| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 332 |
Name | BIRC5 |
Synonymous | baculoviral IAP repeat containing 5;BIRC5;baculoviral IAP repeat containing 5 |
Definition | apoptosis inhibitor 4|apoptosis inhibitor survivin|baculoviral IAP repeat-containing protein 5|survivin variant 3 alpha |
Position | 17q25 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
AHCTF1 | REACTOME; |
in same component |
APITD1 | REACTOME; |
in same component |
AURKA | NCI_NATURE; |
in same component |
AURKB | NCI_NATURE; |
in same component |
AURKB | REACTOME; |
in same component |
B9D2 | REACTOME; |
in same component |
BUB1B | REACTOME; |
in same component |
BUB1 | REACTOME; |
in same component |
BUB3 | REACTOME; |
in same component |
CASC5 | REACTOME; |
in same component |
CASP3 | IMID; |
in same component |
CASP7 | IMID; |
in same component |
CCDC99 | REACTOME; |
in same component |
CDC20 | REACTOME; |
in same component |
CDCA8 | NCI_NATURE; |
in same component |
CDCA8 | REACTOME; |
in same component |
CENPA | REACTOME; |
in same component |
CENPC1 | REACTOME; |
in same component |
CENPE | REACTOME; |
in same component |
CENPF | REACTOME; |
in same component |
CENPH | REACTOME; |
in same component |
CENPI | REACTOME; |
in same component |
CENPK | REACTOME; |
in same component |
CENPL | REACTOME; |
in same component |
CENPM | REACTOME; |
in same component |
CENPN | REACTOME; |
in same component |
CENPO | REACTOME; |
in same component |
CENPP | REACTOME; |
in same component |
CENPQ | REACTOME; |
in same component |
CENPT | REACTOME; |
in same component |
CKAP5 | REACTOME; |
in same component |
CLASP1 | REACTOME; |
in same component |
CLASP2 | REACTOME; |
in same component |
CLIP1 | REACTOME; |
in same component |
CUL3 | NCI_NATURE; |
in same component |
DIABLO | IMID; |
in same component |
DSN1 | REACTOME; |
in same component |
ERCC6L | REACTOME; |
in same component |
EVI5 | NCI_NATURE; |
in same component |
INCENP | NCI_NATURE; |
in same component |
INCENP | REACTOME; |
in same component |
KIF18A | REACTOME; |
in same component |
KIF2A | REACTOME; |
in same component |
KIF2B | REACTOME; |
in same component |
KIF2C | REACTOME; |
in same component |
KLHL13 | NCI_NATURE; |
in same component |
KLHL9 | NCI_NATURE; |
in same component |
KNTC1 | REACTOME; |
in same component |
MAD1L1 | REACTOME; |
in same component |
MAD2L1 | REACTOME; |
in same component |
MAPRE1 | REACTOME; |
in same component |
MIS12 | REACTOME; |
in same component |
MLF1IP | REACTOME; |
in same component |
NDC80 | REACTOME; |
in same component |
NDE1 | REACTOME; |
in same component |
NDEL1 | REACTOME; |
in same component |
NSL1 | REACTOME; |
in same component |
NUDC | REACTOME; |
in same component |
NUF2 | REACTOME; |
in same component |
NUP107 | REACTOME; |
in same component |
NUP133 | REACTOME; |
in same component |
NUP160 | REACTOME; |
in same component |
NUP37 | REACTOME; |
in same component |
NUP43 | REACTOME; |
