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Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

60

Name

ACTB

Synonymous

actin, beta;ACTB;actin, beta

Definition

PS1TP5-binding protein 1|actin, cytoplasmic 1|beta cytoskeletal actin

Position

7p22

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

beta-actin(h) + Smad3(m.s.) <==> beta-actin(h):Smad3(m.s.) (binding)
beta-actin(h) + Pontin52(h) + Reptin52(h) + BAF53a(h) + c-Myc(m.s.) <==> beta-actin(h):Pontin52(h):Reptin52(h):BAF53a(h):c-Myc(m.s.) (binding)
beta-actin(h) + MGMT(h) <==> beta-actin(h):MGMT(h) (binding)
p47phox(m.s.) + beta-actin(h) <==> p47phox(m.s.):beta-actin(h) (binding)
Rac1(m.s.) + beta-actin(h) <==> Rac1(m.s.):beta-actin(h) (binding)
Rac2(m.s.) + beta-actin(h) <==> Rac2(m.s.):beta-actin(h) (binding)
p47phox(h) + beta-actin(h) <==> p47phox(h):beta-actin(h) (binding)
Rac(h) + beta-actin(h) <==> Rac(h):beta-actin(h) (binding)
PKCepsilon(h) + beta-actin(h) <==> PKCepsilon(h):beta-actin(h) (binding)
beta-actin(h) + AR-isoform1(h) <==> beta-actin(h):AR-isoform1(h) (binding)
2 beta-actin(h) <==> (beta-actin(h))2 (binding)
beta-actin(h) + gamma-actin(h) <==> beta-actin(h):gamma-actin(h) (binding)
beta-actin(h) + cofilin-1(h) <==> beta-actin(h):cofilin-1(h) (binding)
beta-actin(h) + cofilin-2(h) <==> beta-actin(h):cofilin-2(h) (binding)
beta-actin(h) + ADF(h) <==> beta-actin(h):ADF(h) (binding)
bbs4(h) + beta-actin(h) <==> bbs4(h):beta-actin(h) (binding)
ACTB(h) --> beta-actin(h) (expression).
ACTB(h) --> beta-actin(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

1N-acetylmethionine (By similarity).Swiss-Prot 53.0
2N-acetylaspartate.Swiss-Prot 53.0
73Tele-methylhistidine (By similarity).Swiss-Prot 53.0
166Phosphotyrosine.Swiss-Prot 53.0
218Phosphotyrosine.Swiss-Prot 53.0
294Phosphotyrosine.Swiss-Prot 53.0
218Phosphotyrosine15592455Phospho.ELM 6.0
294Phosphotyrosine15592455Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr7

Promoter: 5536247 - 5538247Agilent_014791

chr7

Promoter: 5536247 - 5538247GSE27584