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Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

4168

Name

MCF2

Synonymous

MCF.2 cell line derived transforming sequence;MCF2;MCF.2 cell line derived transforming sequence

Definition

Oncogene MCF2 (oncogene DBL)|proto-oncogene DBL|proto-oncogene MCF-2

Position

Xq27

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

Dbl(h) + Cdc42(m.s.) <==> Dbl(h):Cdc42(m.s.) (binding)
Rac1(m.s.) + Dbl(h) <==> Rac1(m.s.):Dbl(h) (binding)
RhoA(m.s.) + Dbl(h) <==> RhoA(m.s.):Dbl(h) (binding)
RhoG(m.s.) + Dbl(h) <==> RhoG(m.s.):Dbl(h) (binding)
MCF2(h) --> Dbl(h) (expression).
RhoA(v.s.):GDP + GTP --Dbl(h)--> RhoA(v.s.):GTP + GDP (exchange)
Cdc42(v.s.):GDP + GTP --Dbl(h)--> Cdc42(v.s.):GTP + GDP (exchange)
rhoB(v.s.):GDP + GTP --Dbl(h)--> rhoB(v.s.):GTP + GDP (exchange)
RhoG(v.s.):GDP + GTP --Dbl(h)--> RhoG(v.s.):GTP + GDP (exchange)
Cdc42(h):GDP + GTP --Dbl(h)--> Cdc42(h):GTP + GDP (exchange)
RhoA(h):GDP + GTP --Dbl(h)--> RhoA(h):GTP + GDP (exchange)
Rac1(m.s.):GDP + GTP --Dbl(h)--> Rac1(m.s.):GTP + GDP (exchange)
RhoA(m.s.):GDP + GTP --Dbl(h)--> RhoA(m.s.):GTP + GDP (exchange)
RhoG(m.s.):GDP + GTP --Dbl(h)--> RhoG(m.s.):GTP + GDP (exchange)
Cdc42(m.s.):GDP + GTP --Dbl(h)--> Cdc42(m.s.):GTP + GDP (exchange)
MCF2(h) --> Dbl-xbb5(h) (expression).
MCF2(h) --> Dbl-Var.1(h) (expression).
MCF2(h) --> Dbl-Var.2(h) (expression).
MCF2(h) --> Dbl-Var.3(h) (expression).
MCF2(h) --> Dbl-Var.4(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

742Phosphoserine.Swiss-Prot 53.0

Methylation Profile   [Top]

There is no record for MCF2