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Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

846

Name

CASR

Synonymous

calcium-sensing receptor;CASR;calcium-sensing receptor

Definition

extracellular calcium-sensing receptor|parathyroid Ca(2+)-sensing receptor 1|parathyroid cell calcium-sensing receptor 1

Position

3q13

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

CASR(h) --> CaSR-isoform1(h) (expression).
mGluR1a(r) + CaSR(h) <==> mGluR1a(r):CaSR(h) (binding)
mGluR5(r) + CaSR(h) <==> mGluR5(r):CaSR(h) (binding)
CaSR(h) --> VDR(h) (increase of abundance)
CASR(h) --> CaSR(h) (expression).
CASR(h) --> CaSR-isoform2(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

90N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
130N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
261N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
287N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
386N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
400N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
446N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
468N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
488N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
541N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
594N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
888Phosphothreonine (PKC alpha;PK)9694886;12409307Phospho.ELM 6.0

Methylation Profile   [Top]

There is no record for CASR