| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3565 |
Name | IL4 |
Synonym | BCGF-1|BCGF1|BSF-1|BSF1|IL-4;interleukin 4;IL4;interleukin 4 |
Definition | B cell growth factor 1|B_cell stimulatory factor 1|binetrakin|interleukin 4 variant 2|interleukin-4|lymphocyte stimulatory factor 1|pitrakinra |
Position | 5q31.1 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Leishmaniasis;KEGG PATHWAY;hsa05140 |
Pathway | Allograft rejection;KEGG PATHWAY;hsa05330 |
Pathway | Glucocorticoid receptor regulatory network;PID Curated;200077 |
Pathway | il 4 signaling pathway;PID BioCarta;100127 |
Pathway | Cytokine-cytokine receptor interaction;KEGG PATHWAY;hsa04060 |
Pathway | IL12-mediated signaling events;PID Curated;200034 |
Pathway | IL2 signaling events mediated by STAT5;PID Curated;200158 |
Pathway | IL4-mediated signaling events;PID Curated;200018 |
Pathway | Calcium signaling in the CD4+ TCR pathway;PID Curated;200159 |
Pathway | T cell receptor signaling pathway;KEGG PATHWAY;hsa04660 |
Pathway | gata3 participate in activating the th2 cytokine genes expression;PID BioCarta;100157 |
Pathway | Hematopoietic cell lineage;KEGG PATHWAY;hsa04640 |
Pathway | CD40/CD40L signaling;PID Curated;200031 |
Pathway | Calcineurin-regulated NFAT-dependent transcription in lymphocytes;PID Curated;200039 |
Pathway | Notch signaling pathway;PID Curated;200013 |
Pathway | AP-1 transcription factor network;PID Curated;200118 |
Pathway | Intestinal immune network for IgA production;KEGG PATHWAY;hsa04672 |
Pathway | Jak-STAT signaling pathway;KEGG PATHWAY;hsa04630 |
Pathway | Fc epsilon RI signaling pathway;KEGG PATHWAY;hsa04664 |
Pathway | Asthma;KEGG PATHWAY;hsa05310 |
Pathway | the 41bb-dependent immune response;PID BioCarta;100257 |
Pathway | Interleukin signaling pathway;PANTHER;P00036 |
Pathway | Autoimmune thyroid disease;KEGG PATHWAY;hsa05320 |
Disease | atopy;GAD |
Disease | IL-4 production;GAD |
Disease | Purpura, Thrombocytopenic, Idiopathic;FunDO |
Disease | Oral cancer;FunDO |
Disease | malaria, plasmodium falciparum;GAD |
Disease | respiratory syncytial virus disease;GAD |
Disease | IMMUNE;GAD |
Disease | acute graft-versus-host disease;GAD |
Disease | INFECTION;GAD |
Disease | Colon cancer;FunDO |
Disease | Prostatic hypertrophy, Benign;FunDO |
Disease | asthma and IgE in childhood;GAD |
Disease | Stroke;FunDO |
Disease | Asthma. rhinitis;GAD |
Disease | multiple sclerosis;GAD |
Disease | Enteritis;FunDO |
Disease | Dermatitis;FunDO |
Disease | brucellosis;GAD |
Disease | Asthma. FEV1;GAD |
Disease | Grave`s disease;GAD |
Disease | Lupus erythematosus;FunDO |
Disease | Atopic asthma;GAD |
Disease | Lung cancer;FunDO |
Disease | Liver cancer;FunDO |
Disease | Malignant glioma;FunDO |
Disease | nephropathy;GAD |
Disease | spontaneous preterm birth;GAD |
Disease | Sinusitis;FunDO |
Disease | HIV;GAD |
Disease | Total IgE;GAD |
Disease | asthma. FEV(1);GAD |
Disease | diabetes, type 1;GAD |
Disease | Solid tumor;FunDO |
Disease | Kidney Failure, Chronic;GAD |
Disease | Crohn's disease;GAD |
Disease | Behcet syndrome;FunDO |
Disease | Squamous cell cancer;FunDO |
Disease | IGA glomerulonephritis;FunDO |
