Entrez Gene

Basic Information
Gene ID	990
Name	CDC6
Synonymous	cell division cycle 6;CDC6;cell division cycle 6
Definition	CDC6 cell division cycle 6 homolog\|CDC6-related protein\|cdc18-related protein\|cell division control protein 6 homolog\|cell division cycle 6 homolog\|p62(cdc6)
Position	17q21.3
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
Cdc6(h) --Caspase-3(h)--> protein remnants (processing)
Cdc6(h) --> Cdc6-p49(h) + protein remnants (cleavage)
Cdc6(h) --> Cdc6-p32(h) + protein remnants (cleavage)
cdc6(h) --> Cdc6(h) (expression).
Cdc6(h) --Caspase-3(h)--> Cdc6-p49(h) + protein remnants (cleavage)
Cdc6(h) --Caspase-3(h)--> Cdc6-p36(h) + protein remnants (cleavage)
Cdc6(h) --Caspase-7(h)--> Cdc6-p49(h) + protein remnants (cleavage)
Cdc6(h) --Caspase-7(h)--> Cdc6-p36(h) + protein remnants (cleavage)
Cdc6(h) + ATP --cyclinA(h):Cdk2(h)--> Cdc6(h){p} + ADP (phosphorylation)
Cdc6(h) --> Cdc6(h) (translocation)
Cdc6(h) --Caspase-3(h)--> Cdc6-p32(h) + protein remnants (cleavage)
Cdc6(h) + ATP --cyclinA(h):Cdk2(h)--> Cdc6(h){pS54} + ADP (phosphorylation)
Cdc6(h) + mcm2(h) <==> Cdc6(h):mcm2(h) (binding)
Fzr1(m.s.) + Cdc6(h) <==> Fzr1(m.s.):Cdc6(h) (binding)
Cdc20(m.s.) + Cdc6(h) <==> Cdc20(m.s.):Cdc6(h) (binding)
cdc6(h) --> Cdc6(h) (expression).
Cdc6(h) --> Cdc6(h) (translocation)

Location (AA)	PTM type	Literature	Database
Post Translational Modification [Top]
54	Phosphoserine (CDK2)	9889196;10339564	Phospho.ELM 6.0
74	Phosphoserine (CDK2)	9889196;10339564	Phospho.ELM 6.0
106	Phosphoserine (CDK2)	10339564	Phospho.ELM 6.0

Transcription Factors [Top]