| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 4168 |
Name | MCF2 |
Synonym | ARHGEF21|DBL;MCF.2 cell line derived transforming sequence;MCF2;MCF.2 cell line derived transforming sequence |
Definition | Oncogene MCF2 (oncogene DBL)|proto-oncogene DBL|proto-oncogene MCF-2 |
Position | Xq27 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Regulation of CDC42 activity;PID Curated;200059 |
Pathway | Signaling by Rho GTPases;Reactome;REACT:11044 |
Pathway | Signaling by GPCR;Reactome;REACT:14797 |
Pathway | Regulation of RhoA activity;PID Curated;200050 |
Pathway | Regulation of RAC1 activity;PID Curated;200165 |
Pathway | Signalling by NGF;Reactome;REACT:11061 |
External Links | |
Links to Entrez Gene | 4168 |
Links to all GeneRIF Items | 4168 |
Links to iHOP | 4168 |
Sequence Information | |
Nucleotide Sequence | >4168 : length: 4031 TCAGATTGGCTTTGAAACTTTTTTTCATGTTAAGAGCAAGAAGGCTTTTGTTCTTGGAGC AGGCAGAGAGTATTGTACATTCTTTTGGCCGAGGAAACAGAATGAGCTGCGACAGTCTTA AGGACAAACATTTGTGGTAACCCACATTTTGAGGGCCCACTATATGCCAAGCCCTGGAAG ACAGTGCTTAATAAGACATTTCTTCTGGCATCAAGGGCCTCAGAATATTTCTGAGTGATA GACCTGCAAACAATTGCAACACATGATAAGAATCAGCTTGAGAAAGAAACCGATCTGCTC CTCCGTATAAAGGACATCAGTCATTTCTTAATGCAAGACATCGCCTTCTTGTCTGGTGGC CGGGGAAAGGACAATGCTTGGATCATTACGTTTCCAGAAAACTGTAATTTTAGATGTATA CCAGAGGAAGTAATAGCAAAAGTACTTACTTACCTGACATCTATTGCAAGGCAAAATGGA TCAGACTCCCGGTTTACCATTATTCTGGATCGAAGATTGGATACATGGTCTTCTCTCAAA ATCTCTCTCCAAAAAATCTCGGCTTCCTTCCCTGGGAACTTGCACTTGGTTTTGGTTTTA CGTCCTACCAGCTTTCTTCAACGAACGTTCACAGACATTGGATTTTGGTTTAGTCAGGAG GATTTTATGCTTAAATTACCAGTTGTTATGCTGAGCTCAGTTAGTGATTTGCTGACATAC ATTGATGACAAGCAATTAACCCCTGAGTTAGGCGGCACCTTGCAGTACTGCCACAGTGAA TGGATCATCTTCAGAAATGCTATAGAAAATTTTGCCCTCACAGTGAAAGAAATGGCTCAG ATGTTACAGTCCTTTGGAACTGAACTGGCTGAGACAGAACTACCAGATGATATTCCCTCA ATAGAAGAAATTCTGGCAATTCGTGCTGAAAGGTATCATCTGTTGAAGAATGATATTACA GCTGTAACCAAAGAAGGAAAAATTCTGCTAACAAATCTGGAAGTGCCTGACACTGAAGGA GCTGTCAGTTCAAGACTAGAATGTCATCGGCAAATAAGTGGTGACTGGCAAACTATTAAT AAGTTGCTGACTCAAGTACATGATATGGAAACAGCTTTTGATGGATTTTGGGAAAAACAT CAATTAAAAATGGAGCAGTATCTGCAACTATGGAAGTTTGAGCAGGATTTTCAACAGCTT GTGACTGAAGTTGAATTTCTATTAAACCAACAAGCAGAACTGGCTGATGTAACAGGGACT ATAGCTCAAGTAAAACAAAAAATAAAAAAATTGGAAAACTTAGATGAAAATTCTCAGGAG CTATTATCAAAGGCCCAGTTTGTGATATTACATGGACACAAGCTTGCAGCAAATCACCAT TATGCACTTGATTTAATCTGCCAGAGGTGCAATGAGCTACGTTACCTTTCTGATATTTTG