| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 5621 |
Name | PRNP |
Synonym | ASCR|AltPrP|CD230|CJD|GSS|KURU|PRIP|PrP|PrP27-30|PrP33-35C|PrPc|p27-30;prion protein;PRNP;prion protein |
Definition | CD230 antigen|major prion protein|prion-related protein |
Position | 20p13 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | prion pathway;PID BioCarta;100062 |
Pathway | Glypican 1 network;PID Curated;200021 |
Pathway | Axon guidance;Reactome;REACT:18266 |
Pathway | Prion diseases;KEGG PATHWAY;hsa05020 |
Pathway | NCAM1 interactions;PID Reactome;500087 |
Disease | Alzheimer's disease;GAD |
Disease | Gerstmann-Straussler disease;OMIM |
Disease | Prion diseases;KEGG DISEASE;H00061 |
Disease | Nervous system diseases;KEGG DISEASE |
Disease | Creutzfeldt-Jakob disease;NHGRI |
Disease | AGING;GAD |
Disease | encephalopathies, transmissible spongiform;GAD |
Disease | Early cognitive decline;GAD |
Disease | cerebral aging;GAD |
Disease | Wilson disease;GAD |
Disease | Sporadic Creutzfeldt-Jakob disease;GAD |
Disease | Huntington disease-like 1;OMIM |
Disease | METABOLIC;GAD |
Disease | Epilepsy, Temporal Lobe;GAD |
Disease | diverse clinicopathologic phenotypes;GAD |
Disease | PSYCH;GAD |
Disease | Platelet aggregation;NHGRI |
Disease | Prion disease with protracted course;OMIM |
Disease | Insomnia, fatal familial;OMIM |
Disease | human long-term memory;GAD |
Disease | CANCER;GAD |
Disease | Inherited Creutzfeldt-Jakob disease;GAD |
Disease | NEUROLOGICAL;GAD |
Disease | Jakob-Creutzfeldt disease;GAD |
Disease | schizophrenia;GAD |
Disease | Neurodegenerative diseases;KEGG DISEASE |
Disease | Creutzfeldt-Jakob disease;OMIM |
Disease | Creutzfeldt-Jakob disease;GAD |
External Links | |
Links to Entrez Gene | 5621 |
Links to all GeneRIF Items | 5621 |
Links to iHOP | 5621 |
Sequence Information | |
Nucleotide Sequence | >5621 : length: 2755 ATTAAAGATGATTTTTACAGTCAATGAGCCACGTCAGGGAGCGATGGCACCCGCAGGCGG TATCAACTGATGCAAGTGTTCAAGCGAATCTCAACTCGTTTTTTCCGGTGACTCATTCCC GGCCCTGCTTGGCAGCGCTGCACCCTTTAACTTAAACCTCGGCCGGCCGCCCGCCGGGGG CACAGAGTGTGCGCCGGGCCGCGCGGCAATTGGTCCCCGCGCCGACCTCCGCCCGCGAGC GCCGCCGCTTCCCTTCCCCGCCCCGCGTCCCTCCCCCTCGGCCCCGCGCGTCGCCTGTCC TCCGAGCCAGTCGCTGACAGCCGCGGCGCCGCGAGCTTCTCCTCTCCTCACGACCGAGGC AGAGCAGTCATTATGGCGAACCTTGGCTGCTGGATGCTGGTTCTCTTTGTGGCCACATGG AGTGACCTGGGCCTCTGCAAGAAGCGCCCGAAGCCTGGAGGATGGAACACTGGGGGCAGC CGATACCCGGGGCAGGGCAGCCCTGGAGGCAACCGCTACCCACCTCAGGGCGGTGGTGGC TGGGGGCAGCCTCATGGTGGTGGCTGGGGGCAGCCTCATGGTGGTGGCTGGGGGCAGCCC