| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 5880 |
Name | RAC2 |
Synonymous | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2);RAC2;ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
Definition | Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP-binding protein Rac2)|ras-related C3 botulinum toxin substrate 2|small G protein |
Position | 22q13.1 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | Rac2(h) + RhoGDI-1(h) <==> Rac2(h):RhoGDI-1(h) (binding) | Rac2(h) --Caspase-3(h)--> protein remnants (cleavage) | Rac2(h) --Caspase-8(h)--> protein remnants (cleavage) | Rac2(h) + RhoGDI(h) <==> Rac2(h):RhoGDI(h) (binding) | RAC2(h) --> Rac2(h) (expression). | Rac2(h) + p65PAK(h) <==> Rac2(h):p65PAK(h) (binding) | Rac2(h) --> p65PAK(h){p} (increase of phosphorylation) | RAC2(h) --> Rac2(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 39 | ADP-ribosylasparagine (by botulinumtoxin) (By similarity). | Swiss-Prot 53.0 | 189 | Cysteine methyl ester (Probable). | Swiss-Prot 53.0 | 189 | S-geranylgeranyl cysteine. | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr22 |
Promoter: 35969751 - 35971751 | GSE27584 |
chr22 |
Promoter: 35969751 - 35971751 | Agilent_014791 |