Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

5327

Name

PLAT

Synonymous

plasminogen activator, tissue;PLAT;plasminogen activator, tissue

Definition

alteplase|plasminogen activator, tissue type|reteplase|t-plasminogen activator|tissue plasminogen activator (t-PA)|tissue-type plasminogen activator

Position

8p12

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

tPA(h) --> tPA-isoform1(h) (expression).
tPA(h) --> tPA-isoform2(h) (expression).
tPA(h) --> tPA(h) (expression).
NR1-A(r) --tPA(h)--> NR1-A-p28(r) + protein remnants (cleavage)
NR1(m) --tPA(h)--> protein remnants (cleavage)

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

152N-linked (GlcNAc...).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr8

Promoter: 42183851 - 42185851GoldenGate_Methylation_Cancer_Panel_I

chr8

Promoter: 42183851 - 42185851GoldenGate_Methylation_Cancer_Panel_I

chr8

Promoter: 42183851 - 42185851GoldenGate_Methylation_Cancer_Panel_I

chr8

Promoter: 42183851 - 42185851GSE27584

chr8

Promoter: 42183851 - 42185851GSE27584