Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

633

Name

BGN

Synonymous

biglycan;BGN;biglycan

Definition

biglycan proteoglycan|bone/cartilage proteoglycan I|bone/cartilage proteoglycan-I|dermatan sulphate proteoglycan I|small leucine-rich protein 1A

Position

Xq28

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.947G>A; p.G316D; 23:153508285-153508285

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.52C>T; p.P18S; 23:153504683-153504683

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.819G>T; p.L273L; 23:153507095-153507095

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.456G>C; p.E152D; 23:153505967-153505967

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.615C>T; p.F205F; 23:153506578-153506578

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.65G>A; p.R22K; 23:153504696-153504696

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.121G>A; p.A41T; 23:153504752-153504752

 endometriumcarcinoma; serous_carcinomaSubstitution - Missense

c.937A>G; p.T313A; 23:153508275-153508275

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.574G>A; p.G192R; 23:153506537-153506537

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.955G>A; p.D319N; 23:153508293-153508293

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1027C>T; p.P343S; 23:153508365-153508365

 skinmalignant_melanomaSubstitution - Missense

c.884G>C; p.G295A; 23:153507160-153507160

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.114T>C; p.D38D; 23:153504745-153504745

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.300C>T; p.N100N; 23:153505299-153505299

 pancreascarcinomaSubstitution - coding silent

c.47C>A; p.A16D; 23:153504678-153504678

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.138C>A; p.T46T; 23:153504769-153504769

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.797G>C; p.R266T; 23:153507073-153507073

 breastcarcinoma; ductal_carcinomaSubstitution - Missense

c.796A>T; p.R266W; 23:153507072-153507072

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.170C>T; p.P57L; 23:153504801-153504801

 central_nervous_system; braingliomaSubstitution - Missense

c.910-1G>A; p.?; 23:153508247-153508247

 skinmalignant_melanomaUnknown

c.310G>A; p.E104K; 23:153505309-153505309

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.310G>A; p.E104K; 23:153505309-153505309

 thyroidcarcinomaSubstitution - Missense

c.42C>T; p.S14S; 23:153504673-153504673

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1058G>A; p.R353H; 23:153508396-153508396

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1020C>T; p.N340N; 23:153508358-153508358

 livercarcinomaSubstitution - coding silent

c.907C>T; p.Q303*; 23:153507183-153507183

 lungcarcinoma; adenocarcinomaSubstitution - Nonsense

c.1020C>T; p.N340N; 23:153508358-153508358

 livercarcinomaSubstitution - coding silent

c.377T>A; p.I126N; 23:153505888-153505888

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.919C>G; p.L307V; 23:153508257-153508257

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.515G>A; p.R172H; 23:153506026-153506026

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.141G>C; p.S47S; 23:153504772-153504772

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.771-1G>A; p.?; 23:153507046-153507046

 skinmalignant_melanomaUnknown

c.502G>A; p.D168N; 23:153506013-153506013

 skinmalignant_melanomaSubstitution - Missense

c.316C>T; p.R106C; 23:153505315-153505315

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.494G>A; p.R165H; 23:153506005-153506005

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.231C>T; p.S77S; 23:153504862-153504862

 livercarcinomaSubstitution - coding silent

c.181G>C; p.A61P; 23:153504812-153504812

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.718A>T; p.K240*; 23:153506871-153506871

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.63G>A; p.Q21Q; 23:153504694-153504694

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.999C>T; p.N333N; 23:153508337-153508337

 livercarcinomaSubstitution - coding silent

c.999C>T; p.N333N; 23:153508337-153508337

 livercarcinomaSubstitution - coding silent

c.142G>T; p.G48C; 23:153504773-153504773

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.480C>T; p.S160S; 23:153505991-153505991

 skinmalignant_melanomaSubstitution - coding silent

c.640C>T; p.R214C; 23:153506603-153506603

 lung; middle_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.389A>G; p.H130R; 23:153505900-153505900

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.733G>A; p.E245K; 23:153506886-153506886

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.733G>A; p.E245K; 23:153506886-153506886

 skinmalignant_melanomaSubstitution - Missense

c.733G>A; p.E245K; 23:153506886-153506886

 pancreascarcinomaSubstitution - Missense

c.926C>A; p.S309Y; 23:153508264-153508264

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.4T>C; p.W2R; 23:153504635-153504635

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.7C>T; p.P3S; 23:153504638-153504638

 skinmalignant_melanomaSubstitution - Missense

c.954C>T; p.N318N; 23:153508292-153508292

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.864G>T; p.K288N; 23:153507140-153507140

 breastcarcinoma; ductal_carcinomaSubstitution - Missense

c.805G>A; p.E269K; 23:153507081-153507081

 biliary_tract; bile_ductcarcinoma; adenocarcinomaSubstitution - Missense

c.1046C>T; p.P349L; 23:153508384-153508384

 skinmalignant_melanomaSubstitution - Missense

c.266C>T; p.S89F; 23:153505265-153505265

 skinmalignant_melanomaSubstitution - Missense

c.1046C>T; p.P349L; 23:153508384-153508384

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.24_25GT>TA; p.S9T; 23:153504655-153504656

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.616G>A; p.D206N; 23:153506579-153506579

 thyroidcarcinomaSubstitution - Missense

c.214C>A; p.R72R; 23:153504845-153504845

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1023C>T; p.P341P; 23:153508361-153508361

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.975C>T; p.F325F; 23:153508313-153508313

 central_nervous_system; braingliomaSubstitution - coding silent

c.375G>A; p.K125K; 23:153505886-153505886

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.298A>G; p.N100D; 23:153505297-153505297

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.540C>T; p.S180S; 23:153506051-153506051

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.434T>C; p.I145T; 23:153505945-153505945

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.854_856delACA; p.N287delN; 23:153507130-153507132

 endometriumcarcinoma; endometrioid_carcinomaDeletion - In frame

c.770G>T; p.R257M; 23:153506923-153506923

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.309C>T; p.S103S; 23:153505308-153505308

 breastcarcinomaSubstitution - coding silent

c.514_515delCG; p.R172fs*29; 23:153506025-153506026

 lungcarcinoma; adenocarcinomaDeletion - Frameshift

c.798G>T; p.R266S; 23:153507074-153507074

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.412C>T; p.R138W; 23:153505923-153505923

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.412C>T; p.R138W; 23:153505923-153505923

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1047G>A; p.P349P; 23:153508385-153508385

 breastcarcinomaSubstitution - coding silent

c.1100A>G; p.K367R; 23:153508438-153508438

 pleurapulmonary_blastomaSubstitution - Missense

c.515delG; p.R172fs*14; 23:153506026-153506026

 lungcarcinoma; adenocarcinomaDeletion - Frameshift

c.751C>T; p.R251C; 23:153506904-153506904

 skinmalignant_melanomaSubstitution - Missense

c.751C>T; p.R251C; 23:153506904-153506904

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.980T>G; p.V327G; 23:153508318-153508318

 breastcarcinomaSubstitution - Missense

c.564C>T; p.I188I; 23:153506075-153506075

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.509G>A; p.R170H; 23:153506020-153506020

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.509G>A; p.R170H; 23:153506020-153506020

 breastcarcinomaSubstitution - Missense

c.504C>T; p.D168D; 23:153506015-153506015

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.504C>T; p.D168D; 23:153506015-153506015

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent