| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3815 |
Name | KIT |
Synonymous | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog;KIT;v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
Definition | mast/stem cell growth factor receptor Kit|p145 c-kit|piebald trait protein|proto-oncogene c-Kit|proto-oncogene tyrosine-protein kinase Kit|soluble KIT variant 1|tyrosine-protein kinase Kit|v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein |
Position | 4q12 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
CBL | CELL_MAP; |
in same component |
EPO | NCI_NATURE; |
in same component |
EPOR | NCI_NATURE; |
in same component |
GAB2 | REACTOME; |
in same component |
JAK2 | REACTOME; |
in same component |
KITLG | NCI_NATURE; |
in same component |
PIK3CA | REACTOME; |
in same component |
PRKCA | REACTOME; |
in same component |
PTPN11 | REACTOME; |
in same component |
PTPN6 | REACTOME; |
in same component |
PTPRU | REACTOME; |
in same component |
SH2B2 | REACTOME; |
in same component |
SH2B3 | REACTOME; |
in same component |
SOCS1 | REACTOME; |
in same component |
SOCS6 | REACTOME; |
in same component |
SOS1 | REACTOME; |
interacts with |
Btk | CELL_MAP; |
interacts with |
BTK | HPRD; |
interacts with |
CBLB | BIOGRID; |
interacts with |
CBLB | HPRD; |
interacts with |
CBL | BIOGRID; |
interacts with |
CBL | CELL_MAP; |
interacts with |
CBL | HPRD; |
interacts with |
CBL | NCI_NATURE; |
interacts with |
CD63 | BIOGRID; |
interacts with |
CD63 | HPRD; |
interacts with |
CD81 | BIOGRID; |
interacts with |
CD81 | HPRD; |
interacts with |
CD9 | BIOGRID; |
interacts with |
CD9 | HPRD; |
interacts with |
CISH | HPRD; |
interacts with |
CLTC | BIOGRID; |
interacts with |
CLTC | HPRD; |
interacts with |
CRK | CELL_MAP; |
interacts with |
CRK | HPRD; |
interacts with |
CRK | MINT; |
interacts with |
CRKL | BIOGRID; |
interacts with |
CRKL | CELL_MAP; |
interacts with |
CRKL | HPRD; |
interacts with |
CRKL | NCI_NATURE; |
interacts with |
CSF2RA | HPRD; |
interacts with |
CSF2RB | CELL_MAP; |
interacts with |
CSF2RB | HPRD; |
interacts with |
DOK1 | BIOGRID; |
interacts with |
DOK1 | CELL_MAP; |
interacts with |
DOK1 | HPRD; |
interacts with |
EPOR | CELL_MAP; |
interacts with |
EPOR | HPRD; |
interacts with |
FYN | CELL_MAP; |
interacts with |
FYN | HPRD; |
interacts with |
GRAP2 | HPRD; |
interacts with |
GRAP | BIOGRID; |
interacts with |
GRAP | CELL_MAP; |
interacts with |
GRAP | HPRD; |
interacts with |
GRB10 | BIOGRID; |
interacts with |
GRB10 | HPRD; |
interacts with |
GRB7 | BIOGRID; |
interacts with |
GRB7 | CELL_MAP; |
interacts with |
GRB7 | HPRD; |
interacts with |
GRB7 | MINT; |
interacts with |
HCK | CELL_MAP; |
interacts with |
HCK | HPRD; |
interacts with |
INPP5D | BIOGRID; |
interacts with |
INPP5D | CELL_MAP; |
interacts with |
INPP5D | HPRD; |
interacts with |
JAK2 | BIOGRID; |
interacts with |
JAK2 | CELL_MAP; |
interacts with |
JAK2 | HPRD; |
interacts with |
KITLG | BIOGRID; |
interacts with |
KITLG | CELL_MAP; |
interacts with |
KITLG | HPRD; |
interacts with |
LCK | BIOGRID; |
interacts with |
LCK | HPRD; |
interacts with |
LYN | BIOGRID; |
interacts with |
LYN | CELL_MAP; |
interacts with |
LYN | HPRD; |
interacts with |
MATK | BIOGRID; |
interacts with |
MATK | CELL_MAP; |
interacts with |
MATK | HPRD; |
interacts with |
MPDZ | BIOGRID; |
