| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 7031 |
Name | TFF1 |
Synonymous | trefoil factor 1;TFF1;trefoil factor 1 |
Definition | breast cancer estrogen-inducible protein|breast cancer estrogen-inducible sequence|gastrointestinal trefoil protein pS2|polypeptide P1.A|protein pS2 |
Position | 21q22.3 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | TFF1(h) --/ Caspase-9(h) (inhibition) | TFF1(h) --> E2F(h) (activation) | TFF1(h) --> pRb(h) (activation) | TFF1(h) --> TFF1(h) (expression). | TFF1(h) + ubiquilin1(h) <==> TFF1(h):ubiquilin1(h) (binding) | p65PAK(h) --> TFF1(h) (increase of abundance) | p65PAK(m.s.) --> TFF1(h) (increase of abundance) | estradiol --> TFF1(h) (increase of abundance) | TFF1(h) --> TFF1(h) (expression). | TR4(m.s.) --/ TFF1(h) (decrease of abundance) | DP97(h) --/ TFF1(h) (decrease of abundance) | brca1(m.s.) --/ TFF1(h) (decrease of abundance) | cyclinD1(m.s.) --> TFF1(h) (increase of abundance) | AKT-2(m.s.) --> TFF1(h) (increase of abundance) |
|---|
Post Translational Modification [Top] | |||
There is no record for TFF1 | |||
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr21 |
Promoter: 42659213 - 42661213 | GoldenGate_Methylation_Cancer_Panel_I |
chr21 |
Promoter: 42659213 - 42661213 | GSE27584 |
chr21 |
Promoter: 42659213 - 42661213 | PMID:12379766 |
chr21 |
Promoter: 42659213 - 42661213 | PMID:15172987 |