| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 1191 |
Name | CLU |
Synonym | AAG4|APO-J|APOJ|CLI|CLU1|CLU2|KUB1|NA1/NA2|SGP-2|SGP2|SP-40|TRPM-2|TRPM2;clusterin;CLU;clusterin |
Definition | aging-associated protein 4|apolipoprotein J|complement cytolysis inhibitor|complement lysis inhibitor|complement-associated protein SP-40,40|ku70-binding protein 1|sulfated glycoprotein 2|testosterone-repressed prostate message 2 |
Position | 8p21-p12 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Validated targets of C-MYC transcriptional repression;PID Curated;200171 |
Pathway | Hemostasis;Reactome;REACT:604 |
Disease | Lupus erythematosus;FunDO |
Disease | Alzheimer's disease;GAD |
Disease | Bladder cancer;FunDO |
Disease | Panic disorder;NHGRI |
Disease | carotid atherosclerosis;GAD |
Disease | Melanoma;FunDO |
Disease | Breast cancer;FunDO |
Disease | Esophagus cancer;FunDO |
Disease | Hypercholesterolemia;FunDO |
Disease | Von Hippel-Lindau syndrome;FunDO |
Disease | Prostate cancer;FunDO |
Disease | Serous cancer;FunDO |
Disease | Rheumatoid arthritis;FunDO |
Disease | panic disorder;GAD |
Disease | METABOLIC;GAD |
Disease | Kidney disease;FunDO |
Disease | Colon cancer;FunDO |
Disease | Alzheimer's disease;FunDO |
Disease | Larynx cancer;FunDO |
Disease | Nephrosis;FunDO |
Disease | Pre-Eclampsia;FunDO |
Disease | PSYCH;GAD |
Disease | Alzheimer's disease;NHGRI |
Disease | preeclampsia;GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | Endometrial cancer;FunDO |
Disease | hypertension;GAD |
Disease | NEUROLOGICAL;GAD |
Disease | Renal Cell cancer;FunDO |
Disease | Hypertension;FunDO |
Disease | cholesterol, LDL;GAD |
Disease | cholesterol;GAD |
Disease | Azoospermia;FunDO |
Disease | Ovarian cancer;FunDO |
Disease | Vascular disease;FunDO |
Disease | Atherosclerosis;FunDO |
External Links | |
Links to Entrez Gene | 1191 |
Links to all GeneRIF Items | 1191 |
Links to iHOP | 1191 |
Sequence Information | |
Nucleotide Sequence | >1191 : length: 3012 GGCAGGAACACTGGCAGGGCAGCCTGCTGTCGGCTTAGAGGGGATGGGCAGTGTGGAGGG CCTGGCAGAGCAAGAGGACTCATCCTTCCAAAGGGACTTTCTCTGGGAAGCCTGCTCCTC GGGCCACTGCGAACCCTCTCTACTCTCCGAAGGGAATTGTCCTTCCTGGCTTCCACTACT TCCACCCCTGAATGCACAGGCAGCCCGGCCCAAGTCTCCCACTAGGGATGCAGATGGATT CGGTGTGAAGGGCTGGCTGCTGTTGCCTCCGGCTCTTGAAAGTCAAGTTCAGAGGCGTGC AAAGACTCCAGAATTGGAGGCATGATGAAGACTCTGCTGCTGTTTGTGGGGCTGCTGCTG ACCTGGGAGAGTGGGCAGGTCCTGGGGGACCAGACGGTCTCAGACAATGAGCTCCAGGAA ATGTCCAATCAGGGAAGTAAGTACGTCAATAAGGAAATTCAAAATGCTGTCAACGGGGTG AAACAGATAAAGACTCTCATAGAAAAAACAAACGAAGAGCGCAAGACACTGCTCAGCAAC CTAGAAGAAGCCAAGAAGAAGAAAGAGGATGCCCTAAATGAGACCAGGGAATCAGAGACA AAGCTGAAGGAGCTCCCAGGAGTGTGCAATGAGACCATGATGGCCCTCTGGGAAGAGTGT AAGCCCTGCCTGAAACAGACCTGCATGAAGTTCTACGCACGCGTCTGCAGAAGTGGCTCA GGCCTGGTTGGCCGCCAGCTTGAGGAGTTCCTGAACCAGAGCTCGCCCTTCTACTTCTGG