| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 7531 |
Name | YWHAE |
Synonymous | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon;YWHAE;tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon |
Definition | 14-3-3 epsilon|14-3-3 protein epsilon|epididymis luminal protein 2|mitochondrial import stimulation factor L subunit|protein kinase C inhibitor protein-1|tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide|tyrosine |
Position | 17p13.3 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | 14-3-3epsilon(h) + MLK2(h) <==> 14-3-3epsilon(h):MLK2(h) (binding) | 14-3-3epsilon(h) + MLK3(h) <==> 14-3-3epsilon(h):MLK3(h) (binding) | Cdc25B(h){p} + 14-3-3epsilon(h) <==> Cdc25B(h){p}:14-3-3epsilon(h) (binding) | Cdc25A(h) + 14-3-3epsilon(h) <==> Cdc25A(h):14-3-3epsilon(h) (binding) | 14-3-3epsilon(h) + Raf-1(h) <==> 14-3-3epsilon(h):Raf-1(h) (binding) | 14-3-3epsilon(h) + TBP(h) <==> 14-3-3epsilon(h):TBP(h) (binding). | TAF(II)31(h) + 14-3-3epsilon(h) <==> TAF(II)31(h):14-3-3epsilon(h) (binding). | p27Kip1(h){pS10}{pT187}{pT198} + 14-3-3epsilon(h) <==> p27Kip1(h){pS10}{pT187}{pT198}:14-3-3epsilon(h) (binding) | A20(h) + 14-3-3epsilon(h) <==> A20(h):14-3-3epsilon(h) (binding) | 14-3-3epsilon(h) + TFIIB(h) <==> 14-3-3epsilon(h):TFIIB(h) (binding). | 14-3-3epsilon(h) + Bax(h) <==> 14-3-3epsilon(h):Bax(h) (binding) | 14-3-3epsilon(h) + HCV-core(HCV) <==> 14-3-3epsilon(h):HCV-core(HCV) (binding) | HCV-Core-1B-Japanese(HCV1BJapan) + 14-3-3epsilon(h) <==> HCV-Core-1B-Japanese(HCV1BJapan):14-3-3epsilon(h) (binding) | 14-3-3epsilon(h) + HCV-core-1B(HCV1B) <==> 14-3-3epsilon(h):HCV-core-1B(HCV1B) (binding) | 14-3-3epsilon(h) + IRS-1(r) <==> 14-3-3epsilon(h):IRS-1(r) (binding) | 14-3-3epsilon(h) + ArgBP2(h) <==> 14-3-3epsilon(h):ArgBP2(h) (binding) | 14-3-3epsilon(h) + Grap2(h) <==> 14-3-3epsilon(h):Grap2(h) (binding) | 14-3-3epsilon(h) + GRIN2(h) <==> 14-3-3epsilon(h):GRIN2(h) (binding) | 14-3-3epsilon(h) + ASC1(h) <==> 14-3-3epsilon(h):ASC1(h) (binding) | 14-3-3epsilon(h) + POB1-isoform2(h) <==> 14-3-3epsilon(h):POB1-isoform2(h) (binding) | PMCA4(h) + 14-3-3epsilon(h) <==> PMCA4(h):14-3-3epsilon(h) (binding) | 14-3-3epsilon(h) + 14-3-3zeta(h) + alpha-tubulin 1B(h) + Hsp70-1(h) + QSK(h) <==> 14-3-3epsilon(h):14-3-3zeta(h):alpha-tubulin 1B(h):Hsp70-1(h):QSK(h) (binding) | 14-3-3epsilon(h) + 14-3-3zeta(h) + alpha-tubulin 1B(h) + Hsp70-1(h) + SIK(h) <==> 14-3-3epsilon(h):14-3-3zeta(h):alpha-tubulin 1B(h):Hsp70-1(h):SIK(h) (binding) | 14-3-3epsilon(h) + 14-3-3zeta(h) + alpha-tubulin 1B(h) + Hsp70-1(h) + mark1(h) <==> 14-3-3epsilon(h):14-3-3zeta(h):alpha-tubulin 1B(h):Hsp70-1(h):mark1(h) (binding) | 14-3-3epsilon(h) + 14-3-3zeta(h) + Hsp70-1(h) + MARK2(h) <==> 14-3-3epsilon(h):14-3-3zeta(h):Hsp70-1(h):MARK2(h) (binding) | 14-3-3epsilon(h) + 14-3-3zeta(h) + Hsp70-1(h) + CTAK1(m) <==> 14-3-3epsilon(h):14-3-3zeta(h):Hsp70-1(h):CTAK1(m) (binding) | 14-3-3epsilon(h) + 14-3-3zeta(h) + alpha-tubulin 1B(h) + Hsp70-1(h) + MARK4(h) <==> 14-3-3epsilon(h):14-3-3zeta(h):alpha-tubulin 1B(h):Hsp70-1(h):MARK4(h) (binding) | YWHAE(h) --> 14-3-3epsilon(h) (expression). | HDAC4(h) + 14-3-3epsilon(h) <==> HDAC4(h):14-3-3epsilon(h) (binding) | HDAC4(h){sumoK559} + 14-3-3epsilon(h) <==> HDAC4(h){sumoK559}:14-3-3epsilon(h) (binding) | 14-3-3epsilon(h) + HCV-Core-1B-Japanese(HCV1BJapan) <==> 14-3-3epsilon(h):HCV-Core-1B-Japanese(HCV1BJapan) (binding) | HCV-core(HCV) + 14-3-3epsilon(h) <==> HCV-core(HCV):14-3-3epsilon(h) (binding) | 14-3-3epsilon(h) + Rad(m) <==> 14-3-3epsilon(h):Rad(m) (binding) | 14-3-3epsilon(h) + Rem1(m) <==> 14-3-3epsilon(h):Rem1(m) (binding) | 14-3-3epsilon(h) + Kank(h) <==> 14-3-3epsilon(h):Kank(h) (binding) | YWHAE(h) --> 14-3-3epsilon(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 1 | N-acetylmethionine. | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr17 |
Promoter: 1249767 - 1251767 | Agilent_014791 |
chr17 |
Promoter: 1249767 - 1251767 | GSE27584 |
chr17 |
Promoter: 1249767 - 1251767 | Agilent_014791_44K |