Entrez Gene

Basic Information
Gene ID	5621
Name	PRNP
Synonymous	prion protein;PRNP;prion protein
Definition	CD230 antigen\|major prion protein\|prion-related protein
Position	20p13
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
LRP(h) + PrPc(h) <==> LRP(h):PrPc(h) (binding)
PRNP(h) --> PrPc(h) (expression).
PrPc(h) + heparin <==> PrPc(h):heparin (binding)
PrPc(h) + LPS <==> PrPc(h):LPS (binding)
PRNP(h) --> PrPc(h) (expression).
TGFalpha(h) --> PrPc(h) (increase of abundance)

Location (AA)	PTM type	Database
Post Translational Modification [Top]
181	N-linked (GlcNAc...).	Swiss-Prot 53.0
197	N-linked (GlcNAc...).	Swiss-Prot 53.0
230	GPI-anchor amidated serine (Bysimilarity).	Swiss-Prot 53.0

Transcription Factors [Top]