| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 6272 |
Name | SORT1 |
Synonym | Gp95|LDLCQ6|NT3;sortilin 1;SORT1;sortilin 1 |
Definition | 100 kDa NT receptor|NTR3|glycoprotein 95|neurotensin receptor 3|sortilin |
Position | 1p13.3|1p21.3-p13.1 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Membrane Trafficking;Reactome;REACT:11123 |
Pathway | Lysosome;KEGG PATHWAY;hsa04142 |
Pathway | p75(NTR)-mediated signaling;PID Curated;200103 |
Pathway | Neurotrophin signaling pathway;KEGG PATHWAY;hsa04722 |
Disease | myocardial infarction (early onset);GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | LDL cholesterol;GAD |
Disease | Low density lipoprotein cholesterol level QTL6;OMIM |
Disease | Blood lipid traits;NHGRI |
Disease | METABOLIC;GAD |
External Links | |
Links to Entrez Gene | 6272 |
Links to all GeneRIF Items | 6272 |
Links to iHOP | 6272 |
Sequence Information | |
Nucleotide Sequence | >6272 : length: 7051 TTCCAATACTTGGCCTCTCTTCATCCTACCTTCCCTAGCACCCCCAGCCGTCTAGCTTAT TTAATAGTCTCTTGAGTTCTGTTTCTTCCATTCAGCTTTGGATCAAGGAGTAGGAACTCT GTAGGATCTCCTTCTTGGTCCTGGTTGAGCAGAGTGAGCGAAACCTTCATGAAGAGTCTT CTCTCATGCAATGTATAGTCAGACCTTTAGCCCCTAGAGGGATGTTAAAATGACTTATGC ATTGGATATTTCAGTAAGAAGTATCAGCAGATTTGATGAAGTGTAATTTATCTGGGGAAA GGTTAGTCTTCATCTGAAGTTTGGTTGGGATGAGAGTAGAAAGCTAGCCAGGTATGACAG ATGGCTCCAAGGGAATGCAGTGTTAACAATTAGCATGTGTTTGATGATCTCAGAGGCTCA GTATCCTTGTCCTGGGTTGGAGATAGCACTGGGGTCATTCTAGTCTTGACTACCTTCCAT GTACCACTGGTAATTATGACTTTTGGACAGTCCAAGCTATATCGAAGTGAGGATTATGGG AAGAACTTTAAGGATATTACAGATCTCATCAATAACACCTTTATTCGGACTGAATTTGGC ATGGCTATTGGTCCTGAGAACTCTGGAAAGGTGGTGTTAACAGCAGAGGTGTCTGGAGGA AGTCGTGGAGGAAGAATCTTTAGATCATCAGATTTTGCGAAGAATTTTGTGCAAACAGAT CTCCCTTTTCATCCTCTCACTCAGATGATGTATAGCCCTCAGAATTCTGATTATCTTTTA GCTCTCAGCACTGAAAATGGCCTGTGGGTGTCCAAGAATTTTGGGGGAAAATGGGAAGAA ATCCACAAAGCAGTATGTTTGGCCAAATGGGGATCAGACAACACCATCTTCTTTACAACC TATGCAAATGGCTCCTGCAAAGCTGACCTTGGGGCTCTGGAATTATGGAGAACTTCAGAC TTGGGAAAAAGCTTCAAAACTATTGGTGTGAAAATCTACTCATTTGGTCTTGGGGGACGT TTCCTTTTTGCCTCTGTGATGGCTGATAAGGATACAACAAGAAGGATCCACGTTTCAACA GATCAAGGGGACACATGGAGCATGGCCCAGCTCCCCTCCGTGGGACAGGAACAGTTCTAT TCTATTCTGGCAGCAAATGATGACATGGTATTCATGCATGTAGATGAACCTGGAGACACT GGGTTTGGCACAATCTTTACCTCAGATGATCGAGGCATTGTCTATTCCAAGTCTTTGGAC