| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 7305 |
Name | TYROBP |
Synonymous | TYRO protein tyrosine kinase binding protein;TYROBP;TYRO protein tyrosine kinase binding protein |
Definition | DNAX-activation protein 12|KAR-associated protein|TYRO protein tyrosine kinase-binding protein|killer-activating receptor-associated protein |
Position | 19q13.1 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | NKAT5(h) + DAP12(h) <==> NKAT5(h):DAP12(h) (binding) | DAP12(h) <==> (DAP12(h))2 (oligomerization) | DAP12(h) + ATP --> DAP12(h){pY} + ADP (phosphorylation) | DAP12(h) + NKp44(h) <==> DAP12(h):NKp44(h) (binding) | TYROBP(h) --> DAP12(h) (expression). | TYROBP(h) --> DAP12-xbb1(h) (expression). | TYROBP(h) --> DAP12-xbb2(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 91 | Phosphotyrosine (Syk) | 9490415 | Phospho.ELM 6.0 | 102 | Phosphotyrosine (Syk) | 9490415 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr19 |
Promoter: 41090526 - 41092526 | GSE27584 |
chr19 |
Promoter: 41090526 - 41092526 | GSE27584 |