| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 6720 |
Name | SREBF1 |
Synonym | SREBP-1c|SREBP1|bHLHd1;sterol regulatory element binding transcription factor 1;SREBF1;sterol regulatory element binding transcription factor 1 |
Definition | SREBP-1|class D basic helix-loop-helix protein 1|sterol regulatory element-binding protein 1 |
Position | 17p11.2 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Insulin signaling pathway;KEGG PATHWAY;hsa04910 |
Pathway | RXR and RAR heterodimerization with other nuclear receptor;PID Curated;200112 |
Pathway | Caspase cascade in apoptosis;PID Curated;200148 |
Pathway | srebp control of lipid synthesis;PID BioCarta;100038 |
Pathway | caspase cascade in apoptosis;PID BioCarta;100218 |
Pathway | mTOR signaling pathway;PID Curated;200080 |
Disease | Atherosclerosis;GAD |
Disease | diabetes, type 2;GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | obesity;GAD |
Disease | METABOLIC;GAD |
External Links | |
Links to Entrez Gene | 6720 |
Links to all GeneRIF Items | 6720 |
Links to iHOP | 6720 |
Sequence Information | |
Nucleotide Sequence | >6720 : length: 5012 AGCAGAGCTGCGGCCGGGGGAACCCAGTTTCCGAGGAACTTTTCGCCGGCGCCGGGCCGC CTCTGAGGCCAGGGCAGGACACGAACGCGCGGAGCGGCGGCGGCGACTGAGAGCCGGGGC CGCGGCGGCGCTCCCTAGGAAGGGCCGTACGAGGCGGCGGGCCCGGCGGGCCTCCCGGAG GAGGCGGCTGCGCCATGGACGAGCCACCCTTCAGCGAGGCGGCTTTGGAGCAGGCGCTGG GCGAGCCGTGCGATCTGGACGCGGCGCTGCTGACCGACATCGAAGGTGAAGTCGGCGCGG GGAGGGGTAGGGCCAACGGCCTGGACGCCCCAAGGGCGGGCGCAGATCGCGGAGCCATGG ATTGCACTTTCGAAGACATGCTTCAGCTTATCAACAACCAAGACAGTGACTTCCCTGGCC TATTTGACCCACCCTATGCTGGGAGTGGGGCAGGGGGCACAGACCCTGCCAGCCCCGATA CCAGCTCCCCAGGCAGCTTGTCTCCACCTCCTGCCACATTGAGCTCCTCTCTTGAAGCCT TCCTGAGCGGGCCGCAGGCAGCGCCCTCACCCCTGTCCCCTCCCCAGCCTGCACCCACTC CATTGAAGATGTACCCGTCCATGCCCGCTTTCTCCCCTGGGCCTGGTATCAAGGAAGAGT CAGTGCCACTGAGCATCCTGCAGACCCCCACCCCACAGCCCCTGCCAGGGGCCCTCCTGC