| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3480 |
Name | IGF1R |
Synonymous | insulin-like growth factor 1 receptor;IGF1R;insulin-like growth factor 1 receptor |
Definition | IGF-I receptor|insulin-like growth factor I receptor|soluble IGF1R variant 1|soluble IGF1R variant 2 |
Position | 15q26.3 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
ARHGEF12 | IMID; |
in same component |
GRB10 | IMID; |
in same component |
GRB10 | NCI_NATURE; |
in same component |
IGF1 | IMID; |
in same component |
IGF1 | NCI_NATURE; |
in same component |
IGF2 | NCI_NATURE; |
in same component |
IRS1 | IMID; |
in same component |
IRS1 | NCI_NATURE; |
in same component |
NCK2 | NCI_NATURE; |
in same component |
PTPN11 | NCI_NATURE; |
in same component |
PTPN1 | NCI_NATURE; |
in same component |
SHC1 | IMID; |
in same component |
SHC1 | NCI_NATURE; |
in same component |
SOS1 | NCI_NATURE; |
interacts with |
ARHGEF12 | BIOGRID; |
interacts with |
ARHGEF12 | HPRD; |
interacts with |
Arhgef12 | MINT; |
interacts with |
ARHGEF12 | MINT; |
interacts with |
Arrb1 | BIOGRID; |
interacts with |
CAMP | BIOGRID; |
interacts with |
CAV1 | HPRD; |
interacts with |
CBL | BIOGRID; |
interacts with |
CBL | HPRD; |
interacts with |
CDH3 | INTACT; |
interacts with |
CRK | HPRD; |
interacts with |
Crk | MINT; |
interacts with |
CRKL | HPRD; |
interacts with |
CSK | BIOGRID; |
interacts with |
CSK | HPRD; |
interacts with |
CSK | MINT; |
interacts with |
DOK4 | HPRD; |
interacts with |
DOK5 | HPRD; |
interacts with |
EEA1 | BIOGRID; |
interacts with |
EEA1 | HPRD; |
interacts with |
EGFR | BIOGRID; |
interacts with |
EHD1 | BIOGRID; |
interacts with |
EHD1 | HPRD; |
interacts with |
ERBB2 | BIOGRID; |
interacts with |
ESR1 | BIOGRID; |
interacts with |
ESR1 | HPRD; |
interacts with |
GIGYF1 | HPRD; |
interacts with |
GIPC1 | HPRD; |
interacts with |
GNAI1 | BIOGRID; |
interacts with |
GNAI1 | HPRD; |
interacts with |
GNAI2 | HPRD; |
interacts with |
GRB10 | BIOGRID; |
interacts with |
GRB10 | HPRD; |
interacts with |
GRB10 | MINT; |
interacts with |
IGF1 | BIOGRID; |
interacts with |
IGF2 | HPRD; |
interacts with |
IGFBP3 | BIOGRID; |
interacts with |
IGFBP3 | HPRD; |
interacts with |
INS | HPRD; |
interacts with |
INSR | HPRD; |
interacts with |
IRS1 | BIOGRID; |
interacts with |
IRS1 | HPRD; |
interacts with |
IRS2 | HPRD; |
interacts with |
IRS4 | HPRD; |
interacts with |
ITGB1 | HPRD; |
interacts with |
JAK1 | BIOGRID; |
interacts with |
JAK1 | HPRD; |
interacts with |
JAK2 | HPRD; |
interacts with |
KL | HPRD; |
interacts with |
MAP3K5 | HPRD; |
interacts with |
MDM2 | BIOGRID; |
interacts with |
MDM2 | HPRD; |
interacts with |
NEDD4 | BIOGRID; |
interacts with |
NEDD4 | HPRD; |
interacts with |
PIK3R1 | HPRD; |
interacts with |
PIK3R1 | MINT; |
interacts with |
PIK3R2 | HPRD; |
interacts with |
PIK3R3 | BIOGRID; |
interacts with |
PIK3R3 | HPRD; |
interacts with |
Pik3r3 | MINT; |
interacts with |
PRKCD | HPRD; |
interacts with |
PRKD1 | HPRD; |
interacts with |
PTK2 | BIOGRID; |
interacts with |
PTPN11 | BIOGRID; |
interacts with |
PTPN11 | HPRD; |
interacts with |
PTPN11 | MINT; |
interacts with |
PTPN1 | BIOGRID; |
interacts with |
PTPN1 | HPRD; |
interacts with |
PTPN1 | MINT; |
interacts with |
PXN | BIOGRID; |
interacts with |
RASA1 | BIOGRID; |
interacts with |
RASA1 | HPRD; |
interacts with |
RASA1 | MINT; |
interacts with |
SHC1 | BIOGRID; |
interacts with |
SHC1 | HPRD; |
interacts with |
SNAP29 | BIOGRID; |
interacts with |
SNAP29 | HPRD; |
interacts with |
SOCS1 | BIOGRID; |
interacts with |
SOCS1 | HPRD; |
interacts with |
SOCS2 | BIOGRID; |
interacts with |
SOCS2 | HPRD; |
interacts with |
SOCS3 | BIOGRID; |
interacts with |
SOCS3 | HPRD; |
interacts with |
SRC | HPRD; |
interacts with |
STAT3 | HPRD; |
interacts with |
VAV3 | BIOGRID; |
interacts with |
VAV3 | HPRD; |
interacts with |
YWHAB | BIOGRID; |
interacts with |
YWHAB | HPRD; |
interacts with |
YWHAB | MINT; |
interacts with |
YWHAE | BIOGRID; |
interacts with |
YWHAE | HPRD; |
interacts with |
YWHAE | MINT; |
interacts with |
YWHAG | BIOGRID; |
interacts with |
YWHAG | HPRD; |
interacts with |
YWHAG | MINT; |
interacts with |
YWHAZ | HPRD; |
interacts with |
YWHAZ | MINT; |
Metabolic Interaction [Top] | ||
There is no record for IGF1R | ||
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
ARHGEF12 | IMID; |
reacts with |
CDH1 | NCI_NATURE; |
reacts with |
CTNNA1 | NCI_NATURE; |
reacts with |
CTNNB1 | NCI_NATURE; |
reacts with |
CTNND1 | NCI_NATURE; |
reacts with |
GRB10 | IMID; |
reacts with |
GRB10 | NCI_NATURE; |
reacts with |
IGF1 | IMID; |
reacts with |
IGF1 | NCI_NATURE; |
reacts with |
IGF1R | IMID; |
reacts with |
IGF1R | NCI_NATURE; |
reacts with |
IRS1 | IMID; |
reacts with |
IRS1 | NCI_NATURE; |
reacts with |
NCK2 | NCI_NATURE; |
reacts with |
PTPN11 | NCI_NATURE; |
reacts with |
PTPN1 | NCI_NATURE; |
reacts with |
SHC1 | IMID; |
reacts with |
SHC1 | NCI_NATURE; |
reacts with |
SOS1 | NCI_NATURE; |
state change |
CDH1 | NCI_NATURE; |
state change |
CTNNA1 | NCI_NATURE; |
state change |
CTNNB1 | NCI_NATURE; |
state change |
CTNND1 | NCI_NATURE; |
state change |
ESR1 | NCI_NATURE; |
state change |
FN1 | NCI_NATURE; |
state change |
ITGAV | NCI_NATURE; |
state change |
ITGB3 | NCI_NATURE; |
state change |
PELP1 | NCI_NATURE; |
state change |
SRC | NCI_NATURE; |