CGACATCTCTACACTACCACAGGCGGAGAGACGGACTTTACCAACGTGACCTCCCTCCGC GGCGTCTACATAACAAGCGTGCTCTCCGAAGATAATTCTATCCAGACCATGATCACTTTT GACCAAGGAGGAAGGTGGACGCACCTGAGGAAGCCTGAAAACAGTGAATGTGATGCTACA GCAAAAAACAAGAATGAGTGCAGCCTTCATATTCATGCTTCCTACAGCATCTCCCAGAAA CTGAATGTTCCAATGGCCCCACTCTCAGAGCCGAATGCCGTAGGCATTGTCATTGCTCAT GGTAGCGTGGGGGATGCCATCTCAGTGATGGTTCCAGATGTGTACATCTCAGATGATGGG GGTTACTCCTGGACAAAGATGCTGGAAGGACCCCACTATTACACCATCCTGGATTCTGGA GGCATCATTGTGGCCATTGAGCACAGCAGCCGTCCTATCAATGTGATTAAGTTCTCCACA GACGAAGGTCAATGCTGGCAAACCTACACGTTCACCAGGGACCCCATCTATTTCACTGGC CTAGCTTCAGAACCTGGAGCTAGGTCCATGAATATCAGCATTTGGGGCTTCACAGAATCT TTCCTGACCAGCCAGTGGGTCTCCTACACCATTGATTTTAAAGATATCCTTGAAAGGAAC TGTGAAGAGAAGGACTATACCATATGGCTGGCACACTCCACAGACCCTGAAGATTATGAA GATGGCTGCATTTTGGGCTACAAAGAACAGTTTCTGCGGCTACGCAAGTCATCCGTGTGT CAGAATGGTCGAGACTATGTTGTGACCAAGCAGCCCTCCATCTGCCTCTGTTCCCTGGAG GACTTTCTCTGTGATTTTGGCTACTACCGTCCAGAAAATGACTCCAAGTGTGTGGAACAG CCAGAACTGAAGGGCCACGACCTGGAGTTTTGTCTGTACGGAAGAGAAGAACACCTAACA ACAAATGGGTACCGGAAAATTCCAGGGGACAAATGCCAGGGTGGGGTAAATCCAGTTCGA GAAGTAAAAGACTTGAAAAAGAAATGCACAAGCAACTTTTTGAGTCCGGAAAAACAGAAT TCCAAGTCAAATTCTGTTCCAATTATCCTGGCCATCGTGGGATTGATGCTGGTCACAGTC GTAGCAGGAGTGCTCATTGTGAAGAAATATGTCTGTGGGGGAAGGTTCCTGGTGCATCGA TACTCTGTGCTGCAGCAGCATGCAGAGGCCAATGGTGTGGATGGTGTGGATGCTTTGGAC ACAGCCTCCCACACTAATAAAAGTGGTTATCATGATGACTCAGATGAGGACCTCTTGGAA TAGCTCTTCAGAGGAGCTGGACCCAGCATGGATGGTGGAACCACAGTACCTCTTACACTC CCTGTGGCTCCAACTTCAGGAAATAAATTTCCCATTGCGAGGGACCCAGCTCTGTTTCTG CTGCTTCCATCAAAGCCAAAAGGACCTACACTAAAGAAATGCAGGGTGGGGGTGGGGAAC CCTGAGCACTTTTTTACAATTGGCTCTGAGAAAAAGGGAGACATTTTAAATTCTTTAACT TCTTATTTCTCGTCCTGTCTCTTTGCAAAGTATGGGCTTTTTTGTTTTTGTTTTTTAAGG GAAACGAAATGGAATTCGAAGGGACCTTTTCACTAACCCCACTTCTGTGTGTTCTGCATG GCGCCTGCCCCAGGGCATCTGCCAACTCCAGTATCAGCTCTCACAGTGTACTTGGTACCA TCCCTGGGCTCTGCTGGCGAGACGAAACAGCTGTAGAGATGAAAACAGGCTGCAGAGGCT GGCACAGCCTGGCCGGCTTTTCTCCATCTGGGGACAGTCCTACTCCAAGAACACTGCACA CCAGCTCCTCACACAGATCCCACTTACTCTTTTTTTTTTTTTCAGAGACCACAGACCACA GTGATTTTTCTTTTCCCTTGTTTAATTAGGCAATACCCTTGTTAATTGCCCTTTGGCAAC TAACTTAACCATGTGCTTCCCACACAGTACATCAGGAAAACTTACAGGGCAATATTTTTA ACTTGGGGCAGGAAGAAGGGAGCAGCAGAGAATTGACTAGATATAGCACCTATTAAAAGA GAACTCTTGCTTCTTCTGAGATTTTTCAAGCTGTGCTTTGTGTGTGTGCCAGTAGACTTA CGCAAGGACAGGGTACAAACTTAGCTGGAAGTCTGCCCAGGCTGAATGATCTCTTCCCTA GAGTTGATTGTCGGGTACACAGTGTGAACCCCCGAAGACGGAACCTCACAGTCTTCCATG TTCCCTTCTTAACTGTCGTGTGGCTCGTTGCTAAATCATGACAATGGCTGCCTATCTGCT GCTTCTTAGGTTGCTGTTGTACATGGAACCAGGACTAGAGATTTTTTCAGATTTATAGAC TTAAAAAATTAGAATTTTATTACCAGGCTTTCCTTCTCACCCCTTTTTTCTGACTTTGCC AAGTAATTTGTTGACACGAAAATTTTGGAGGAACCAATTGAAAACACACTTCCAGTCTAG ATGATGCTTTGTGTGATACATTAAGTTCTTATTTTGGATTAAAAGAAGTTTTCCATTTGA TACCTCTCTAAATTAAATAAATTATAGAATGTAGTTGGGTGGATTTTGGGGTGGCCATAT AGTAATGGAAAGCTGCAATAATTAGTTTTAATACAGCTTGAATATTTGCTATATAGAAAT ATAGTATGGAAAGTTTTTGGTCTTAATGTAGCTACTGTGCGGGTCACAGTTTCTCCCAAT GATTATGACTGGGACATTCTTTGGTAGATACCATTTGCTACTAGTTTATTTTGTGGCTAG AAAGTCAGTTTTGTGTGTTTTTTTTTTTTTTTATTTGAAGTGCCAAATTAACTTTAGTCA GAATGTGAGCAGATGGCTAAGTTCTCTCCTCCCCAGAATGGATTAACAGCTGCGTGGAAA GTGGGGGAGAGAGTGGATGGAGACTTTTAGAGATGTTAAAACTGCAGTAGAATGAAATGA GTCAGGGAGCTTCAGTTAGAAAATAAAGTTGAGGCAGTTTTTGTGAAGATAATATGGTTA GGGCTGGAGTGCACTAGTCTTTTTGCTTATTCATTTTGCATGGTTTTAAAATTAAAAATA ATTCCGAAGATACACCAGCTCACAAATGAAAACGTCAGCCTCTGCCCCACCCTCCCTCCT GCCCAAAGTGAATTTGGTACTCAGAAAAGAACTGTTTATACCACTCACCTTTCTCCCAGC ATGTACTCACTGTGGGCAGATGCACCAATACATGGTAATCCTCTTACTCATTTTAAGACG TAGGAAACTCAATATTCTTCTCTAACCATATACGATAGGGCTCTTCGCTTTTAATGATAT CTGGGATTTCTGTGGAACTTGGCAAATTTTCAGAGCACCTTCACTCACATAATGTCATTT GAACCTCACAATGTTCTTGGGATGGAGTCAGTTGTTCAGGGTCCCCGTGTGTGTGATAAG CAGTGCTGGCTGGCTGTCTTCAGAACTCTTGGAAATCTTTACACATGCGAGTGCTAACCA CTTTGAGCAAGGCTGCCTTCTTGTAGATGACTTGCTGTTCTTTATGACAGGGATCAGTGG CATTTGTTTCCTAGCAGTATTTAGCACCTTTTTGCCACCTTGGTGAACAGAAAATTGTAT TTTCCTGTCTTTCATGGCTGAAAACAAAAGTAATGGGAATTTTAAATACGTTTGCAGAAA CTGCCCCTCCCCTCATTGAGGGTCACTGCTCAAGAGTGCAGGAGTGGACTCTCCACTGAT GGGTCTCCCTCCCCATCCTGGTTTCCACCCCGGGCTGGCTAGCTCTGTTGGTTTGAAGAC TGACAGCCAGCCTGGCTCATTCTCATTATTGGCTAGTTAGCTTTCTTTATCAACCTGCTC ACTCACAAATGTGTGCCCTCAGCCAGAGAGTAAGAAAGCCCAAATCTGTTACAGCTTCTA AAAAAATAGATTTCTAATTTGTCCTACTCATGTTAGGAGCATTATCTTTGAAGGTAAAAC ATAGTGTATCATTGTGTAAACTCCCAGGCTTGATGTAGCAGAAGAGATCATTTCTGGAGG CTTCAGCAATGGAATTTAGCATTATAAGAGAGATTGGACAAACCAGTCCAAAGTGGTCCG AGTTCTTAAATCCAGGTAGGGAACTCACTCTTCTTTCTTCTCTGGACCTAATTGGGCATT GGGCTTTAGTGAGACCACAGACCAGGCCCGTCTCTCCTGTAGGCTTTTAATTCAATGGCA ACTCTATTTCAAAGAATAAAAGCCTTTGGAGAGTTGCGGCAGTTCTGGGGGCGGGCTCAG GAGAGTCCATAGATCAGCCGTAACTGGAACGTAGAATCTACGTCTGCCTCTGAATGGACT TCCCACCTCCTCTCTCTTGCTCTGATGCTTGCCTCTGGGCCTCTCCATGCCCAAGGTGGT