ATGAATGGTGACCGCATCGACTCCCTGCTGGAGAACGACCGGCAGCAGACGCACATGCTG GATGTCATGCAGGACCACTTCAGCCGCGCGTCCAGCATCATAGACGAGCTCTTCCAGGAC AGGTTCTTCACCCGGGAGCCCCAGGATACCTACCACTACCTGCCCTTCAGCCTGCCCCAC CGGAGGCCTCACTTCTTCTTTCCCAAGTCCCGCATCGTCCGCAGCTTGATGCCCTTCTCT CCGTACGAGCCCCTGAACTTCCACGCCATGTTCCAGCCCTTCCTTGAGATGATACACGAG GCTCAGCAGGCCATGGACATCCACTTCCATAGCCCGGCCTTCCAGCACCCGCCAACAGAA TTCATACGAGAAGGCGACGATGACCGGACTGTGTGCCGGGAGATCCGCCACAACTCCACG GGCTGCCTGCGGATGAAGGACCAGTGTGACAAGTGCCGGGAGATCTTGTCTGTGGACTGT TCCACCAACAACCCCTCCCAGGCTAAGCTGCGGCGGGAGCTCGACGAATCCCTCCAGGTC GCTGAGAGGTTGACCAGGAAATACAACGAGCTGCTAAAGTCCTACCAGTGGAAGATGCTC AACACCTCCTCCTTGCTGGAGCAGCTGAACGAGCAGTTTAACTGGGTGTCCCGGCTGGCA AACCTCACGCAAGGCGAAGACCAGTACTATCTGCGGGTCACCACGGTGGCTTCCCACACT TCTGACTCGGACGTTCCTTCCGGTGTCACTGAGGTGGTCGTGAAGCTCTTTGACTCTGAT CCCATCACTGTGACGGTCCCTGTAGAAGTCTCCAGGAAGAACCCTAAATTTATGGAGACC GTGGCGGAGAAAGCGCTGCAGGAATACCGCAAAAAGCACCGGGAGGAGTGAGATGTGGAT GTTGCTTTTGCACCTACGGGGGCATCTGAGTCCAGCTCCCCCCAAGATGAGCTGCAGCCC CCCAGAGAGAGCTCTGCACGTCACCAAGTAACCAGGCCCCAGCCTCCAGGCCCCCAACTC CGCCCAGCCTCTCCCCGCTCTGGATCCTGCACTCTAACACTCGACTCTGCTGCTCATGGG AAGAACAGAATTGCTCCTGCATGCAACTAATTCAATAAAACTGTCTTGTGAGCTGATCGC TTGGAGGGTCCTCTTTTTATGTTGAGTTGCTGCTTCCCGGCATGCCTTCATTTTGCTATG GGGGGCAGGCAGGGGGGATGGAAAATAAGTAGAAACAAAAAAGCAGTGGCTAAGATGGTA TAGGGACTGTCATACCAGTGAAGAATAAAAGGGTGAAGAATAAAAGGGATATGATGACAA GGTTGATCCACTTCAAGAATTGCTTGCTTTCAGGAAGAGAGATGTGTTTCAACAAGCCAA CTAAAATATATTGCTGCAAATGGAAGCTTTTCTGTTCTATTATAAAACTGTCGATGTATT CTGACCAAGGTGCGACAATCTCCTAAAGGAATACACTGAAAGTTAAGGAGAAGAATCAGT AAGTGTAAGGTGTACTTGGTATTATAATGCATAATTGATGTTTTCGTTATGAAAACATTT GGTGCCCAGAAGTCCAAATTATCAGTTTTATTTGTAAGAGCTATTGCTTTTGCAGCGGTT TTATTTGTAAAAGCTGTTGATTTCGAGTTGTAAGAGCTCAGCATCCCAGGGGCATCTTCT TGACTGTGGCATTTCCTGTCCACCGCCGGTTTATATGATCTTCATACCTTTCCCTGGACC ACAGGCGTTTCTCGGCTTTTAGTCTGAACCATAGCTGGGCTGCAGTACCCTACGCTGCCA GCAGGTGGCCATGACTACCCGTGGTACCAATCTCAGTCTTAAAGCTCAGGCTTTTCGTTC ATTAACATTCTCTGATAGAATTCTGGTCATCAGATGTACTGCAATGGAACAAAACTCATC TGGCTGCATCCCAGGTGTGTAGCAAAGTCCACATGTAAATTTATAGCTTAGAATATTCTT AAGTCACTGTCCCTTGTCTCTCTTTGAAGTTATAAACAACAAACTTAAAGCTTAGCTTAT GTCCAAGGTAAGTATTTTAGCATGGCTGTCAAGGAAATTCAGAGTAAAGTCAGTGTGATT CACTTAATGATATACATTAATTAGAATTATGGGGTCAGAGGTATTTGCTTAAGTGATCAT AATTGTAAAGTATATGTCACATTGTCACATTAATGTCACACTGTTTCAAAAGTTAAAAAA AAAAAAAAAAAA |
Protein Sequence | >1191 : length: 501 MQVCSQPQRGCVREQSAINTAPPSAHNAASPGGARGHRVPLTEACKDSRIGGMMKTLLLF VGLLLTWESGQVLGDQTVSDNELQEMSNQGSKYVNKEIQNAVNGVKQIKTLIEKTNEERK TLLSNLEEAKKKKEDALNETRESETKLKELPGVCNETMMALWEECKPCLKQTCMKFYARV CRSGSGLVGRQLEEFLNQSSPFYFWMNGDRIDSLLENDRQQTHMLDVMQDHFSRASSIID ELFQDRFFTREPQDTYHYLPFSLPHRRPHFFFPKSRIVRSLMPFSPYEPLNFHAMFQPFL EMIHEAQQAMDIHFHSPAFQHPPTEFIREGDDDRTVCREIRHNSTGCLRMKDQCDKCREI LSVDCSTNNPSQAKLRRELDESLQVAERLTRKYNELLKSYQWKMLNTSSLLEQLNEQFNW VSRLANLTQGEDQYYLRVTTVASHTSDSDVPSGVTEVVVKLFDSDPITVTVPVEVSRKNP KFMETVAEKALQEYRKKHREE |