CACAGAGCTTCCCAGCCCCAGCCCCACCGCAGTTCAGCTCCACCCCTGTGTTAGGCTACC CCAGCCCTCCGGGAGGCTTCTCTACAGGAAGCCCTCCCGGGAACACCCAGCAGCCGCTGC CTGGCCTGCCACTGGCTTCCCCGCCAGGGGTCCCGCCCGTCTCCTTGCACACCCAGGTCC AGAGTGTGGTCCCCCAGCAGCTACTGACAGTCACAGCTGCCCCCACGGCAGCCCCTGTAA CGACCACTGTGACCTCGCAGATCCAGCAGGTCCCGGTCCTGCTGCAGCCCCACTTCATCA AGGCAGACTCGCTGCTTCTGACAGCCATGAAGACAGACGGAGCCACTGTGAAGGCGGCAG GTCTCAGTCCCCTGGTCTCTGGCACCACTGTGCAGACAGGGCCTTTGCCGACCCTGGTGA GTGGCGGAACCATCTTGGCAACAGTCCCACTGGTCGTAGATGCGGAGAAGCTGCCTATCA ACCGGCTCGCAGCTGGCAGCAAGGCCCCGGCCTCTGCCCAGAGCCGTGGAGAGAAGCGCA CAGCCCACAACGCCATTGAGAAGCGCTACCGCTCCTCCATCAATGACAAAATCATTGAGC TCAAGGATCTGGTGGTGGGCACTGAGGCAAAGCTGAATAAATCTGCTGTCTTGCGCAAGG CCATCGACTACATTCGCTTTCTGCAACACAGCAACCAGAAACTCAAGCAGGAGAACCTAA GTCTGCGCACTGCTGTCCACAAAAGCAAATCTCTGAAGGATCTGGTGTCGGCCTGTGGCA GTGGAGGGAACACAGACGTGCTCATGGAGGGCGTGAAGACTGAGGTGGAGGACACACTGA CCCCACCCCCCTCGGATGCTGGCTCACCTTTCCAGAGCAGCCCCTTGTCCCTTGGCAGCA GGGGCAGTGGCAGCGGTGGCAGTGGCAGTGACTCGGAGCCTGACAGCCCAGTCTTTGAGG ACAGCAAGGCAAAGCCAGAGCAGCGGCCGTCTCTGCACAGCCGGGGCATGCTGGACCGCT CCCGCCTGGCCCTGTGCACGCTCGTCTTCCTCTGCCTGTCCTGCAACCCCTTGGCCTCCT TGCTGGGGGCCCGGGGGCTTCCCAGCCCCTCAGATACCACCAGCGTCTACCATAGCCCTG GGCGCAACGTGCTGGGCACCGAGAGCAGAGATGGCCCTGGCTGGGCCCAGTGGCTGCTGC CCCCAGTGGTCTGGCTGCTCAATGGGCTGTTGGTGCTCGTCTCCTTGGTGCTTCTCTTTG TCTACGGTGAGCCAGTCACACGGCCCCACTCAGGCCCCGCCGTGTACTTCTGGAGGCATC GCAAGCAGGCTGACCTGGACCTGGCCCGGGGAGACTTTGCCCAGGCTGCCCAGCAGCTGT GGCTGGCCCTGCGGGCACTGGGCCGGCCCCTGCCCACCTCCCACCTGGACCTGGCTTGTA GCCTCCTCTGGAACCTCATCCGTCACCTGCTGCAGCGTCTCTGGGTGGGCCGCTGGCTGG CAGGCCGGGCAGGGGGCCTGCAGCAGGACTGTGCTCTGCGAGTGGATGCTAGCGCCAGCG CCCGAGACGCAGCCCTGGTCTACCATAAGCTGCACCAGCTGCACACCATGGGGAAGCACA CAGGCGGGCACCTCACTGCCACCAACCTGGCGCTGAGTGCCCTGAACCTGGCAGAGTGTG CAGGGGATGCCGTGTCTGTGGCGACGCTGGCCGAGATCTATGTGGCGGCTGCATTGAGAG TGAAGACCAGTCTCCCACGGGCCTTGCATTTTCTGACACGCTTCTTCCTGAGCAGTGCCC GCCAGGCCTGCCTGGCACAGAGTGGCTCAGTGCCTCCTGCCATGCAGTGGCTCTGCCACC