CTTTCATCCTTGACAGGCTGGTAATGTGCTGGCCACCTCCAGCTCCTGCATCGAGTCTGT AAACCAGAGCTGGTTCTCATGGCCTTCGTCACGATACCAGGATACGGAGGGGAGCCCAGG GCCATCCATACCCACCCCAGGGTAACGGGGCTGGCCTGGCATTAGTCATTATTTAGTTTC CAGGCCAACCATCCAGATAGAGATTCCCTCTTTCCTTTGAGCAGTGCTCTCAAGAGCTCC GTGCCTGTCCACAATGACCTAGAGTGCATCCTGCTCATTGTCAGTGTAGCCCCTCGCCCC TATATTCATCCAGGATACTTGGAAGTGCTAAAATAGGAAGGGATTCGGCTTTCAACTTTG CTACCATCTTCCCTGAAGCAGGAAAATGAACATGGACTTAAATGTTCTTTGAAAAAACCA AAGTTTTAAGATTTGCTGTGTGATGAAGTGACAGGGAGGGCCGGAGTCAGCAGGTGCCAG ACTTTCTGTTCTGTCTGCCATGGGTTTGTCCAGCTCAGGTAGCTCTAGGAGCACCATCCT GCCCTAGCAGAGCCCAGGCCTTGCCCTCATGAAGCATCATTGAAATAGCAGGAGCATGTT GATTTCTTGGTTAGGTTGCATTATAATAACAAGAGTCAGAACATTAATTCGAAACAACTT GCAGTATGCATTTCTTCACACCAGTACATTCTTAAGTGTACTTGTTTATAAGGAATAACA TAAACTAATCTGTACCTTTATATATATGTGTGTGTACATATATACATATATAAACTGTAT AGTGTACATGGTAATGATTTATTGCTATGCCCCAGATCCTTAATGTAGTTCTCATCCTCC GCATGCCCTCAGCCACAAGCGGGTGACTGACTGTTCCCTGATGATTTGGCCCACCTCCTG TGTTTGGACCTCTAGGGAGGAGGGTTTTGGTCATACTCTCCTTATCCTCGTGCACAGAAA TGCTCAGGGTCCCCATGTGCCTGTTGTTCAGCCCTCTCTCTTGTTCCCTTTCTGAGCATG TGGTCCTTCCCCAGGCTGTGGGACAGCTGCCTTCCCACGAAAGTGTAAAGCAGTATTAAG ATCATTACTGCATGTGCCCTAAAAACCCAAGTTTTCTATTCCCTTAGGACAGAAAATTGC ATGTGAGGTGGGATAATCGAGTTTCAGTGACCCACGTCAGTTACACATTAAAGCCAGACC CCATGATAAAATTCCACAAAATGGAAATAAAACTCAAATTTCTTTAGCATTGTGTAAATA AATCTGAATGTGTTTAACTTTGTACTGGTAATTTTCTGTATATTTGGAATATTTGGGTTA AAAATAAAACAGACTGGACTTTGTTACCTGA |
Protein Sequence | >6272 : length: 831 MERPWGAADGLSRWPHGLGLLLLLQLLPPSTLSQDRLDAPPPPAAPLPRWSGPIGVSWGL RAAAAGGAFPRGGRWRRSAPGEDEECGRVRDFVAKLANNTHQHVFDDLRGSVSLSWVGDS TGVILVLTTFHVPLVIMTFGQSKLYRSEDYGKNFKDITDLINNTFIRTEFGMAIGPENSG KVVLTAEVSGGSRGGRIFRSSDFAKNFVQTDLPFHPLTQMMYSPQNSDYLLALSTENGLW VSKNFGGKWEEIHKAVCLAKWGSDNTIFFTTYANGSCKADLGALELWRTSDLGKSFKTIG VKIYSFGLGGRFLFASVMADKDTTRRIHVSTDQGDTWSMAQLPSVGQEQFYSILAANDDM VFMHVDEPGDTGFGTIFTSDDRGIVYSKSLDRHLYTTTGGETDFTNVTSLRGVYITSVLS EDNSIQTMITFDQGGRWTHLRKPENSECDATAKNKNECSLHIHASYSISQKLNVPMAPLS EPNAVGIVIAHGSVGDAISVMVPDVYISDDGGYSWTKMLEGPHYYTILDSGGIIVAIEHS SRPINVIKFSTDEGQCWQTYTFTRDPIYFTGLASEPGARSMNISIWGFTESFLTSQWVSY TIDFKDILERNCEEKDYTIWLAHSTDPEDYEDGCILGYKEQFLRLRKSSVCQNGRDYVVT KQPSICLCSLEDFLCDFGYYRPENDSKCVEQPELKGHDLEFCLYGREEHLTTNGYRKIPG DKCQGGVNPVREVKDLKKKCTSNFLSPEKQNSKSNSVPIILAIVGLMLVTVVAGVLIVKK YVCGGRFLVHRYSVLQQHAEANGVDGVDALDTASHTNKSGYHDDSDEDLLE |