Entrez Gene

Basic Information
Gene ID	831
Name	CAST
Synonymous	calpastatin;CAST;calpastatin
Definition	calpain inhibitor\|sperm BS-17 component
Position	5q15
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
calpastatin(h) + calmodulin(h) + calpain(h) + AR(h) <==> calpastatin(h):calmodulin(h):calpain(h):AR(h) (binding)
calpastatin(h) --> protein remnants (degradation)
CAST(h) --> calpastatin(h) (expression).
HCV-NS5A-1B-Japanese(HCV1BJapan) --> calpastatin(h) (increase of cleavage)
CAST(h) --> calpastatin-isoform1(h) (expression).
CAST(h) --> calpastatin-isoform2(h) (expression).
CAST(h) --> calpastatin-isoform3(h) (expression).
CAST(h) --> calpastatin-isoform4(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Translational Modification [Top]
222	Phosphoserine (By similarity).		Swiss-Prot 53.0
243	Phosphoserine.		Swiss-Prot 53.0
200	Phosphothreonine	1995645	Phospho.ELM 6.0
205	Phosphotyrosine	1995645	Phospho.ELM 6.0
243	Phosphoserine	15302935	Phospho.ELM 6.0

Transcription Factors [Top]