
Synonym | BSP-1|BSP1|JV4-1|JV41|MADH1|MADR1;SMAD family member 1;SMAD1;SMAD family member 1 |
Definition | MAD homolog 1|MAD, mothers against decapentaplegic homolog 1|Mad-related protein 1|SMAD, mothers against DPP homolog 1|TGF-beta signaling protein 1|mothers against DPP homolog 1|mothers against decapentaplegic homolog 1|transforming growth factor-beta sig |
Position | 4q31 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | ctcf: first multivalent nuclear factor;PID BioCarta;100194 |
Pathway | BMP receptor signaling;PID Curated;200123 |
Pathway | alk in cardiac myocytes;PID BioCarta;100244 |
Pathway | Wnt signaling pathway;PANTHER;P00057 |
Pathway | Signaling by BMP;Reactome;REACT:12034 |
Pathway | ErbB1 downstream signaling;PID Curated;200113 |
Pathway | ALK1 signaling events;PID Curated;200126 |
Pathway | TGF-beta signaling pathway;PANTHER;P00052 |
Pathway | BMP Signalling Pathway;BioCyc;PWY66-11 |
Pathway | ALK2 signaling events;PID Curated;200138 |
Pathway | TGF-beta signaling pathway;KEGG PATHWAY;hsa04350 |
Disease | Pancreas cancer;FunDO |
Disease | Lung cancer;FunDO |
External Links | |
Links to Entrez Gene | 4086 |
Links to all GeneRIF Items | 4086 |
Links to iHOP | 4086 |
Sequence Information | |
Nucleotide Sequence | >4086 : length: 3056 GGCAGCTGAGGAGTGGAGGCTGGGCAGCTCCGACTCCCTGACGCCAGCGCGACCAGATCA ATCCAGGCTCCAGGAGAAAGCAGGCGGGCGGGCGGAGAAAGGAGAGGCCGAGCGGCTCAA CCCGGGCCGAGGCTCGGGGAGCGGAGAGTGGCGCAGCGCCCGGCCGTCCGGACCCGGGCC GCGAGACCCCGCTCGCCCGGCCACTCGTGCTCCCACACGGACGGGCGCGCCGCCAACCCG GTGCTGACTGGGTTACTTTTTTAAACACTAGGAATGGTAATTTCTACTCTTCTGGACTTC AAACTAAGAAGTTAAAGAGACTTCTCTGTAAATAAACAAATCTCTTCTGCTGTCCTTTTG CATTTGGAGACAGCTTTATTTCACCATATCCAAGGAGTATAACTAGTGCTGTCATTATGA ATGTGACAAGTTTATTTTCCTTTACAAGTCCAGCTGTGAAGAGACTTCTTGGGTGGAAAC AGGGCGATGAAGAAGAAAAATGGGCAGAGAAAGCTGTTGATGCTTTGGTGAAAAAACTGA AGAAAAAGAAAGGTGCCATGGAGGAACTGGAAAAGGCCTTGAGCTGCCCAGGGCAACCGA GTAACTGTGTCACCATTCCCCGCTCTCTGGATGGCAGGCTGCAAGTCTCCCACCGGAAGG GACTGCCTCATGTCATTTACTGCCGTGTGTGGCGCTGGCCCGATCTTCAGAGCCACCATG AACTAAAACCACTGGAATGCTGTGAGTTTCCTTTTGGTTCCAAGCAGAAGGAGGTCTGCA TCAATCCCTACCACTATAAGAGAGTAGAAAGCCCTGTACTTCCTCCTGTGCTGGTTCCAA GACACAGCGAATATAATCCTCAGCACAGCCTCTTAGCTCAGTTCCGTAACTTAGGACAAA ATGAGCCTCACATGCCACTCAACGCCACTTTTCCAGATTCTTTCCAGCAACCCAACAGCC ACCCGTTTCCTCACTCTCCCAATAGCAGTTACCCAAACTCTCCTGGGAGCAGCAGCAGCA CCTACCCTCACTCTCCCACCAGCTCAGACCCAGGAAGCCCTTTCCAGATGCCAGCTGATA CGCCCCCACCTGCTTACCTGCCTCCTGAAGACCCCATGACCCAGGATGGCTCTCAGCCGA