in same component |
NUP85 | REACTOME; |
in same component |
PAFAH1B1 | REACTOME; |
in same component |
PLK1 | REACTOME; |
in same component |
PMF1 | REACTOME; |
in same component |
PPP1CC | REACTOME; |
in same component |
RANBP2 | REACTOME; |
in same component |
RANGAP1 | REACTOME; |
in same component |
RASA1 | NCI_NATURE; |
in same component |
RCC2 | REACTOME; |
in same component |
RPS27 | REACTOME; |
in same component |
SEC13 | REACTOME; |
in same component |
SGOL1 | NCI_NATURE; |
in same component |
SGOL1 | REACTOME; |
in same component |
SGOL2 | REACTOME; |
in same component |
SKA1 | REACTOME; |
in same component |
SKA2 | REACTOME; |
in same component |
SPC24 | REACTOME; |
in same component |
SPC25 | REACTOME; |
in same component |
TAOK1 | REACTOME; |
in same component |
XPO1 | REACTOME; |
in same component |
ZW10 | REACTOME; |
in same component |
ZWILCH | REACTOME; |
in same component |
ZWINT | REACTOME; |
interacts with |
AURKB | BIOGRID; |
interacts with |
AURKB | HPRD; |
interacts with |
AURKB | MINT; |
interacts with |
BECN1 | MINT; |
interacts with |
BIRC2 | BIOGRID; |
interacts with |
BIRC3 | BIOGRID; |
interacts with |
BIRC6 | HPRD; |
interacts with |
CASP3 | BIOGRID; |
interacts with |
CASP3 | HPRD; |
interacts with |
CASP7 | BIOGRID; |
interacts with |
CASP7 | HPRD; |
interacts with |
CASP9 | BIOGRID; |
interacts with |
CASP9 | HPRD; |
interacts with |
CDCA8 | BIOGRID; |
interacts with |
CDCA8 | HPRD; |
interacts with |
CDCA8 | MINT; |
interacts with |
CDK2 | BIOGRID; |
interacts with |
CDK4 | BIOGRID; |
interacts with |
CDK4 | HPRD; |
interacts with |
CENPA | HPRD; |
interacts with |
DIABLO | BIOGRID; |
interacts with |
DIABLO | HPRD; |
interacts with |
EVI5 | BIOGRID; |
interacts with |
H2AFX | BIOGRID; |
interacts with |
HSP90AA1 | HPRD; |
interacts with |
INCENP | BIOGRID; |
interacts with |
INCENP | HPRD; |
interacts with |
INCENP | INTACT; |
interacts with |
INCENP | MINT; |
interacts with |
JTB | INTACT; |
interacts with |
KCNJ6 | BIOGRID; |
interacts with |
MDC1 | BIOGRID; |
interacts with |
PRKDC | BIOGRID; |
interacts with |
RASA1 | HPRD; |
interacts with |
UFD1L | BIOGRID; |
interacts with |
USF2 | BIOGRID; |
interacts with |
USP9X | BIOGRID; |
interacts with |
XIAP | BIOGRID; |
interacts with |
XIAP | HPRD; |
interacts with |
XPO1 | HPRD; |
interacts with |
XPO1 | MINT; |
interacts with |
XRCC6 | BIOGRID; |
Metabolic Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
metabolic catalysis |
FOXM1 | NCI_NATURE; |
metabolic catalysis |
MAX | NCI_NATURE; |
metabolic catalysis |
MYC | NCI_NATURE; |
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
AHCTF1 | REACTOME; |
reacts with |
APITD1 | REACTOME; |
reacts with |
AURKA | NCI_NATURE; |
reacts with |
AURKB | NCI_NATURE; |
reacts with |
AURKB | REACTOME; |
reacts with |
B9D2 | REACTOME; |
reacts with |
BIRC5 | IMID; |
reacts with |
BIRC5 | NCI_NATURE; |
reacts with |
BIRC5 | REACTOME; |
reacts with |
