| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 5880 |
Name | RAC2 |
Synonym | EN-7|Gx|HSPC022|p21-Rac2;ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2);RAC2;ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
Definition | Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP-binding protein Rac2)|ras-related C3 botulinum toxin substrate 2|small G protein |
Position | 22q13.1 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Fc gamma R-mediated phagocytosis;KEGG PATHWAY;hsa04666 |
Pathway | Axon guidance mediated by netrin;PANTHER;P00009 |
Pathway | B cell receptor signaling pathway;KEGG PATHWAY;hsa04662 |
Pathway | Axon guidance mediated by Slit/Robo;PANTHER;P00008 |
Pathway | Signaling by GPCR;Reactome;REACT:14797 |
Pathway | Regulation of actin cytoskeleton;KEGG PATHWAY;hsa04810 |
Pathway | MAPK signaling pathway;KEGG PATHWAY;hsa04010 |
Pathway | FGF signaling pathway;PANTHER;P00021 |
Pathway | Pancreatic cancer;KEGG PATHWAY;hsa05212 |
Pathway | Wnt signaling pathway;KEGG PATHWAY;hsa04310 |
Pathway | Focal adhesion;KEGG PATHWAY;hsa04510 |
Pathway | Signaling by Rho GTPases;Reactome;REACT:11044 |
Pathway | T cell activation;PANTHER;P00053 |
Pathway | Axon guidance;KEGG PATHWAY;hsa04360 |
Pathway | EGF receptor signaling pathway;PANTHER;P00018 |
Pathway | Leukocyte transendothelial migration;KEGG PATHWAY;hsa04670 |
Pathway | Axon guidance;Reactome;REACT:18266 |
Pathway | Inflammation mediated by chemokine and cytokine signaling pathway;PANTHER;P00031 |
Pathway | Colorectal cancer;KEGG PATHWAY;hsa05210 |
Pathway | Adherens junction;KEGG PATHWAY;hsa04520 |
Pathway | VEGF signaling pathway;KEGG PATHWAY;hsa04370 |
Pathway | B cell activation;PANTHER;P00010 |
Pathway | Integrin signalling pathway;PANTHER;P00034 |
Pathway | Huntington disease;PANTHER;P00029 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | Ras Pathway;PANTHER;P04393 |
Pathway | Axon guidance mediated by semaphorins;PANTHER;P00007 |
Pathway | Fc epsilon RI signaling pathway;KEGG PATHWAY;hsa04664 |
Pathway | Viral myocarditis;KEGG PATHWAY;hsa05416 |
Pathway | Hemostasis;Reactome;REACT:604 |
Pathway | Chemokine signaling pathway;KEGG PATHWAY;hsa04062 |
Pathway | Natural killer cell mediated cytotoxicity;KEGG PATHWAY;hsa04650 |
Pathway | Cytoskeletal regulation by Rho GTPase;PANTHER;P00016 |
Disease | Primary immunodeficiency;KEGG DISEASE |
Disease | IMMUNE;GAD |
Disease | Immune system diseases;KEGG DISEASE |
Disease | neutrophil immunodeficiency syndrome;GAD |
Disease | Brain tumor;FunDO |
Disease | Neutrophil immunodeficiency syndrome;OMIM |
Disease | Leukocyte adhesion deficiency;KEGG DISEASE;H00099 |
External Links | |
Links to Entrez Gene | 5880 |
Links to all GeneRIF Items | 5880 |
Links to iHOP | 5880 |
Sequence Information | |
Nucleotide Sequence | >5880 : length: 1538 AGCAGCTTGAGTAAGTTCCCCTTCCGTTTCCTCCTGCCCCACCACCGCTGCTCCTCAGCA GGCGCCTCACCAGCCTCCACACCCCTTGCGCCCGCAGAAACGCGCCTGGCCCTGAGCTGT CACCACCGACACTCTCCAGGCTCCGGACACGATGCAGGCCATCAAGTGTGTGGTGGTGGG AGATGGGGCCGTGGGCAAGACCTGCCTTCTCATCAGCTACACCACCAACGCCTTTCCCGG AGAGTACATCCCCACCGTGTTTGACAACTATTCAGCCAATGTGATGGTGGACAGCAAGCC AGTGAACCTGGGGCTGTGGGACACTGCTGGGCAGGAGGACTACGACCGTCTCCGGCCGCT CTCCTATCCACAGACGGACGTCTTCCTCATCTGCTTCTCCCTCGTCAGCCCAGCCTCTTA TGAGAACGTCCGCGCCAAGTGGTTCCCAGAAGTGCGGCACCACTGCCCCAGCACACCCAT CATCCTGGTGGGCACCAAGCTGGACCTGCGGGACGACAAGGACACCATCGAGAAACTGAA GGAGAAGAAGCTGGCTCCCATCACCTACCCGCAGGGCCTGGCACTGGCCAAGGAGATTGA CTCGGTGAAATACCTGGAGTGCTCAGCTCTCACCCAGAGAGGCCTGAAAACCGTGTTCGA CGAGGCCATCCGGGCCGTGCTGTGCCCTCAGCCCACGCGGCAGCAGAAGCGCGCCTGCAG CCTCCTCTAGGGGTTGCACCCCAGCGCTCCCACCTAGATGGGTCTGATCCTCCAGGATCC CCACCCAAAGCCTGATGGCACCCCGGCTGGCCATGCTGTCCCCTCCCTGTGGCGTTTCTT AGCAGATGGCTGCAGAGCTTCGTTGATGGTCTTTTCTGTACTGGAGGCCTCCTGAGGCCA GGAACGTGCAAATTTGCAGGTGCTGCATCCCAAGCCCCTCATGCTCCTGCCTTCCTGAGG GCCAGAGGGGAGCCCCAGGACCCATTAAGCCACCCCCGTGTTCCTGCCGTCAGTGCCAAC TGCCGCATGTGGAAGCATCTACCCGTTCACTCCAGTCCCACCCCACGCCTGACTCCCCTC TGGAAACTGCAGGCCAGATGGTTGCTGCCACAACTTGTGTACCTTCAGGGATGGGGCTCT TACTCCCTCCTGAGGCCAGCTGCTCTAATATCGATGGTCCTGCTTGCCAGAGAGTTCCTC TACCCAGCAAAAATGAGTGTCTCAGAAGTGTGCTCCTCTGGCCTCAGTTCTCCTCTTTTG GAACAACATAAAACAAATTTAATTTTCTACGCCTCTGGGGATATCTGCTCAGCCAATGGA AAATCTGGGTTCAACCAGCCCCTGCCATTTCTTAAGACTTTCTGCTGCACTCACAGGATC CTGAGCTGCACTTACCTGTGAGAGTCTTCAAACTTTTAAACCTTGCCAGTCAGGACTTTT GCTATTGCAAATAGAAAACCCAACTCAACCTGCTTAAGCAGAAAATAAATTTATTGATTC AAGTTTGGAGAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
Protein Sequence | >5880 : length: 192 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAG QEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLR DDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQ PTRQQKRACSLL |