| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 9510 |
Name | ADAMTS1 |
Synonymous | ADAM metallopeptidase with thrombospondin type 1 motif, 1;ADAMTS1;ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
Definition | A disintegrin and metalloproteinase with thrombospondin motifs 1|ADAM-TS 1|ADAM-TS1|ADAMTS-1|METH-1|a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1|human metalloproteinase with thrombospondin type 1 motifs |
Position | 21q21.2 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | VEGF-165(h) + ADAMTS-1(h) <==> VEGF-165(h):ADAMTS-1(h) (binding) | ADAMTS-1(h) + TFPI2(h) <==> ADAMTS-1(h):TFPI2(h) (binding) | ADAMTS-1(h) + TFPI2(h) <==> ADAMTS-1(h):TFPI2(h) (binding) | ADAMTS1(h) --> ADAMTS-1(h) (expression). | TFPI2(h) --ADAMTS-1(h)--> TFPI2-p6(h) + protein remnants (cleavage) | ADAMTS1(h) --> ADAMTS-1(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 547 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 720 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 764 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr21 |
Promoter: 27139099 - 27141099 | Agilent_014791 |
chr21 |
Promoter: 27139099 - 27141099 | GSE27584 |
chr21 |
Promoter: 27139099 - 27141099 | PMID:17167179 |
chr21 |
Promoter: 27139099 - 27141099 | PMID:16192589 |