Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

831

Name

CAST

Synonymous

calpastatin;CAST;calpastatin

Definition

calpain inhibitor|sperm BS-17 component

Position

5q15

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1491C>A; p.F497L; 5:96757627-96757627

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.2014G>A; p.D672N; 5:96770591-96770591

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1349delA; p.E452fs*10; 5:96754695-96754695

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.204G>A; p.Q68Q; 5:96729695-96729695

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1654_1655delCT; p.S553fs*1; 5:96765257-96765258

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1415T>C; p.L472P; 5:96757463-96757463

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1138C>T; p.P380S; 5:96750611-96750611

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1018-6T>A; p.?; 5:96748512-96748512

 ovaryother; neoplasmUnknown

c.1018-6T>A; p.?; 5:96748512-96748512

 ovaryother; neoplasmUnknown

c.194C>T; p.S65L; 5:96729685-96729685

 skinmalignant_melanomaSubstitution - Missense

c.1202C>T; p.A401V; 5:96750675-96750675

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.995C>G; p.P332R; 5:96747370-96747370

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1868C>T; p.A623V; 5:96767914-96767914

 breastcarcinomaSubstitution - Missense

c.385-3C>T; p.?; 5:96737846-96737846

 skin; head_neckcarcinoma; squamous_cell_carcinomaUnknown

c.112C>T; p.H38Y; 5:96729201-96729201

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1282G>A; p.D428N; 5:96754132-96754132

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.900A>G; p.E300E; 5:96746356-96746356

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1157G>C; p.C386S; 5:96750630-96750630

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.1671A>G; p.G557G; 5:96765274-96765274

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.894T>A; p.A298A; 5:96746350-96746350

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - coding silent

c.1057G>A; p.D353N; 5:96748557-96748557

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1753C>T; p.L585F; 5:96766083-96766083

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1483G>A; p.E495K; 5:96757619-96757619

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.1893T>C; p.A631A; 5:96767939-96767939

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.63+1G>A; p.?; 5:96727531-96727531

 skin; facecarcinoma; squamous_cell_carcinomaUnknown

c.1636G>T; p.D546Y; 5:96765239-96765239

 livercarcinomaSubstitution - Missense

c.511G>T; p.E171*; 5:96740065-96740065

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.1636G>T; p.D546Y; 5:96765239-96765239

 livercarcinomaSubstitution - Missense

c.971A>G; p.D324G; 5:96747346-96747346

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1266G>T; p.K422N; 5:96754116-96754116

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.602C>A; p.S201*; 5:96740782-96740782

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.946G>A; p.E316K; 5:96746402-96746402

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.946G>A; p.E316K; 5:96746402-96746402

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.188C>T; p.S63F; 5:96729679-96729679

 skinmalignant_melanomaSubstitution - Missense

c.726A>T; p.S242S; 5:96741523-96741523

 oesophaguscarcinomaSubstitution - coding silent

c.733A>T; p.T245S; 5:96741530-96741530

 breastcarcinomaSubstitution - Missense

c.996A>G; p.P332P; 5:96747371-96747371

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.866C>T; p.S289L; 5:96742737-96742737

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.589C>T; p.P197S; 5:96740769-96740769

 NSmalignant_melanomaSubstitution - Missense

c.589C>T; p.P197S; 5:96740769-96740769

 NSmalignant_melanomaSubstitution - Missense

c.866C>T; p.S289L; 5:96742737-96742737

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1856C>G; p.S619*; 5:96767478-96767478

 breastcarcinomaSubstitution - Nonsense

c.648C>T; p.D216D; 5:96741310-96741310

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.48G>A; p.K16K; 5:96727515-96727515

 livercarcinomaSubstitution - coding silent

c.1269A>T; p.E423D; 5:96754119-96754119

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.48G>A; p.K16K; 5:96727515-96727515

 livercarcinomaSubstitution - coding silent

c.89C>T; p.S30F; 5:96729178-96729178

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.386C>T; p.S129L; 5:96737850-96737850

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.399T>G; p.A133A; 5:96737863-96737863

 skinmalignant_melanomaSubstitution - coding silent

c.541C>T; p.P181S; 5:96740095-96740095

 skinmalignant_melanomaSubstitution - Missense

c.1633C>A; p.L545I; 5:96765236-96765236

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.768A>C; p.K256N; 5:96741565-96741565

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.988C>T; p.L330L; 5:96747363-96747363

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.366G>A; p.P122P; 5:96736222-96736222

