| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 990 |
Name | CDC6 |
Synonym | CDC18L|HsCDC18|HsCDC6;cell division cycle 6;CDC6;cell division cycle 6 |
Definition | CDC6 cell division cycle 6 homolog|CDC6-related protein|cdc18-related protein|cell division control protein 6 homolog|cell division cycle 6 homolog|p62(cdc6) |
Position | 17q21.3 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | E2F transcription factor network;PID Curated;200027 |
Pathway | CDC6 association with the ORC:origin complex;PID Reactome;500388 |
Pathway | cdk regulation of dna replication;PID BioCarta;100110 |
Pathway | Cell Cycle Checkpoints;Reactome;REACT:1538 |
Pathway | Cell Cycle, Mitotic;Reactome;REACT:152 |
Pathway | Orc1 removal from chromatin;PID Reactome;500892 |
Pathway | Cell cycle;KEGG PATHWAY;hsa04110 |
Pathway | Association of licensing factors with the pre-replicative complex;PID Reactome;500987 |
Pathway | CDK-mediated phosphorylation and removal of Cdc6;PID Reactome;500925 |
Pathway | DNA Replication;Reactome;REACT:383 |
Disease | CANCER;GAD |
Disease | Pulmonary Disease, Chronic Obstructive;GAD |
Disease | Liver Neoplasms;GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | Carcinoma, Hepatocellular;GAD |
External Links | |
Links to Entrez Gene | 990 |
Links to all GeneRIF Items | 990 |
Links to iHOP | 990 |
Sequence Information | |
Nucleotide Sequence | >990 : length: 3136 GTAGATTCCCTCCCCCGTTCAGTGGTCGTGGCCTCACAGCGACTCTAAGACTTGGGGCTC TCTCATTGGCTGTAACTCTTCCACTGGATTGGTAGCAAAAAAAGAGGCGGTGCCCAAGGC GAAAGGCTCTGTGACTACAGCCAATCAGAATCGAGGCCGGGCTTTGGCGGGAGGTGGGAA CGCTGTGGCCATTCGGATTTGGCGCGAGCGCGGCTGGAGTTTGCTGCTGCCGCTGTGCAG TTTGTTCAGGGGCTTGTGGTGGTGAGTCCGAGAGGCTGCGTGTGAGAGACGTGAGAAGGA TCCTGCACTGAGGAGGTGGAAAGAAGAGGATTGCTCGAGGAGGCCTGGGGTCTGTGAGGC AGCGGAGCTGGGTGAAGGCTGCGGGTTCCGGCGAGGCCTGAGCTGTGCTGTCGTCATGCC TCAAACCCGATCCCAGGCACAGGCTACAATCAGTTTTCCAAAAAGGAAGCTGTCTCGGGC ATTGAACAAAGCTAAAAACTCCAGTGATGCCAAACTAGAACCAACAAATGTCCAAACCGT AACCTGTTCTCCTCGTGTAAAAGCCCTGCCTCTCAGCCCCAGGAAACGTCTGGGCGATGA CAACCTATGCAACACTCCCCATTTACCTCCTTGTTCTCCACCAAAGCAAGGCAAGAAAGA GAATGGTCCCCCTCACTCACATACACTTAAGGGACGAAGATTGGTATTTGACAATCAGCT GACAATTAAGTCTCCTAGCAAAAGAGAACTAGCCAAAGTTCACCAAAACAAAATACTTTC TTCAGTTAGAAAAAGTCAAGAGATCACAACAAATTCTGAGCAGAGATGTCCACTGAAGAA AGAATCTGCATGTGTGAGACTATTCAAGCAAGAAGGCACTTGCTACCAGCAAGCAAAGCT GGTCCTGAACACAGCTGTCCCAGATCGGCTGCCTGCCAGGGAAAGGGAGATGGATGTCAT CAGGAATTTCTTGAGGGAACACATCTGTGGGAAAAAAGCTGGAAGCCTTTACCTTTCTGG TGCTCCTGGAACTGGAAAAACTGCCTGCTTAAGCCGGATTCTGCAAGACCTCAAGAAGGA ACTGAAAGGCTTTAAAACTATCATGCTGAATTGCATGTCCTTGAGGACTGCCCAGGCTGT ATTCCCAGCTATTGCTCAGGAGATTTGTCAGGAAGAGGTATCCAGGCCAGCTGGGAAGGA