BUB1B | REACTOME; |
reacts with |
BUB1 | REACTOME; |
reacts with |
BUB3 | REACTOME; |
reacts with |
CASC5 | REACTOME; |
reacts with |
CASP3 | IMID; |
reacts with |
CASP7 | IMID; |
reacts with |
CCDC99 | REACTOME; |
reacts with |
CDC20 | REACTOME; |
reacts with |
CDCA8 | NCI_NATURE; |
reacts with |
CDCA8 | REACTOME; |
reacts with |
CENPA | REACTOME; |
reacts with |
CENPC1 | REACTOME; |
reacts with |
CENPE | REACTOME; |
reacts with |
CENPF | REACTOME; |
reacts with |
CENPH | REACTOME; |
reacts with |
CENPI | REACTOME; |
reacts with |
CENPK | REACTOME; |
reacts with |
CENPL | REACTOME; |
reacts with |
CENPM | REACTOME; |
reacts with |
CENPN | REACTOME; |
reacts with |
CENPO | REACTOME; |
reacts with |
CENPP | REACTOME; |
reacts with |
CENPQ | REACTOME; |
reacts with |
CENPT | REACTOME; |
reacts with |
CKAP5 | REACTOME; |
reacts with |
CLASP1 | REACTOME; |
reacts with |
CLASP2 | REACTOME; |
reacts with |
CLIP1 | REACTOME; |
reacts with |
CUL3 | NCI_NATURE; |
reacts with |
DIABLO | IMID; |
reacts with |
DSN1 | REACTOME; |
reacts with |
ERCC6L | REACTOME; |
reacts with |
EVI5 | NCI_NATURE; |
reacts with |
INCENP | NCI_NATURE; |
reacts with |
INCENP | REACTOME; |
reacts with |
KIF18A | REACTOME; |
reacts with |
KIF2A | REACTOME; |
reacts with |
KIF2B | REACTOME; |
reacts with |
KIF2C | REACTOME; |
reacts with |
KLHL13 | NCI_NATURE; |
reacts with |
KLHL9 | NCI_NATURE; |
reacts with |
KNTC1 | REACTOME; |
reacts with |
MAD1L1 | REACTOME; |
reacts with |
MAD2L1 | REACTOME; |
reacts with |
MAPRE1 | REACTOME; |
reacts with |
MIS12 | REACTOME; |
reacts with |
MLF1IP | REACTOME; |
reacts with |
NDC80 | REACTOME; |
reacts with |
NDE1 | REACTOME; |
reacts with |
NDEL1 | REACTOME; |
reacts with |
NSL1 | REACTOME; |
reacts with |
NUDC | REACTOME; |
reacts with |
NUF2 | REACTOME; |
reacts with |
NUP107 | REACTOME; |
reacts with |
NUP133 | REACTOME; |
reacts with |
NUP160 | REACTOME; |
reacts with |
NUP37 | REACTOME; |
reacts with |
NUP43 | REACTOME; |
reacts with |
NUP85 | REACTOME; |
reacts with |
PAFAH1B1 | REACTOME; |
reacts with |
PLK1 | REACTOME; |
reacts with |
PMF1 | REACTOME; |
reacts with |
PPP1CC | REACTOME; |
reacts with |
PSMA3 | NCI_NATURE; |
reacts with |
RANBP2 | REACTOME; |
reacts with |
RANGAP1 | REACTOME; |
reacts with |
RASA1 | NCI_NATURE; |
reacts with |
RCC2 | REACTOME; |
reacts with |
RPS27 | REACTOME; |
reacts with |
SEC13 | REACTOME; |
reacts with |
SGOL1 | NCI_NATURE; |
reacts with |
SGOL1 | REACTOME; |
reacts with |
SGOL2 | REACTOME; |
reacts with |
SKA1 | REACTOME; |
reacts with |
SKA2 | REACTOME; |
reacts with |
SPC24 | REACTOME; |
reacts with |
SPC25 | REACTOME; |
reacts with |
TAOK1 | REACTOME; |
reacts with |
XPO1 | REACTOME; |
reacts with |
ZW10 | REACTOME; |
reacts with |
ZWILCH | REACTOME; |
reacts with |
ZWINT | REACTOME; |
state change |
BUB1 | NCI_NATURE; |
state change |
CENPA | NCI_NATURE; |
state change |
KIF20A | NCI_NATURE; |
state change |
PEBP1 | NCI_NATURE; |