CCGTGGGCCACCGTTTCTTCGTGGATGGGGACTGGTCCGTGCTCAGTACCCCATGGGAGA GCCTGTACAGCTTGGCCGGGAACCCAGTGGACCCCCTGGCCCAGGTGACTCAGCTATTCC GGGAACATCTCTTAGAGCGAGCACTGAACTGTGTGACCCAGCCCAACCCCAGCCCTGGGT CAGCTGATGGGGACAAGGAATTCTCGGATGCCCTCGGGTACCTGCAGCTGCTGAACAGCT GTTCTGATGCTGCGGGGGCTCCTGCCTACAGCTTCTCCATCAGTTCCAGCATGGCCACCA CCACCGGCGTAGACCCGGTGGCCAAGTGGTGGGCCTCTCTGACAGCTGTGGTGATCCACT GGCTGCGGCGGGATGAGGAGGCGGCTGAGCGGCTGTGCCCGCTGGTGGAGCACCTGCCCC GGGTGCTGCAGGAGTCTGAGAGACCCCTGCCCAGGGCAGCTCTGCACTCCTTCAAGGCTG CCCGGGCCCTGCTGGGCTGTGCCAAGGCAGAGTCTGGTCCAGCCAGCCTGACCATCTGTG AGAAGGCCAGTGGGTACCTGCAGGACAGCCTGGCTACCACACCAGCCAGCAGCTCCATTG ACAAGGCCGTGCAGCTGTTCCTGTGTGACCTGCTTCTTGTGGTGCGCACCAGCCTGTGGC GGCAGCAGCAGCCCCCGGCCCCGGCCCCAGCAGCCCAGGGCACCAGCAGCAGGCCCCAGG CTTCCGCCCTTGAGCTGCGTGGCTTCCAACGGGACCTGAGCAGCCTGAGGCGGCTGGCAC AGAGCTTCCGGCCCGCCATGCGGAGGGTGTTCCTACATGAGGCCACGGCCCGGCTGATGG CGGGGGCCAGCCCCACACGGACACACCAGCTCCTCGACCGCAGTCTGAGGCGGCGGGCAG GCCCCGGTGGCAAAGGAGGCGCGGTGGCGGAGCTGGAGCCGCGGCCCACGCGGCGGGAGC ACGCGGAGGCCTTGCTGCTGGCCTCCTGCTACCTGCCCCCCGGCTTCCTGTCGGCGCCCG GGCAGCGCGTGGGCATGCTGGCTGAGGCGGCGCGCACACTCGAGAAGCTTGGCGATCGCC GGCTGCTGCACGACTGTCAGCAGATGCTCATGCGCCTGGGCGGTGGGACCACTGTCACTT CCAGCTAGACCCCGTGTCCCCGGCCTCAGCACCCCTGTCTCTAGCCACTTTGGTCCCGTG CAGCTTCTGTCCTGCGTCGAAGCTTTGAAGGCCGAAGGCAGTGCAAGAGACTCTGGCCTC CACAGTTCGACCTGCGGCTGCTGTGTGCCTTCGCGGTGGAAGGCCCGAGGGGCGCGATCT TGACCCTAAGACCGGCGGCCATGATGGTGCTGACCTCTGGTGGCCGATCGGGGCACTGCA GGGGCCGAGCCATTTTGGGGGGCCCCCCTCCTTGCTCTGCAGGCACCTTAGTGGCTTTTT TCCTCCTGTGTACAGGGAAGAGAGGGGTACATTTCCCTGTGCTGACGGAAGCCAACTTGG CTTTCCCGGACTGCAAGCAGGGCTCTGCCCCAGAGGCCTCTCTCTCCGTCGTGGGAGAGA GACGTGTACATAGTGTAGGTCAGCGTGCTTAGCCTCCTGACCTGAGGCTCCTGTGCTACT TTGCCTTTTGCAAACTTTATTTTCATAGATTGAGAAGTTTTGTACAGAGAATTAAAAATG AAATTATTTATAATCTGGGTTTTGTGTCTTCAGCTGATGGATGTGCTGACTAGTGAGAGT GCTTGGGCCCTCCCCCAGCACCTAGGGAAAGGCTTCCCCTCCCCCTCCGGCCACAAGGTA