TGGACACAAACATGATGGCGCCTCCCCTGCCCTCAGAAATCAACAGAGGAGATGTTCAGG CGGTTGCTTATGAGGAACCAAAACACTGGTGCTCTATTGTCTACTATGAGCTCAACAATC GTGTGGGTGAAGCGTTCCATGCCTCCTCCACAAGTGTGTTGGTGGATGGTTTCACTGATC CTTCCAACAATAAGAACCGTTTCTGCCTTGGGCTGCTCTCCAATGTTAACCGGAATTCCA CTATTGAAAACACCAGGCGGCATATTGGAAAAGGAGTTCATCTTTATTATGTTGGAGGGG AGGTGTATGCCGAATGCCTTAGTGACAGTAGCATCTTTGTGCAAAGTCGGAACTGCAACT ACCATCATGGATTTCATCCTACTACTGTTTGCAAGATCCCTAGTGGGTGTAGTCTGAAAA TTTTTAACAACCAAGAATTTGCTCAGTTATTGGCACAGTCTGTGAACCATGGATTTGAGA CAGTCTATGAGCTTACAAAAATGTGTACTATACGTATGAGCTTTGTGAAGGGCTGGGGAG CAGAATACCACCGCCAGGATGTTACTAGCACCCCCTGCTGGATTGAGATACATCTGCACG GCCCCCTCCAGTGGCTGGATAAAGTTCTTACTCAAATGGGTTCACCTCATAATCCTATTT CATCTGTATCTTAAATGGCCCCAGGCATCTGCCTCTGGAAAACTATTGAGCCTTGCATGT ACTTGAAGGATGGATGAGTCAGACACGATTGAGAACTGACAAAGGAGCCTTGATAATACT TGACCTCTGTGACCAACTGTTGGATTCAGAAATTTAAACAAAAAAAAAAAAAAACACACA CACCTTGGTAACATACTGTTGATATCAAGAACCTGTTTAGTTTACATTGTAACATTCTAT TGTAAAATCAACTAAAATTCAGACTTTTAGCAGGACTTTGTGTACAGTTAAAGGAGAGAT GGCCAAGCCAGGGACAAATTGTCTATTAGAAAACGGTCCTAAGAGATTCTTTGGTGTTTG GCACTTTAAGGTCATCGTTGGGCAGAAGTTTAGCATTAATAGTTGTTCTGAAACGTGTTT TATCAGGTTTAGAGCCCATGTTGAGTCTTCTTTTCATGGGTTTTCATAATATTTTAAAAC TATTTGTTTAGCGATGGTTTTGTTCGTTTAAGTAAAGGTTAATCTTGATGATATACATAA TAATCTTTCTAAAATTGTATGCTGACCATACTTGCTGTCAGAATAATGCTAGGCATATGC TTTTTGCTAAATATGTATGTACAGAGTATTTGGAAGTTAAGAATTGATTAGACTAGTGAA TTTAGGAGTATTTGAGGTGGGTGGGGGGAAGAGGGAAATGACAACTGCAAATGTAGACTA TACTGTAAAAATTCAGTTTGTTGCTTTAAAGAAACAAACTGATACCTGAATTTTGCTGTG TTTCCATTTTTTAGAGATTTTTATCATTTTTTTCTCTCTCGGCATTCTTTTTTCTCATAC TCTTCAAAAAGCAGTTCTGCAGCTGGTTAATTCATGTAACTGTGAGAGCAAATGAATAAT TCCTGCTATTCTGAAATTGCCTACATGTTTCAATACCAGTTATATGGAGTGCTTGAATTT AATAAGCAGTTTTTACGGAGTTTACAGTACAGAAATAGGCTTTAATTTTCAAGTGAATTT TTTGCCAAACTTAGTAACTCTGTTAAATATTTGGAGGATTTAAAGAACATCCCAGTTTGA ATTCATTTCAAACTTTTTAAATTTTTTTGTACTATGTTTGGTTTTATTTTCCTTCTGTTA ATCTTTTGTATTCACTTATGCTCTCGTACATTGAGTACTTTTATTCCAAAACTAGTGGGT TTTCTCTACTGGAAATTTTCAATAAACCTGTCATTATTGCTTACTTTGATTAAAAA |
Protein Sequence | >4086 : length: 465 MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPGQ PSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEV CINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQPN SHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDGSQ PMDTNMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT DPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNC NYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGW GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS |