Entrez Gene

Basic Information
Gene ID	7031
Name	TFF1
Synonymous	trefoil factor 1;TFF1;trefoil factor 1
Definition	breast cancer estrogen-inducible protein\|breast cancer estrogen-inducible sequence\|gastrointestinal trefoil protein pS2\|polypeptide P1.A\|protein pS2
Position	21q22.3
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.121T>A; p.C41S; 21:42363372-42363372	liver	carcinoma	Substitution - Missense
c.157A>C; p.N53H; 21:42363336-42363336	pancreas	pancreatic_intraepithelial_neoplasia_(PanIN)	Substitution - Missense
c.157A>C; p.N53H; 21:42363336-42363336	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.129T>C; p.F43F; 21:42363364-42363364	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.153_154delTG; p.A52fs*2; 21:42363339-42363340	liver	carcinoma; hepatocellular_carcinoma	Deletion - Frameshift
c.223G>A; p.D75N; 21:42363270-42363270	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.130C>T; p.P44S; 21:42363363-42363363	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.47C>T; p.S16F; 21:42366449-42366449	skin	malignant_melanoma	Substitution - Missense
c.117G>A; p.Q39Q; 21:42363376-42363376	skin	malignant_melanoma	Substitution - coding silent
c.174C>T; p.F58F; 21:42363319-42363319	skin	malignant_melanoma	Substitution - coding silent
c.174C>T; p.F58F; 21:42363319-42363319	skin	malignant_melanoma	Substitution - coding silent
c.231T>C; p.P77P; 21:42363262-42363262	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.131C>T; p.P44L; 21:42363362-42363362	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.76G>A; p.A26T; 21:42366420-42366420	skin	malignant_melanoma	Substitution - Missense
c.165C>A; p.G55G; 21:42363328-42363328	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.190G>T; p.G64W; 21:42363303-42363303	kidney	other; neoplasm	Substitution - Missense
c.46T>C; p.S16P; 21:42366450-42366450	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.46T>C; p.S16P; 21:42366450-42366450	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.148C>T; p.Q50*; 21:42363345-42363345	skin	malignant_melanoma	Substitution - Nonsense
c.6C>T; p.A2A; 21:42366490-42366490	skin	malignant_melanoma	Substitution - coding silent
c.49A>G; p.M17V; 21:42366447-42366447	urinary_tract; bladder	carcinoma	Substitution - Missense
c.36_37GG>AA; p.V13I; 21:42366459-42366460	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.60C>T; p.L20L; 21:42366436-42366436	cervix	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.195_196CC>TT; p.P66S; 21:42363297-42363298	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense

COSMIC somatic mutation [Top]