| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 4314 |
Name | MMP3 |
Synonymous | matrix metallopeptidase 3;MMP3;matrix metallopeptidase 3 |
Definition | matrix metallopeptidase 3 (stromelysin 1, progelatinase)|matrix metalloproteinase 3 (stromelysin 1, progelatinase)|matrix metalloproteinase-3|proteoglycanase|stromelysin-1|transin-1 |
Position | 11q22.3 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | stromelysin1(h) --> CTGF(h) (DNA binding). | IL-17A(h) --> stromelysin1(h) (activation) | MMP3(h) --> stromelysin1(h) (expression). | IL-17A(h) --> stromelysin1(h) (increase of abundance) | Jak3(h) --> stromelysin1(h) (increase of abundance) | ErbB1(h) --> stromelysin1(h) (increase of abundance) | HB-EGF(h) --stromelysin1(h)--> HB-EGF-ECD(h) + protein remnants (processing; cleavage) | stromelysin1(h) --> CTGF(h) (DNA binding; transactivation). | MMP3(h) --> stromelysin1(h) (expression). | BDNF(r) --stromelysin1(h)--> BDNF-p14(r) + protein remnants (cleavage) |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 120 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
There is no record for MMP3 | ||