| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 7305 |
Name | TYROBP |
Synonymous | TYRO protein tyrosine kinase binding protein;TYROBP;TYRO protein tyrosine kinase binding protein |
Definition | DNAX-activation protein 12|KAR-associated protein|TYRO protein tyrosine kinase-binding protein|killer-activating receptor-associated protein |
Position | 19q13.1 |
Gene Type | protein-coding |
COSMIC somatic mutation [Top] | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.13G>T; p.E5*; 19:35908216-35908216 |
large_intestine | adenoma | Substitution - Nonsense |
c.138C>T; p.I46I; 19:35907537-35907537 |
large_intestine; rectum | carcinoma; adenocarcinoma | Substitution - coding silent |
c.266C>T; p.S89L; 19:35907228-35907228 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.296C>T; p.S99L; 19:35904615-35904615 |
NS | malignant_melanoma | Substitution - Missense |
c.121G>T; p.G41C; 19:35907554-35907554 |
liver | carcinoma | Substitution - Missense |
c.121G>T; p.G41C; 19:35907554-35907554 |
liver | carcinoma | Substitution - Missense |
c.207T>A; p.P69P; 19:35907468-35907468 |
lung; right_upper_lobe | carcinoma; adenocarcinoma | Substitution - coding silent |
c.202delG; p.V68fs*>46; 19:35907473-35907473 |
haematopoietic_and_lymphoid_tissue; spleen | lymphoid_neoplasm; marginal_zone_lymphoma | Deletion - Frameshift |
c.85G>A; p.A29T; 19:35907739-35907739 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.223G>A; p.A75T; 19:35907452-35907452 |
central_nervous_system; brain | primitive_neuroectodermal_tumour-medulloblastoma; medullomyoblastoma | Substitution - Missense |
c.223G>A; p.A75T; 19:35907452-35907452 |
central_nervous_system; brain | primitive_neuroectodermal_tumour-medulloblastoma | Substitution - Missense |
c.80C>A; p.A27D; 19:35907744-35907744 |
large_intestine; rectum | carcinoma; adenocarcinoma | Substitution - Missense |
c.75C>T; p.V25V; 19:35907749-35907749 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.252C>G; p.I84M; 19:35907242-35907242 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.45C>T; p.L15L; 19:35908184-35908184 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.226G>A; p.E76K; 19:35907449-35907449 |
skin | malignant_melanoma | Substitution - Missense |
c.225G>A; p.A75A; 19:35907450-35907450 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - coding silent |
c.43C>T; p.L15F; 19:35908186-35908186 |
skin; mucosal | malignant_melanoma | Substitution - Missense |
c.76C>T; p.Q26*; 19:35907748-35907748 |
lung | carcinoma; adenocarcinoma | Substitution - Nonsense |
c.304T>A; p.Y102N; 19:35904607-35904607 |
lung | carcinoma; small_cell_carcinoma | Substitution - Missense |
c.241A>G; p.K81E; 19:35907253-35907253 |
skin | malignant_melanoma | Substitution - Missense |
c.67C>T; p.R23C; 19:35907757-35907757 |
skin; scalp | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.277-1G>T; p.?; 19:35904635-35904635 |
large_intestine; colon | carcinoma; adenocarcinoma | Unknown |
c.104G>T; p.C35F; 19:35907571-35907571 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.65T>G; p.L22R; 19:35907759-35907759 |
skin | malignant_melanoma | Substitution - Missense |
c.208C>T; p.R70W; 19:35907467-35907467 |
skin | malignant_melanoma | Substitution - Missense |
c.95-1G>A; p.?; 19:35907581-35907581 |
lung | carcinoma; squamous_cell_carcinoma | Unknown |
c.28C>T; p.L10F; 19:35908201-35908201 |
skin | malignant_melanoma | Substitution - Missense |
c.233C>T; p.A78V; 19:35907261-35907261 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |