| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 7531 |
Name | YWHAE |
Synonym | 14-3-3E|HEL2|KCIP-1|MDCR|MDS;tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon;YWHAE;tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon |
Definition | 14-3-3 epsilon|14-3-3 protein epsilon|epididymis luminal protein 2|mitochondrial import stimulation factor L subunit|protein kinase C inhibitor protein-1|tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide|tyrosine |
Position | 17p13.3 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | p75(NTR)-mediated signaling;PID Curated;200103 |
Pathway | Cell Cycle, Mitotic;Reactome;REACT:152 |
Pathway | Signalling by NGF;Reactome;REACT:11061 |
Pathway | Signaling events mediated by HDAC Class II;PID Curated;200019 |
Pathway | Parkinson disease;PANTHER;P00049 |
Pathway | Regulation of Telomerase;PID Curated;200072 |
Pathway | Neurotrophin signaling pathway;KEGG PATHWAY;hsa04722 |
Pathway | TGF-beta receptor signaling;PID Curated;200195 |
Pathway | Loss of proteins required for interphase microtubule organization from the centrosome;PID Reactome;500383 |
Pathway | EGF receptor signaling pathway;PANTHER;P00018 |
Pathway | Cell cycle;KEGG PATHWAY;hsa04110 |
Pathway | IGF1 pathway;PID Curated;200084 |
Pathway | Loss of Nlp from mitotic centrosomes;PID Reactome;500384 |
Pathway | Lissencephaly gene (LIS1) in neuronal migration and development;PID Curated;200114 |
Pathway | FGF signaling pathway;PANTHER;P00021 |
Pathway | NADE modulates death signalling;PID Reactome;500611 |
Pathway | Oocyte meiosis;KEGG PATHWAY;hsa04114 |
Disease | suicide;GAD |
Disease | PSYCH;GAD |
External Links | |
Links to Entrez Gene | 7531 |
Links to all GeneRIF Items | 7531 |
Links to iHOP | 7531 |
Sequence Information | |
Nucleotide Sequence | >7531 : length: 1860 TAGAGCTGAGCAGTTGTCCGCGTGCGCAGGCGGAAGTCCCGGATTGAGGCGCCGCCATTT TTGCTGCCCGGACGCGGAGCGAGAGGCTGAGAGAGTCGGAGACACTATCCGCTTCCATCC GTCGCGCAGACCCTGCCGGAGCCGCTGCCGCTATGGATGATCGAGAGGATCTGGTGTACC AGGCGAAGCTGGCCGAGCAGGCTGAGCGATACGACGTGCTCTGGAACTGAACCCGCAGTA TCTTCCAAGAAATGGTGGAGTCAATGAAGAAAGTAGCAGGGATGGATGTGGAGCTGACAG TTGAAGAAAGAAACCTCCTATCTGTTGCATATAAGAATGTGATTGGAGCTAGAAGAGCCT CCTGGAGAATAATCAGCAGCATTGAACAGAAAGAAGAAAACAAGGGAGGAGAAGACAAGC TAAAAATGATTCGGGAATATCGGCAAATGGTTGAGACTGAGCTAAAGTTAATCTGTTGTG ACATTCTGGATGTACTGGACAAACACCTCATTCCAGCAGCTAACACTGGCGAGTCCAAGG TTTTCTATTATAAAATGAAAGGGGACTACCACAGGTATCTGGCAGAATTTGCCACAGGAA ACGACAGGAAGGAGGCTGCGGAGAACAGCCTAGTGGCTTATAAAGCTGCTAGTGATATTG CAATGACAGAACTTCCACCAACGCATCCTATTCGCTTAGGTCTTGCTCTCAATTTTTCCG TATTCTACTACGAAATTCTTAATTCCCCTGACCGTGCCTGCAGGTTGGCAAAAGCAGCTT TTGATGATGCAATTGCAGAACTGGATACGCTGAGTGAAGAAAGCTATAAGGACTCTACAC TTATCATGCAGTTGTTACGTGATAATCTGACACTATGGACTTCAGACATGCAGGGTGACG GTGAAGAGCAGAATAAAGAAGCGCTGCAGGACGTGGAAGACGAAAATCAGTGAGACATAA GCCAACAAGAGAAACCATCTCTGACCACCCCCTCCTCCCCATCCCACCCTTTGGAAACTC CCCATTGTCACTGAGAACCACCAAATCTGACTTTTACATTTGGTCTCAGAATTTAGGTTC CTGCCCTGTTGGTTTTTTTTTTTTTTTTTTAAACAGTTTTCAAAAGTTCTTAAAGGCAAG AGTGAATTTCTGTGGATTTTACTGGTCCCAGCTTTTAGGTTCTTTAAGACACTAACAGGA CTACATAGAGGCTTTTTCAGCATTACTGTGTCGTCTCCGTGCCAGATGTGGCAAGATCAC CATTAGCAAATGGAAATTACATTTGAAAGCCATTAGACTTATAGGTGATGCAAGCATCTA AGAGAGAGGTTAATCACACTATAGAGGCATAAGTGGTATCAGTTTTCATTTTTCTAATTG TTTAAACTGTGTTTTATACCAGTGTTTGCAAGTAATTGGGTGTTAGCTTGAGATGGTTAA AGGTGGTTTGGGGAGGGACTTCGTTGTAATGGTTTTGCTGTAAAAAATGTTTCCAACTCC GCTGAAATGTTGCTGAAAAGCATGGTGCTGGTAACAGTTCAACAATCCGTGGCTGCTCAT TCTTGCCTACTTTACTCTCCCACTGAAGCAGGTTAGCGTTGAAGGTGGTATGGAAAAGCC TGCATGCCTGTTCAATTCTTTTGTTTCTTCTCCTTCCCCCTCCCCCTACCTCCTTCCCCT CACTCCTCCCCTCCTTCGCTCGCTCAACCTCTTTTGTTCAGTATGTGTAACTTGAAGCTA ATTTGTACTACTGGATATCTGACTGGAGCCACAGATACAGAATCTGTATTGTTCTTACTG AAACACAGCATGGAATTAACATTAAACTTAAATAAAACAAACCTAAATTAAAAATGCCAA |
Protein Sequence | >7531 : length: 255 MDDREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASW RIISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDILDVLDKHLIPAANTGESKVF YYKMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVF YYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGDGE EQNKEALQDVEDENQ |