CATGATGAGGAAATTGGAAAAACATATGACTGCAGAGAAGGGCCCCATGATTGTGTTGGT ATTGGACGAGATGGATCAACTGGACAGCAAAGGCCAGGATGTATTGTACACGCTATTTGA ATGGCCATGGCTAAGCAATTCTCACTTGGTGCTGATTGGTATTGCTAATACCCTGGATCT CACAGATAGAATTCTACCTAGGCTTCAAGCTAGAGAAAAATGTAAGCCACAGCTGTTGAA CTTCCCACCTTATACCAGAAATCAGATAGTCACTATTTTGCAAGATCGACTTAATCAGGT ATCTAGAGATCAGGTTCTGGACAATGCTGCAGTTCAATTCTGTGCCCGCAAAGTCTCTGC TGTTTCAGGAGATGTTCGCAAAGCACTGGATGTTTGCAGAAAGGAGGACTTGTTTCTCAG TGGGGAGCTCTGGATTTCCACCGTGTTAATGTCTGAAACATTATCAGTCCATTACCTACA GAGGGAGAAACAAATGAGATGTTGCTGGCACTCCCTGTGGAGAGCTATTGAAATTGTAGA GTCAGATGTCAAAAGCCAGACTATTCTCAAACCACTGTCTGAATGTAAATCACCTTCTGA GCCTCTGATTCCCAAGAGGGTTGGTCTTATTCACATATCCCAAGTCATCTCAGAAGTTGA TGGTAACAGGATGACCTTGAGCCAAGAAGGAGCACAAGATTCCTTCCCTCTTCAGCAGAA GATCTTGGTTTGCTCTTTGATGCTCTTGATCAGGCAGTTGAAAATCAAAGAGGTCACTCT GGGGAAGTTATATGAAGCCTACAGTAAAGTCTGTCGCAAACAGCAGGTGGCGGCTGTGGA CCAGTCAGAGTGTTTGTCACTTTCAGGGCTCTTGGAAGCCAGGGGCATTTTAGGATTAAA GAGAAACAAGGAAACCCGTTTGACAAAGGTGTTTTTCAAGATTGAAGAGAAAGAAATAGA ACATGCTCTGAAAGATAAAGCTTTAATTGGAAATATCTTAGCTACTGGATTGCCTTAAAT TCTTCTCTTACACCCCACCCGAAAGTATTCAGCTGGCATTTAGAGAGCTACAGTCTTCAT TTTAGTGCTTTACACATTCGGGCCTGAAAACAAATATGACCTTTTTTACTTGAAGCCAAT GAATTTTAATCTATAGATTCTTTAATATTAGCACAGAATAATATCTTTGGGTCTTACTAT TTTTACCCATAAAAGTGACCAGGTAGACCCTTTTTAATTACATTCACTACTTCTACCACT TGTGTATCTCTAGCCAATGTGCTTGCAAGTGTACAGATCTGTGTAGAGGAATGTGTGTAT ATTTACCTCTTCGTTTGCTCAAACATGAGTGGGTATTTTTTTGTTTGTTTTTTTTGTTGT TGTTGTTTTTGAGGCGCGTCTCACCCTGTTGCCCAGGCTGGAGTGCAATGGCGCGTTCTC TGCTCACTACAGCACCCGCTTCCCAGGTTGAAGTGATTCTCTTGCCTCAGCCTCCCGAGT AGCTGGGATTACAGGTGCCCACCACCGCGCCCAGCTAATTTTTTAATTTTTAGTAGAGAC AGGGTTTTACCATGTTGGCCAGGCTGGTCTTGAACTCCTGACCCTCAAGTGATCTGCCCA CCTTGGCCTCCCTAAGTGCTGGGATTATAGGCGTGAGCCACCATGCTCAGCCATTAAGGT ATTTTGTTAAGAACTTTAAGTTTAGGGTAAGAAGAATGAAAATGATCCAGAAAAATGCAA GCAAGTCCACATGGAGATTTGGAGGACACTGGTTAAAGAATTTATTTCTTTGTATAGTAT ACTATGTTCATGGTGCAGATACTACAACATTGTGGCATTTTAGACTCGTTGAGTTTCTTG GGCACTCCCAAGGGCGTTGGGGTCATAAGGAGACTATAACTCTACAGATTGTGAATATAT TTATTTTCAAGTTGCA |
Protein Sequence | >990 : length: 600 MPQTRSQAQATISFPKRKLSRALNKAKNSSDAKLEPTNVQTVTCSPRVKALPLSPRKRLG DDNLCNTPHLPPCSPPKQGKKENGPPHSHTLKGRRLVFDNQLTIKSPSKRELAKVHQNKI LSSVRKSQEITTNSEQRCPLKKESACVRLFKQEGTCYQQAKLVLNTAVPDRLPAREREMD VIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKKELKGFKTIMLNCMSLRTAQ AVFPAIAQEICQEEVSRPAGKDMMRKLEKHMTAEKGPMIVLVLDEMDQLDSKGQDVLYTL FEWPWLSNSHLVLIGIANTLDLTDRILPRLQAREKCKPQLLNFPPYTRNQIVTILQDRLN QVSRDQVLDNAAVQFCARKVSAVSGDVRKALDVCRKEDLFLSGELWISTVLMSETLSVHY LQREKQMRCCWHSLWRAIEIVESDVKSQTILKPLSECKSPSEPLIPKRVGLIHISQVISE VDGNRMTLSQEGAQDSFPLQQKILVCSLMLLIRQLKIKEVTLGKLYEAYSKVCRKQQVAA VDQSECLSLSGLLEARGILGLKRNKETRLTKVFFKIEEKEIEHALKDKALIGNILATGLP |