CATGGTGGTGGCTGGGGACAGCCTCATGGTGGTGGCTGGGGTCAAGGAGGTGGCACCCAC AGTCAGTGGAACAAGCCGAGTAAGCCAAAAACCAACATGAAGCACATGGCTGGTGCTGCA GCAGCTGGGGCAGTGGTGGGGGGCCTTGGCGGCTACATGCTGGGAAGTGCCATGAGCAGG CCCATCATACATTTCGGCAGTGACTATGAGGACCGTTACTATCGTGAAAACATGCACCGT TACCCCAACCAAGTGTACTACAGGCCCATGGATGAGTACAGCAACCAGAACAACTTTGTG CACGACTGCGTCAATATCACAATCAAGCAGCACACGGTCACCACAACCACCAAGGGGGAG AACTTCACCGAGACCGACGTTAAGATGATGGAGCGCGTGGTTGAGCAGATGTGTATCACC CAGTACGAGAGGGAATCTCAGGCCTATTACCAGAGAGGATCGAGCATGGTCCTCTTCTCC TCTCCACCTGTGATCCTCCTGATCTCTTTCCTCATCTTCCTGATAGTGGGATGAGGAAGG TCTTCCTGTTTTCACCATCTTTCTAATCTTTTTCCAGCTTGAGGGAGGCGGTATCCACCT GCAGCCCTTTTAGTGGTGGTGTCTCACTCTTTCTTCTCTCTTTGTCCCGGATAGGCTAAT CAATACCCTTGGCACTGATGGGCACTGGAAAACATAGAGTAGACCTGAGATGCTGGTCAA GCCCCCTTTGATTGAGTTCATCATGAGCCGTTGCTAATGCCAGGCCAGTAAAAGTATAAC AGCAAATAACCATTGGTTAATCTGGACTTATTTTTGGACTTAGTGCAACAGGTTGAGGCT AAAACAAATCTCAGAACAGTCTGAAATACCTTTGCCTGGATACCTCTGGCTCCTTCAGCA GCTAGAGCTCAGTATACTAATGCCCTATCTTAGTAGAGATTTCATAGCTATTTAGAGATA TTTTCCATTTTAAGAAAACCCGACAACATTTCTGCCAGGTTTGTTAGGAGGCCACATGAT ACTTATTCAAAAAAATCCTAGAGATTCTTAGCTCTTGGGATGCAGGCTCAGCCCGCTGGA GCATGAGCTCTGTGTGTACCGAGAACTGGGGTGATGTTTTACTTTTCACAGTATGGGCTA CACAGCAGCTGTTCAACAAGAGTAAATATTGTCACAACACTGAACCTCTGGCTAGAGGAC ATATTCACAGTGAACATAACTGTAACATATATGAAAGGCTTCTGGGACTTGAAATCAAAT GTTTGGGAATGGTGCCCTTGGAGGCAACCTCCCATTTTAGATGTTTAAAGGACCCTATAT GTGGCATTCCTTTCTTTAAACTATAGGTAATTAAGGCAGCTGAAAAGTAAATTGCCTTCT AGACACTGAAGGCAAATCTCCTTTGTCCATTTACCTGGAAACCAGAATGATTTTGACATA CAGGAGAGCTGCAGTTGTGAAAGCACCATCATCATAGAGGATGATGTAATTAAAAAATGG TCAGTGTGCAAAGAAAAGAACTGCTTGCATTTCTTTATTTCTGTCTCATAATTGTCAAAA ACCAGAATTAGGTCAAGTTCATAGTTTCTGTAATTGGCTTTTGAATCAAAGAATAGGGAG ACAATCTAAAAAATATCTTAGGTTGGAGATGACAGAAATATGATTGATTTGAAGTGGAAA AAGAAATTCTGTTAATGTTAATTAAAGTAAAATTATTCCCTGAATTGTTTGATATTGTCA CCTAGCAGATATGTATTACTTTTCTGCAATGTTATTATTGGCTTGCACTTTGTGAGTATT CTATGTAAAAATATATATGTATATAAAATATATATTGCATAGGACAGACTTAGGAGTTTT GTTTAGAGCAGTTAACATCTGAAGTGTCTAATGCATTAACTTTTGTAAGGTACTGAATAC TTAATATGTGGGAAACCCTTTTGCGTGGTCCTTAGGCTTACAATGTGCACTGAATCGTTT CATGTAAGAATCCAAAGTGGACACCATTAACAGGTCTTTGAAATATGCATGTACTTTATA TTTTCTATATTTGTAACTTTGCATGTTCTTGTTTTGTTATATAAAAAAATTGTAAATGTT TAATATCTGACTGAAATTAAACGAGCGAAGATGAGCACCAAAAAAAAAAAAAAAA |
Protein Sequence | >5621 : length: 253 MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQP HGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGA VVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCV NITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPV ILLISFLIFLIVG |