| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 11073 |
Name | TOPBP1 |
Synonymous | topoisomerase (DNA) II binding protein 1;TOPBP1;topoisomerase (DNA) II binding protein 1 |
Definition | DNA topoisomerase 2-binding protein 1|DNA topoisomerase II-beta-binding protein 1|DNA topoisomerase II-binding protein 1 |
Position | 3q22.1 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
ATRIP | NCI_NATURE; |
in same component |
ATR | NCI_NATURE; |
in same component |
BARD1 | NCI_NATURE; |
in same component |
BRCA1 | NCI_NATURE; |
in same component |
CDC6 | NCI_NATURE; |
in same component |
CEP164 | NCI_NATURE; |
in same component |
CHEK1 | NCI_NATURE; |
in same component |
CLSPN | NCI_NATURE; |
in same component |
E2F1 | NCI_NATURE; |
in same component |
HUS1 | NCI_NATURE; |
in same component |
RAD17 | NCI_NATURE; |
in same component |
RAD1 | NCI_NATURE; |
in same component |
RAD9A | NCI_NATURE; |
in same component |
RFC2 | NCI_NATURE; |
in same component |
RFC3 | NCI_NATURE; |
in same component |
RFC4 | NCI_NATURE; |
in same component |
RFC5 | NCI_NATURE; |
in same component |
RPA1 | NCI_NATURE; |
in same component |
RPA2 | NCI_NATURE; |
in same component |
SMARCAL1 | NCI_NATURE; |
in same component |
TIMELESS | NCI_NATURE; |
in same component |
TIPIN | NCI_NATURE; |
interacts with |
ABL1 | BIOGRID; |
interacts with |
AKT1 | MINT; |
interacts with |
ATR | BIOGRID; |
interacts with |
BRIP1 | BIOGRID; |
interacts with |
CALCR | BIOGRID; |
interacts with |
CLK2 | BIOGRID; |
interacts with |
E2F1 | BIOGRID; |
interacts with |
E2F1 | MINT; |
interacts with |
MSH6 | BIOGRID; |
interacts with |
MYC | MINT; |
interacts with |
NBN | BIOGRID; |
interacts with |
PIAS2 | MINT; |
interacts with |
PMS2 | BIOGRID; |
interacts with |
POLE | BIOGRID; |
interacts with |
RAD9A | BIOGRID; |
interacts with |
RAD9A | MINT; |
interacts with |
RPA1 | BIOGRID; |
interacts with |
RPAP2 | BIOGRID; |
interacts with |
SMARCA4 | BIOGRID; |
interacts with |
TOP1 | MINT; |
interacts with |
TOP2B | BIOGRID; |
interacts with |
UBR5 | BIOGRID; |
interacts with |
ZBTB17 | BIOGRID; |
interacts with |
ZBTB17 | MINT; |
Metabolic Interaction [Top] | ||
There is no record for TOPBP1 | ||
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
ATRIP | NCI_NATURE; |
reacts with |
ATR | NCI_NATURE; |
reacts with |
BARD1 | NCI_NATURE; |
reacts with |
BRCA1 | NCI_NATURE; |
reacts with |
CDC6 | NCI_NATURE; |
reacts with |
CEP164 | NCI_NATURE; |
reacts with |
CHEK1 | NCI_NATURE; |
reacts with |
CLSPN | NCI_NATURE; |
reacts with |
E2F1 | NCI_NATURE; |
reacts with |
HUS1 | NCI_NATURE; |
reacts with |
RAD17 | NCI_NATURE; |
reacts with |
RAD1 | NCI_NATURE; |
reacts with |
RAD9A | NCI_NATURE; |
reacts with |
RFC2 | NCI_NATURE; |
reacts with |
RFC3 | NCI_NATURE; |
reacts with |
RFC4 | NCI_NATURE; |
reacts with |
RFC5 | NCI_NATURE; |
reacts with |
RPA1 | NCI_NATURE; |
reacts with |
RPA2 | NCI_NATURE; |
reacts with |
SMARCAL1 | NCI_NATURE; |
reacts with |
TIMELESS | NCI_NATURE; |
reacts with |
TIPIN | NCI_NATURE; |
reacts with |
TOPBP1 | NCI_NATURE; |
state change |
YWHAZ | NCI_NATURE; |