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1734A>C; p.K578N; 5:96766064-96766064

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1202C>G; p.A401G; 5:96750675-96750675

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1815+1G>C; p.?; 5:96766146-96766146

 kidneycarcinoma; clear_cell_renal_cell_carcinomaUnknown

c.562G>T; p.A188S; 5:96740116-96740116

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1635C>T; p.L545L; 5:96765238-96765238

 breastcarcinomaSubstitution - coding silent

c.1151C>T; p.A384V; 5:96750624-96750624

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.818C>T; p.S273L; 5:96742689-96742689

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.439G>T; p.E147*; 5:96737903-96737903

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.1330G>C; p.D444H; 5:96754676-96754676

 breastcarcinomaSubstitution - Missense

c.22-6A>G; p.?; 5:96727483-96727483

 livercarcinomaUnknown

c.767A>C; p.K256T; 5:96741564-96741564

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.22-6A>G; p.?; 5:96727483-96727483

 livercarcinomaUnknown

c.1701A>G; p.K567K; 5:96765304-96765304

 breastcarcinomaSubstitution - coding silent

c.1006G>A; p.E336K; 5:96747381-96747381

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.296C>T; p.S99F; 5:96730841-96730841

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.863G>A; p.R288H; 5:96742734-96742734

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1788C>T; p.Y596Y; 5:96766118-96766118

 oesophagus; middle_thirdcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1639G>T; p.D547Y; 5:96765242-96765242

 skin; armmalignant_melanomaSubstitution - Missense

c.245A>G; p.Q82R; 5:96730790-96730790

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.812C>T; p.A271V; 5:96742683-96742683

 skinmalignant_melanomaSubstitution - Missense

c.1894C>T; p.L632F; 5:96767940-96767940

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1038C>T; p.L346L; 5:96748538-96748538

 prostateadenomaSubstitution - coding silent

c.1718T>A; p.V573E; 5:96765321-96765321

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1718T>A; p.V573E; 5:96765321-96765321

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1498C>T; p.P500S; 5:96757634-96757634

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1498C>T; p.P500S; 5:96757634-96757634

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.109G>T; p.E37*; 5:96729198-96729198

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.1476T>C; p.A492A; 5:96757612-96757612

 salivary_glandcarcinoma; adenoid_cystic_carcinomaSubstitution - coding silent

c.603G>A; p.S201S; 5:96740783-96740783

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.603G>A; p.S201S; 5:96740783-96740783

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.1583C>T; p.T528M; 5:96762338-96762338

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - Missense

c.1583C>T; p.T528M; 5:96762338-96762338

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastoma; medullomyoblastomaSubstitution - Missense

c.161A>G; p.N54S; 5:96729652-96729652

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.422C>A; p.T141N; 5:96737886-96737886

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.602C>T; p.S201L; 5:96740782-96740782

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1609G>A; p.D537N; 5:96762364-96762364

 kidneyother; neoplasmSubstitution - Missense

c.461C>T; p.T154M; 5:96737925-96737925

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.461C>T; p.T154M; 5:96737925-96737925

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.461C>T; p.T154M; 5:96737925-96737925

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.461C>T; p.T154M; 5:96737925-96737925

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1025G>A; p.S342N; 5:96748525-96748525

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Missense

c.830G>A; p.G277D; 5:96742701-96742701

 livercarcinomaSubstitution - Missense

c.830G>A; p.G277D; 5:96742701-96742701

 livercarcinomaSubstitution - Missense

c.1018-6T>C; p.?; 5:96748512-96748512

 livercarcinomaUnknown

c.634G>A; p.A212T; 5:96741296-96741296

 central_nervous_system; braingliomaSubstitution - Missense

c.1018-6T>C; p.?; 5:96748512-96748512

 livercarcinomaUnknown

c.1379G>A; p.R460K; 5:96754725-96754725

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.629_630insAG; p.D211fs*29; 5:96741291-96741292

 large_intestine; coloncarcinoma; adenocarcinomaInsertion - Frameshift

c.1475C>T; p.A492V; 5:96757611-96757611

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.910G>A; p.E304K; 5:96746366-96746366

 breastcarcinomaSubstitution - Missense

c.1171T>A; p.C391S; 5:96750644-96750644

 breastcarcinomaSubstitution - Missense

c.1243T>G; p.L415V; 5:96754093-96754093

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.472C>T; p.P158S; 5:96737936-96737936

 skinmalignant_melanomaSubstitution - Missense