| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 6272 |
Name | SORT1 |
Synonymous | sortilin 1;SORT1;sortilin 1 |
Definition | 100 kDa NT receptor|NTR3|glycoprotein 95|neurotensin receptor 3|sortilin |
Position | 1p13.3|1p21.3-p13.1 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | sortilin(h) --PACE(h)--> protein remnants + sortilin-A78(h) (processing) | Cdk2(h) + sortilin(h) <==> Cdk2(h):sortilin(h) (binding) | SORT1(h) --> sortilin(h) (expression). | sortilin(h) + BDNF(h) <==> sortilin(h):BDNF(h) (binding) | sortilin(h) + BDNF(m) <==> sortilin(h):BDNF(m) (binding) | BDNF(m) + sortilin(h) <==> BDNF(m):sortilin(h) (binding) | SORT1(h) --> sortilin(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 98 | N-linked (GlcNAc...) (Probable). | Swiss-Prot 53.0 | 162 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 274 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 406 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 582 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 684 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr1 |
Promoter: 109741586 - 109743586 | Agilent_014791 |
chr1 |
Promoter: 109741586 - 109743586 | GSE27584 |
chr1 |
Promoter: 109741586 - 109743586 | Agilent_014791_44K |