Disease | Abortion;FunDO |
Disease | Ovarian cancer;FunDO |
Disease | Allergies and autoimmune diseases;KEGG DISEASE |
Disease | leishmaniasis, cutaneous;GAD |
Disease | IL-4;GAD |
Disease | Atherosclerosis;FunDO |
Disease | pulmonary fibrosis;GAD |
Disease | Thyroid cancer;FunDO |
Disease | HEMATOLOGICAL;GAD |
Disease | IgE;GAD |
Disease | Bone metastases;FunDO |
Disease | Hyperglycemia;FunDO |
Disease | Asthma;FunDO |
Disease | Mucocutaneous lymph node syndrome;FunDO |
Disease | IgE, cord blood;GAD |
Disease | Prostate cancer;FunDO |
Disease | interstitial cystitis;GAD |
Disease | Infection;FunDO |
Disease | Leukemia;FunDO |
Disease | Schizophrenia;FunDO |
Disease | Pre-Eclampsia;FunDO |
Disease | tuberculosis;GAD |
Disease | Asthma;KEGG DISEASE;H00079 |
Disease | CARDIOVASCULAR;GAD |
Disease | rheumatoid arthritis;GAD |
Disease | atopic dermatitis;GAD |
Disease | Brucellosis;FunDO |
Disease | REPRODUCTION;GAD |
Disease | asthma IgE levels;GAD |
Disease | Immune system diseases;KEGG DISEASE |
Disease | Lymphoma;FunDO |
Disease | Temporal arteritis;FunDO |
Disease | Asthma. atopy;GAD |
Disease | Langerhans cell histiocytosis;GAD |
Disease | Periodontitis;FunDO |
Disease | Breast cancer;FunDO |
Disease | Increased IgE;GAD |
Disease | Embryoma;FunDO |
Disease | Systemic scleroderma;FunDO |
Disease | Rheumatoid arthritis;FunDO |
Disease | Ulcerative colitis;FunDO |
Disease | Asthma;GAD |
Disease | periodontitis;GAD |
Disease | Pancreas cancer;FunDO |
Disease | Epilepsy;FunDO |
Disease | Autoimmune disease;FunDO |
Disease | Diabetes mellitus;FunDO |
Disease | respiratory syncytial virus;GAD |
Disease | Alzheimer`s Disease;GAD |
Disease | Myocardial Infarction;GAD |
Disease | Kidney failure;FunDO |
Disease | giant cell arteritis;GAD |
Disease | Endometriosis;FunDO |
Disease | Asthma severity;GAD |
Disease | Hypothyroidism;FunDO |
Disease | Gouts;FunDO |
Disease | nephrotic syndrome;GAD |
Disease | minimal change nephrotic syndrome;GAD |
Disease | Fibromyalgia;GAD |
Disease | Hodgkin's disease;FunDO |
Disease | Helminthiasis;FunDO |
Disease | RENAL;GAD |
External Links | |
Links to Entrez Gene | 3565 |
Links to all GeneRIF Items | 3565 |
Links to iHOP | 3565 |
Sequence Information | |
Nucleotide Sequence | >3565 : length: 642 TGCATCGTTAGCTTCTCCTGATAAACTAATTGCCTCACATTGTCACTGCAAATCGACACC TATTAATGGGTCTCACCTCCCAACTGCTTCCCCCTCTGTTCTTCCTGCTAGCATGTGCCG GCAACTTTGTCCACGGACACAAGTGCGATATCACCTTACAGGAGATCATCAAAACTTTGA ACAGCCTCACAGAGCAGAAGACTCTGTGCACCGAGTTGACCGTAACAGACATCTTTGCTG CCTCCAAGAACACAACTGAGAAGGAAACCTTCTGCAGGGCTGCGACTGTGCTCCGGCAGT TCTACAGCCACCATGAGAAGGACACTCGCTGCCTGGGTGCGACTGCACAGCAGTTCCACA GGCACAAGCAGCTGATCCGATTCCTGAAACGGCTCGACAGGAACCTCTGGGGCCTGGCGG GCTTGAATTCCTGTCCTGTGAAGGAAGCCAACCAGAGTACGTTGGAAAACTTCTTGGAAA GGCTAAAGACGATCATGAGAGAGAAATATTCAAAGTGTTCGAGCTGAATATTTTAATTTA TGAGTTTTTGATAGCTTTATTTTTTAAGTATTTATATATTTATAACTCATCATAAAATAA AGTATATATAGAATCTAAAAAAAAAAAAAAAAAAAAAAAAAA |
Protein Sequence | >3565 : length: 153 MGLTSQLLPPLFFLLACAGNFVHGHKCDITLQEIIKTLNSLTEQKTLCTELTVTDIFAAS KNTTEKETFCRAATVLRQFYSHHEKDTRCLGATAQQFHRHKQLIRFLKRLDRNLWGLAGL NSCPVKEANQSTLENFLERLKTIMREKYSKCSS |