| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 9518 |
Name | GDF15 |
Synonymous | growth differentiation factor 15;GDF15;growth differentiation factor 15 |
Definition | NRG-1|NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1|NSAID-activated gene 1 protein|NSAID-regulated gene 1 protein|PTGF-beta|growth/differentiation factor 15|macrophage inhibitory cytokine 1|placental TGF-beta|placental bone morphogenetic |
Position | 19p13.11 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | MIC-1(h) --> ERK1(h){pT202}{pY204} (increase of phosphorylation) | MIC-1(h) --> ERK2(h){pT185}{pY187} (increase of phosphorylation) | MIC-1(h) --> AKT-1(h){pS473} (increase of phosphorylation) | GDF15(h) --> MIC-1(h) (expression). | GDF15(h) --> MIC-1(h) (expression). | p53(h) --> MIC-1(h) (increase of abundance) |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 70 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
There is no record for GDF15 | ||