CACAACTTTTAACTTAGCTCTTCCCGATGTTTGTTTGTTAGTGGGAGGAGTGGGGAGGGC TGGCTGTATGGCCTCCAGCCTACCTGTTCCCCCTGCTCCCAGGGCACATGGTTGGGCTGT GTCAACCCTTAGGGCCTCCATGGGGTCAGTTGTCCCTTCTCACCTCCCAGCTCTGTCCCC ATCAGGTCCCTGGGTGGCACGGGAGGATGGACTGACTTCCAGGACCTGTTGTGTGACAGG AGCTACAGCTTGGGTCTCCCTGCAAGAAGTCTGGCACGTCTCACCTCCCCCATCCCGGCC CCTGGTCATCTCACAGCAAAGAAGCCTCCTCCCTCCCGACCTGCCGCCACACTGGAGAGG GGGCACAGGGGCGGGGGAGGTTTCCTGTTCTGTGAAAGGCCGACTCCCTGACTCCATTCA TGCCCCCCCCCCCAGCCCCTCCCTTCATTCCCATTCCCCAACCTAAAGCCTGGCCCGGCT CCCAGCTGAATCTGGTCGGAATCCACGGGCTGCAGATTTTCCAAAACAATCGTTGTATCT TTATTGACTTTTTTTTTTTTTTTTTTCTGAATGCAATGACTGTTTTTTACTCTTAAGGAA AATAAACATCTTTTAGAAACAAAAAAAAAAAA |
Protein Sequence | >6720 : length: 1177 MDEPPFSEAALEQALGEPCDLDAALLTDIEGEVGAGRGRANGLDAPRAGADRGAMDCTFE DMLQLINNQDSDFPGLFDPPYAGSGAGGTDPASPDTSSPGSLSPPPATLSSSLEAFLSGP QAAPSPLSPPQPAPTPLKMYPSMPAFSPGPGIKEESVPLSILQTPTPQPLPGALLPQSFP APAPPQFSSTPVLGYPSPPGGFSTGSPPGNTQQPLPGLPLASPPGVPPVSLHTQVQSVVP QQLLTVTAAPTAAPVTTTVTSQIQQVPVLLQPHFIKADSLLLTAMKTDGATVKAAGLSPL VSGTTVQTGPLPTLVSGGTILATVPLVVDAEKLPINRLAAGSKAPASAQSRGEKRTAHNA IEKRYRSSINDKIIELKDLVVGTEAKLNKSAVLRKAIDYIRFLQHSNQKLKQENLSLRTA VHKSKSLKDLVSACGSGGNTDVLMEGVKTEVEDTLTPPPSDAGSPFQSSPLSLGSRGSGS GGSGSDSEPDSPVFEDSKAKPEQRPSLHSRGMLDRSRLALCTLVFLCLSCNPLASLLGAR GLPSPSDTTSVYHSPGRNVLGTESRDGPGWAQWLLPPVVWLLNGLLVLVSLVLLFVYGEP VTRPHSGPAVYFWRHRKQADLDLARGDFAQAAQQLWLALRALGRPLPTSHLDLACSLLWN LIRHLLQRLWVGRWLAGRAGGLQQDCALRVDASASARDAALVYHKLHQLHTMGKHTGGHL TATNLALSALNLAECAGDAVSVATLAEIYVAAALRVKTSLPRALHFLTRFFLSSARQACL AQSGSVPPAMQWLCHPVGHRFFVDGDWSVLSTPWESLYSLAGNPVDPLAQVTQLFREHLL ERALNCVTQPNPSPGSADGDKEFSDALGYLQLLNSCSDAAGAPAYSFSISSSMATTTGVD PVAKWWASLTAVVIHWLRRDEEAAERLCPLVEHLPRVLQESERPLPRAALHSFKAARALL GCAKAESGPASLTICEKASGYLQDSLATTPASSSIDKAVQLFLCDLLLVVRTSLWRQQQP PAPAPAAQGTSSRPQASALELRGFQRDLSSLRRLAQSFRPAMRRVFLHEATARLMAGASP TRTHQLLDRSLRRRAGPGGKGGAVAELEPRPTRREHAEALLLASCYLPPGFLSAPGQRVG MLAEAARTLEKLGDRRLLHDCQQMLMRLGGGTTVTSS |