| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 633 |
Name | BGN |
Synonymous | biglycan;BGN;biglycan |
Definition | biglycan proteoglycan|bone/cartilage proteoglycan I|bone/cartilage proteoglycan-I|dermatan sulphate proteoglycan I|small leucine-rich protein 1A |
Position | Xq28 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | Biglycan(h) --TLL1(h)--> Biglycan-D38(h) + protein remnants (cleavage) | Biglycan(h) --BMP1(h)--> Biglycan-D38(h) + protein remnants (cleavage) | BGN(h) --> Biglycan(h) (expression). | BGN(h) --> Biglycan(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 42 | O-linked (Xyl...) (glycosaminoglycan). | Swiss-Prot 53.0 | 47 | O-linked (Xyl...) (glycosaminoglycan). | Swiss-Prot 53.0 | 180 | O-linked (Xyl...) (glycosaminoglycan)(Potential). | Swiss-Prot 53.0 | 198 | O-linked (Xyl...) (glycosaminoglycan)(Potential). | Swiss-Prot 53.0 | 270 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 311 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 42 | O-linked | Roughley, P.J. and White, R.J. (1989) Biochem. J., 262, 823-827. | OGlycBase6.0 | 47 | O-linked | Roughley, P.J. and White, R.J. (1989) Biochem. J., 262, 823-827. | OGlycBase6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chrX |
Promoter: 152412105 - 152414105 | GoldenGate_Methylation_Cancer_Panel_I |
chrX |
Promoter: 152412105 - 152414105 | GSE27584 |