| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 56924 |
Name | PAK6 |
Synonymous | p21 protein (Cdc42/Rac)-activated kinase 6;PAK6;p21 protein (Cdc42/Rac)-activated kinase 6 |
Definition | p21(CDKN1A)-activated kinase 6|serine/threonine-protein kinase PAK 6 |
Position | 15q14 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | AR-isoform1(h) + PAK6(h) <==> AR-isoform1(h):PAK6(h) (binding) | AR(h) + PAK6(h) <==> AR(h):PAK6(h) (binding) | ER-alpha-L(h) + PAK6(h) <==> ER-alpha-L(h):PAK6(h) (binding) | PAK6(h) --> PAK6(h) (expression). | AR-isoform1(h) + PAK6(h) <==> AR-isoform1(h):PAK6(h) (binding) | 14-3-3tau(h) + PAK6(h) <==> 14-3-3tau(h):PAK6(h) (binding) | PAK6(h) --> PAK6(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 560 | Phosphoserine. | Swiss-Prot 53.0 | 165 | Phosphoserine (MAPK14) | 15550393 | Phospho.ELM 6.0 | 560 | Phosphoserine | 14573606;15550393 | Phospho.ELM 6.0 | 564 | Phosphothreonine (MAP2K6) | 15550393 | Phospho.ELM 6.0 | 566 | Phosphotyrosine (MAP2K6) | 15550393 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr15 |
Promoter: 38317868 - 38319868 | Agilent_014791 |
chr15 |
Promoter: 38317868 - 38319868 | GSE27584 |
chr15 |
Promoter: 38317868 - 38319868 | Agilent_014791_44K |