interacts with |
Mpdz | CELL_MAP; |
interacts with |
MPDZ | HPRD; |
interacts with |
PIK3CG | CELL_MAP; |
interacts with |
PIK3R1 | BIOGRID; |
interacts with |
PIK3R1 | CELL_MAP; |
interacts with |
PIK3R1 | HPRD; |
interacts with |
PIK3R1 | MINT; |
interacts with |
PIK3R2 | BIOGRID; |
interacts with |
PIK3R2 | HPRD; |
interacts with |
PIK3R2 | MINT; |
interacts with |
PLCE1 | CELL_MAP; |
interacts with |
PLCE1 | HPRD; |
interacts with |
PLCG1 | BIOGRID; |
interacts with |
PLCG1 | CELL_MAP; |
interacts with |
PLCG1 | MINT; |
interacts with |
PRKCA | HPRD; |
interacts with |
PRKCB | HPRD; |
interacts with |
PTPN11 | BIOGRID; |
interacts with |
PTPN11 | HPRD; |
interacts with |
PTPN6 | BIOGRID; |
interacts with |
PTPN6 | HPRD; |
interacts with |
PTPRO | BIOGRID; |
interacts with |
PTPRU | CELL_MAP; |
interacts with |
PTPRU | HPRD; |
interacts with |
RASA1 | CELL_MAP; |
interacts with |
RASA1 | HPRD; |
interacts with |
RFC1 | BIOGRID; |
interacts with |
Sh2b2 | CELL_MAP; |
interacts with |
SH2B2 | HPRD; |
interacts with |
SH2B3 | HPRD; |
interacts with |
SH3KBP1 | BIOGRID; |
interacts with |
SH3KBP1 | CELL_MAP; |
interacts with |
SH3KBP1 | HPRD; |
interacts with |
SOCS1 | BIOGRID; |
interacts with |
SOCS1 | CELL_MAP; |
interacts with |
SOCS1 | HPRD; |
interacts with |
SOCS5 | HPRD; |
interacts with |
SOCS6 | HPRD; |
interacts with |
SPRED1 | CELL_MAP; |
interacts with |
SPRED1 | HPRD; |
interacts with |
SPRED2 | CELL_MAP; |
interacts with |
SPRED2 | HPRD; |
interacts with |
SRC | CELL_MAP; |
interacts with |
SRC | HPRD; |
interacts with |
STAP1 | HPRD; |
interacts with |
STAT1 | BIOGRID; |
interacts with |
STAT1 | CELL_MAP; |
interacts with |
STAT1 | HPRD; |
interacts with |
STAT5A | CELL_MAP; |
interacts with |
STAT5A | HPRD; |
interacts with |
STAT5B | CELL_MAP; |
interacts with |
STAT5B | HPRD; |
interacts with |
TEC | BIOGRID; |
interacts with |
TEC | HPRD; |
interacts with |
YES1 | BIOGRID; |
interacts with |
YES1 | CELL_MAP; |
interacts with |
YES1 | HPRD; |
Metabolic Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
metabolic catalysis |
CREBBP | NCI_NATURE; |
metabolic catalysis |
ETS2 | NCI_NATURE; |
metabolic catalysis |
MYB | NCI_NATURE; |
metabolic catalysis |
STAT1 | NCI_NATURE; |
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
EPO | NCI_NATURE; |
reacts with |
EPOR | NCI_NATURE; |
reacts with |
GAB2 | REACTOME; |
reacts with |
JAK2 | REACTOME; |
reacts with |
KIT | NCI_NATURE; |
reacts with |
KIT | REACTOME; |
reacts with |
KITLG | NCI_NATURE; |
reacts with |
PIK3CA | REACTOME; |
reacts with |
PRKCA | REACTOME; |
reacts with |
PTPN11 | REACTOME; |
reacts with |
PTPN6 | REACTOME; |
reacts with |
PTPRU | REACTOME; |
reacts with |
SH2B2 | REACTOME; |
reacts with |
SH2B3 | REACTOME; |
reacts with |
SOCS1 | REACTOME; |
reacts with |
SOCS6 | REACTOME; |
reacts with |
SOS1 | REACTOME; |
state change |
Fyn | CELL_MAP; |
state change |
GAB2 | REACTOME; |
state change |
JAK2 | REACTOME; |
state change |
KIT | CELL_MAP; |
state change |
KIT | REACTOME; |
state change |
LYN | CELL_MAP; |
state change |
PRKCA | CELL_MAP; |
state change |
PRKCA | REACTOME; |
state change |
PRKCB | CELL_MAP; |
state change |
PTPN11 | NCI_NATURE; |
state change |
PTPN11 | REACTOME; |
state change |
PTPN6 | NCI_NATURE; |
state change |
SH2B2 | REACTOME; |
state change |
SRC | CELL_MAP; |