| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 7298 |
Name | TYMS |
Synonym | HST422|TMS|TS;thymidylate synthetase;TYMS;thymidylate synthetase |
Definition | TSase|thymidylate synthase |
Position | 18p11.32 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | E2F transcription factor network;PID Curated;200027 |
Pathway | Formyltetrahydroformate biosynthesis;PANTHER;P02743 |
Pathway | De novo pyrimidine deoxyribonucleotide biosynthesis;PANTHER;P02739 |
Pathway | pyrimidine deoxyribonucleotides de novo biosynthesis;BioCyc;PWY0-166 |
Pathway | One carbon pool by folate;KEGG PATHWAY;hsa00670 |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
Pathway | Pyrimidine metabolism;KEGG PATHWAY;hsa00240 |
Pathway | Cell Cycle, Mitotic;Reactome;REACT:152 |
Pathway | Tetrahydrofolate biosynthesis;PANTHER;P02742 |
Pathway | Metabolism of nucleotides;Reactome;REACT:1698 |
Disease | Central nervous system disease;FunDO |
Disease | Cytomegalovirus infection;FunDO |
Disease | Cancer;FunDO |
Disease | DEVELOPMENTAL;GAD |
Disease | neural tube defects;GAD |
Disease | lung cancer;GAD |
Disease | PHARMACOGENOMIC;GAD |
Disease | Rheumatoid arthritis;FunDO |
Disease | head and neck cancer;GAD |
Disease | METABOLIC;GAD |
Disease | colorectal cancer;GAD |
Disease | folate;GAD |
Disease | esophageal cancer;GAD |
Disease | Thrombophlebitis;FunDO |
Disease | CANCER;GAD |
Disease | Hypertension;FunDO |
Disease | leukemia;GAD |
Disease | Abortion;FunDO |
Disease | methotrexate toxicity;GAD |
Disease | stomach cancer;GAD |
Disease | homocystinuria;GAD |
Disease | Folic acid deficiency;FunDO |
External Links | |
Links to Entrez Gene | 7298 |
Links to all GeneRIF Items | 7298 |
Links to iHOP | 7298 |
Sequence Information | |
Nucleotide Sequence | >7298 : length: 1603 CGGGACGGCCGCGGGAAAAGGCGCGCGGAAGGGGTCCTGCCACCGCGCCACTTGGCCTGC CTCCGTCCCGCCGCGCCACTTGGCCTGCCTCCGTCCCGCCGCGCCACTTCGCCTGCCTCC GTCCCCCGCCCGCCGCGCCATGCCTGTGGCCGGCTCGGAGCTGCCGCGCCGGCCCTTGCC CCCCGCCGCACAGGAGCGGGACGCCGAGCCGCGTCCGCCGCACGGGGAGCTGCAGTACCT GGGGCAGATCCAACACATCCTCCGCTGCGGCGTCAGGAAGGACGACCGCACGGGCACCGG CACCCTGTCGGTATTCGGCATGCAGGCGCGCTACAGCCTGAGAGATGAATTCCCTCTGCT GACAACCAAACGTGTGTTCTGGAAGGGTGTTTTGGAGGAGTTGCTGTGGTTTATCAAGGG ATCCACAAATGCTAAAGAGCTGTCTTCCAAGGGAGTGAAAATCTGGGATGCCAATGGATC CCGAGACTTTTTGGACAGCCTGGGATTCTCCACCAGAGAAGAAGGGGACTTGGGCCCAGT TTATGGCTTCCAGTGGAGGCATTTTGGGGCAGAATACAGAGATATGGAATCAGATTATTC AGGACAGGGAGTTGACCAACTGCAAAGAGTGATTGACACCATCAAAACCAACCCTGACGA CAGAAGAATCATCATGTGCGCTTGGAATCCAAGAGATCTTCCTCTGATGGCGCTGCCTCC ATGCCATGCCCTCTGCCAGTTCTATGTGGTGAACAGTGAGCTGTCCTGCCAGCTGTACCA GAGATCGGGAGACATGGGCCTCGGTGTGCCTTTCAACATCGCCAGCTACGCCCTGCTCAC GTACATGATTGCGCACATCACGGGCCTGAAGCCAGGTGACTTTATACACACTTTGGGAGA TGCACATATTTACCTGAATCACATCGAGCCACTGAAAATTCAGCTTCAGCGAGAACCCAG ACCTTTCCCAAAGCTCAGGATTCTTCGAAAAGTTGAGAAAATTGATGACTTCAAAGCTGA AGACTTTCAGATTGAAGGGTACAATCCGCATCCAACTATTAAAATGGAAATGGCTGTTTA GGGTGCTTTCAAAGGAGCTCGAAGGATATTGTCAGTCTTTAGGGGTTGGGCTGGATGCCG AGGTAAAAGTTCTTTTTGCTCTAAAAGAAAAAGGAACTAGGTCAAAAATCTGTCCGTGAC CTATCAGTTATTAATTTTTAAGGATGTTGCCACTGGCAAATGTAACTGTGCCAGTTCTTT CCATAATAAAAGGCTTTGAGTTAACTCACTGAGGGTATCTGACAATGCTGAGGTTATGAA CAAAGTGAGGAGAATGAAATGTATGTGCTCTTAGCAAAAACATGTATGTGCATTTCAATC CCACGTACTTATAAAGAAGGTTGGTGAATTTCACAAGCTATTTTTGGAATATTTTTAGAA TATTTTAAGAATTTCACAAGCTATTCCCTCAAATCTGAGGGAGCTGAGTAACACCATCGA TCATGATGTAGAGTGTGGTTATGAACTTTAAAGTTATAGTTGTTTTATATGTTGCTATAA TAAAGAAGTGTTCTGCATTCGTCAAAAAAAAAAAAAAAAAAAA |
Protein Sequence | >7298 : length: 313 MPVAGSELPRRPLPPAAQERDAEPRPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFG MQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDS LGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMC AWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHI TGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEG YNPHPTIKMEMAV |