Entrez Gene

Basic Information
Gene ID	7448
Name	VTN
Synonymous	vitronectin;VTN;vitronectin
Definition	S-protein\|complement S-protein\|epibolin\|serum spreading factor\|serum-spreading factor\|somatomedin B
Position	17q11
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
CD11B(m.s.):beta2-integrin(m.s.) + n vitronectin(h) <==> CD11B(m.s.):beta2-integrin(m.s.):(vitronectin(h))n (binding)
suPAR(m.s.) + vitronectin(h) <==> suPAR(m.s.):vitronectin(h) (binding)
vitronectin(h) + CD51(m.s.):beta5-integrin(m.s.) <==> vitronectin(h):CD51(m.s.):beta5-integrin(m.s.) (binding)
CD11B(m.s.):beta2-integrin(h) + vitronectin(h) <==> CD11B(m.s.):beta2-integrin(h):vitronectin(h) (binding)
CD11D(h):beta2-integrin(h) + vitronectin(h) <==> CD11D(h):beta2-integrin(h):vitronectin(h) (binding)
CD11D(m) + vitronectin(h) <==> CD11D(m):vitronectin(h) (binding)
vitronectin(h) + CD11D(h) <==> vitronectin(h):CD11D(h) (binding)
vitronectin(h) + CD11B(m) <==> vitronectin(h):CD11B(m) (binding)
VTN(h) --> vitronectin(h) (expression).
IGFBP-2(h) + vitronectin(h) <==> IGFBP-2(h):vitronectin(h) (binding)
VTN(h) --> vitronectin(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Translational Modification [Top]
69	Phosphothreonine; by CK2; in vitro.		Swiss-Prot 53.0
75	Sulfotyrosine (Probable).		Swiss-Prot 53.0
76	Phosphothreonine; by CK2; in vitro.		Swiss-Prot 53.0
78	Sulfotyrosine (Probable).		Swiss-Prot 53.0
86	N-linked (GlcNAc...).		Swiss-Prot 53.0
169	N-linked (GlcNAc...).		Swiss-Prot 53.0
171	Phosphoserine.		Swiss-Prot 53.0
242	N-linked (GlcNAc...).		Swiss-Prot 53.0
282	Sulfotyrosine (Potential).		Swiss-Prot 53.0
312	Phosphoserine.		Swiss-Prot 53.0
397	Phosphoserine (by PKA).		Swiss-Prot 53.0
417	Sulfotyrosine (Potential).		Swiss-Prot 53.0
420	Sulfotyrosine (Potential).		Swiss-Prot 53.0
171	Phosphoserine	17081983	Phospho.ELM 6.0

Transcription Factors [Top]