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Basic Information
Gene ID	3665
Name	IRF7
Synonymous	interferon regulatory factor 7;IRF7;interferon regulatory factor 7
Definition	IRF-7\|interferon regulatory factor-7H
Position	11p15.5
Gene Type	protein-coding
Gene Interactions:	Physical Interaction Metabolic Interaction Signaling Interaction

Interaction Type	Interactor	Data Source
Physical Interaction [Top]
in same component	IRAK1	REACTOME;
in same component	IRAK4	REACTOME;
in same component	IRF3	REACTOME;
in same component	MAVS	REACTOME;
in same component	MYD88	REACTOME;
in same component	SMAD4	NCI_NATURE;
in same component	TANK	REACTOME;
in same component	TRAF6	REACTOME;
interacts with	ALK	BIOGRID;
interacts with	CREBBP	HPRD;
interacts with	Dlg4	MINT;
interacts with	EP300	HPRD;
interacts with	FADD	BIOGRID;
interacts with	IRAK1	HPRD;
interacts with	IRF3	BIOGRID;
interacts with	IRF3	HPRD;
interacts with	KAT2A	HPRD;
interacts with	KAT2B	HPRD;
interacts with	MAFB	INTACT;
interacts with	MAVS	HPRD;
interacts with	MYD88	BIOGRID;
interacts with	MYD88	HPRD;
interacts with	PIAS4	HPRD;
interacts with	PIAS4	MINT;
interacts with	TANK	BIOGRID;
interacts with	TBK1	MINT;
interacts with	TICAM1	HPRD;
interacts with	TICAM2	HPRD;
interacts with	TRAF6	BIOGRID;
interacts with	TRAF6	HPRD;

Interaction Type	Interactor	Data Source
Metabolic Interaction [Top]
sequential catalysis	IRAK1	REACTOME;
sequential catalysis	IRAK4	REACTOME;
sequential catalysis	IRF7	REACTOME;
sequential catalysis	MYD88	REACTOME;
sequential catalysis	TRAF6	REACTOME;

Interaction Type	Interactor	Data Source
Signaling Interaction [Top]
reacts with	IRAK1	REACTOME;
reacts with	IRAK4	REACTOME;
reacts with	IRF3	REACTOME;
reacts with	IRF7	NCI_NATURE;
reacts with	IRF7	REACTOME;
reacts with	MAVS	REACTOME;
reacts with	MYD88	REACTOME;
reacts with	SMAD4	NCI_NATURE;
reacts with	TANK	REACTOME;
reacts with	TRAF6	REACTOME;
reacts with	UBE2N	REACTOME;
reacts with	UBE2V1	REACTOME;
state change	IRAK1	REACTOME;
state change	IRAK4	REACTOME;
state change	IRF7	REACTOME;
state change	MAVS	REACTOME;
state change	MYD88	REACTOME;
state change	TANK	REACTOME;
state change	TRAF6	REACTOME;

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