| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 2475 |
Name | MTOR |
Synonymous | mechanistic target of rapamycin (serine/threonine kinase);MTOR;mechanistic target of rapamycin (serine/threonine kinase) |
Definition | FK506 binding protein 12-rapamycin associated protein 2|FK506-binding protein 12-rapamycin complex-associated protein 1|FKBP-rapamycin associated protein|FKBP12-rapamycin complex-associated protein 1|mammalian target of rapamycin|rapamycin and FKBP12 targ |
Position | 1p36.2 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
AKT1 | NCI_NATURE; |
in same component |
AKT1S1 | NCI_NATURE; |
in same component |
ATG13 | NCI_NATURE; |
in same component |
DEPTOR | NCI_NATURE; |
in same component |
DKC1 | NCI_NATURE; |
in same component |
HSP90AA1 | NCI_NATURE; |
in same component |
MAPKAP1 | NCI_NATURE; |
in same component |
MLST8 | NCI_NATURE; |
in same component |
MLST8 | REACTOME; |
in same component |
PPARGC1A | NCI_NATURE; |
in same component |
PTGES3 | NCI_NATURE; |
in same component |
RB1CC1 | NCI_NATURE; |
in same component |
RHEB | REACTOME; |
in same component |
RICTOR | NCI_NATURE; |
in same component |
RICTOR | REACTOME; |
in same component |
RPS6KB1 | NCI_NATURE; |
in same component |
RPTOR | NCI_NATURE; |
in same component |
TERT | NCI_NATURE; |
in same component |
YY1 | NCI_NATURE; |
interacts with |
ABL1 | BIOGRID; |
interacts with |
AKT1 | BIOGRID; |
interacts with |
AKT1 | HPRD; |
interacts with |
AKT1 | MINT; |
interacts with |
AKT1S1 | HPRD; |
interacts with |
ATM | INTACT; |
interacts with |
ATR | INTACT; |
interacts with |
CFP | BIOGRID; |
interacts with |
CLIP1 | BIOGRID; |
interacts with |
EIF3B | BIOGRID; |
interacts with |
EIF3B | HPRD; |
interacts with |
EIF3C | BIOGRID; |
interacts with |
EIF3F | BIOGRID; |
interacts with |
EIF3F | HPRD; |
interacts with |
EIF4EBP1 | BIOGRID; |
interacts with |
EIF4EBP1 | HPRD; |
interacts with |
Eif4ebp1 | MINT; |
interacts with |
FBXW7 | BIOGRID; |
interacts with |
FKBP1A | BIOGRID; |
interacts with |
FKBP1A | HPRD; |
interacts with |
GNB1L | HPRD; |
interacts with |
GPHN | BIOGRID; |
interacts with |
GPHN | HPRD; |
interacts with |
IRS1 | BIOGRID; |
interacts with |
IRS1 | HPRD; |
interacts with |
LRPAP1 | BIOGRID; |
interacts with |
MAPKAP1 | BIOGRID; |
interacts with |
MAPKAP1 | INTACT; |
interacts with |
MAPKAP1 | MINT; |
interacts with |
MLST8 | BIOGRID; |
interacts with |
MLST8 | HPRD; |
interacts with |
MLST8 | INTACT; |
interacts with |
PA2G4 | BIOGRID; |
interacts with |
PDPK1 | HPRD; |
interacts with |
PDPK1 | MINT; |
interacts with |
PLD2 | BIOGRID; |
interacts with |
PLD2 | HPRD; |
interacts with |
POLR2E | INTACT; |
interacts with |
PPP2R2A | BIOGRID; |
interacts with |
PRKAA1 | BIOGRID; |
interacts with |
PRKAA1 | HPRD; |
interacts with |
PRKCD | BIOGRID; |
interacts with |
PRKDC | INTACT; |
interacts with |
RAP1A | BIOGRID; |
interacts with |
RHEBL1 | HPRD; |
interacts with |
RHEBL1 | MINT; |
interacts with |
Rheb | BIOGRID; |
interacts with |
RHEB | BIOGRID; |
interacts with |
RHEB | HPRD; |
interacts with |
RHEB | MINT; |
interacts with |
RICTOR | BIOGRID; |
interacts with |
RICTOR | HPRD; |
interacts with |
RICTOR | INTACT; |
interacts with |
RICTOR | MINT; |
interacts with |
RPL17 | INTACT; |
interacts with |
RPL7 | INTACT; |
interacts with |
RPS6KA1 | HPRD; |
interacts with |
Rps6kb1 | BIOGRID; |
interacts with |
RPS6KB1 | BIOGRID; |
interacts with |
RPS6KB1 | HPRD; |
interacts with |
RPS6KB2 | HPRD; |
interacts with |
RPTOR | BIOGRID; |
interacts with |
RPTOR | HPRD; |
interacts with |
RPTOR | MINT; |
interacts with |
RUVBL1 | INTACT; |
interacts with |
RUVBL2 | INTACT; |
interacts with |
SMG1 | INTACT; |
interacts with |
STAT1 | BIOGRID; |
interacts with |
Stat3 | BIOGRID; |
interacts with |
STAT3 | BIOGRID; |
interacts with |
STAT3 | HPRD; |
interacts with |
STK38 | MINT; |
interacts with |
TELO2 | BIOGRID; |
interacts with |
TERT | BIOGRID; |
interacts with |
TERT | HPRD; |
interacts with |
TP53 | MINT; |
interacts with |
TRAF2 | MINT; |
interacts with |
TRRAP | INTACT; |
interacts with |
tti1 | BIOGRID; |
interacts with |
TTI1 | BIOGRID; |
interacts with |
TTI1 | INTACT; |
interacts with |
UBQLN1 | BIOGRID; |
interacts with |
UBQLN1 | HPRD; |
interacts with |
YWHAQ | HPRD; |
interacts with |
YWHAZ | MINT; |
Metabolic Interaction [Top] | ||
There is no record for MTOR | ||
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
AKT1 | NCI_NATURE; |
reacts with |
AKT1S1 | NCI_NATURE; |
reacts with |
ATG13 | NCI_NATURE; |
reacts with |
DEPTOR | NCI_NATURE; |
reacts with |
DKC1 | NCI_NATURE; |
reacts with |
HSP90AA1 | NCI_NATURE; |
reacts with |
MAPKAP1 | NCI_NATURE; |
reacts with |
MLST8 | NCI_NATURE; |
reacts with |
MLST8 | REACTOME; |
reacts with |
MTOR | NCI_NATURE; |
reacts with |
MTOR | REACTOME; |
reacts with |
PPARGC1A | NCI_NATURE; |
reacts with |
PTGES3 | NCI_NATURE; |
reacts with |
RB1CC1 | NCI_NATURE; |
reacts with |
RHEB | REACTOME; |
reacts with |
RICTOR | NCI_NATURE; |
reacts with |
RPS6KB1 | NCI_NATURE; |
reacts with |
RPTOR | NCI_NATURE; |
reacts with |
TERT | NCI_NATURE; |
reacts with |
YY1 | NCI_NATURE; |
state change |
AKT1 | NCI_NATURE; |
state change |
CDC42 | NCI_NATURE; |
state change |
EGF | NCI_NATURE; |
state change |
EGFR | NCI_NATURE; |
state change |
IL2 | NCI_NATURE; |
state change |
PIK3CA | NCI_NATURE; |
state change |
PIK3R1 | NCI_NATURE; |
state change |
RHEB | NCI_NATURE; |
state change |
SOS1 | NCI_NATURE; |
state change |
TSC1 | NCI_NATURE; |
state change |
TSC2 | NCI_NATURE; |