GTTAATGAGATAAAAGCAAAACGGATACAACTCAGCAGGACCTTCAAAATGCATAAACTC CTACAGCAGGCTCGTCAATGCTGTGATGAAGGGGAATGTCTTCTAGCTAATCAGGAAATA GATAAGTTTCAGTCTAAAGAAGATGCTCAGAAAGCTCTCCAAGACATTGAAAATTTTCTT GAAATGGCTCTACCCTTTATAAATTATGAACCTGAAACACTGCAGTATGAATTTGATGTA ATATTATCTCCTGAGCTTAAGGTTCAAATGAAGACTATACAACTCAAGCTTGAAAACATT CGAAGTATATTTGAGAACCAGCAGGCTGGTTTCAGGAACCTGGCAGATAAGCATGTGAGG CCAATCCAATTTGTGGTACCCACACCTGAAAATTTGGTCACATCTGGGACACCATTTTTT TCATCTAAACAAGTGGGAGTTGGATACTCTTTCTTTCAAGCATGTAAACTTTTTTCAAAA GGGAAGAAGACTTGGAGACAAAATCAGAGCAACTTAAAAATTGAAGTGGTGCCTGATTGT CAGGAGAAGAGAAGTTCTGGTCCATCCTCCAGTTTGGACAATGGCAATAGCTTGGATGTT TTAAAGAACCACGTACTAAATGAACTGATACAGACTGAGAGAGTTTATGTTCGAGAACTG TATACTGTTTTGTTGGGTTATAGAGCGGAGATGGATAATCCAGAGATGTTTGATCTTATG CCACCTCTCCTGAGAAATAAAAAGGACATTCTCTTTGGAAACATGGCAGAAATATATGAA TTCCATAACGACATTTTCTTGAGCAGCCTGGAAAATTGTGCTCATGCTCCAGAAAGAGTG GGACCTTGTTTCCTGGAAAGGAAGGATGATTTTCAGATGTATGCAAAATATTGTCAGAAT AAGCCCAGATCAGAAACAATTTGGAGGAAGTATTCAGAATGCGCATTTTTCCAGGAATGT CAAAGAAAGTTAAAACACAGACTTAGACTGGATTCCTATTTACTCAAACCAGTGCAACGA ATCACTAAATATCAGTTATTGTTGAAGGAGCTATTAAAATATAGCAAAGACTGTGAAGGA TCTGCTCTGTTGAAGAAGGCACTCGATGCAATGCTGGATTTACTGAAGTCAGTTAATGAT TCTATGCATCAGATTGCAATAAATGGCTATATTGGAAACTTAAATGAACTGGGCAAGATG ATAATGCAAGGTGGATTCAGCGTTTGGATAGGGCACAAGAAAGGTGCTACAAAAATGAAG GATTTGGCTAGATTCAAACCAATGCAGCGACACCTTTTCTTGTATGAAAAAGCCATTGTT TTTTGCAAAAGGCGTGTTGAAAGTGGAGAAGGCTCTGACAGATACCCGTCATACAGTTTT AAACACTGTTGGAAAATGGATGAAGTTGGAATCACTGAATATGTAAAAGGTGATAACCGC AAGTTTGAAATCTGGTATGGTGAAAAGGAAGAAGTTTATATTGTCCAGGCTTCTAATGTA GATGTGAAGATGACGTGGCTAAAAGAAATAAGAAATATTTTGTTGAAGCAGCAGGAACTT TTGACAGTTAAAAAAAGAAAGCAACAGGATCAATTAACAGAACGGGATAAGTTTCAGATT TCTCTTCAGCAGAATGATGAAAAGCAACAGGGAGCTTTTATAAGTACTGAGGAAACTGAA TTGGAACACACCAGCACTGTGGTGGAGGTCTGTGAGGCAATTGCGTCAGTTCAGGCAGAA GCAAATACAGTTTGGACTGAGGCATCACAATCTGCAGAAATCTCTGAAGAACCTGCGGAA TGGTCAAGCAACTATTTCTACCCTACTTATGATGAAAATGAAGAAGAAAATAGGCCCCTC ATGAGACCTGTGTCGGAGATGGCTCTCCTATATTGATGAAGCTACTATGTCAAATGGCAA GTAGCTCTTTCCTGCCTGCTTCTCAGCTCATTTGGAAAAATACTGCGCAAAAGACATTGA GCTCAAATGATGCAGATGTTGTTTTCAGGTTAATGGACACGCAAAGAAACCACAGCACAT ACTTCTTTTCTTTCATTTAATAAAGCTTTTAATTATGGTACGCTGTCTTTTTAAAATCAT GTATTTAATGTGTCAGATATTGTGCTTGAAAGATTCTCATCTCAGAATACTTTTGGACTT GAAAATTATTTCTTCTCTACTTTGTAACCAAATGCAATCGGTGTGCCTTGGATTATTTAG TTTATTAATGAATTAAGTCAAAATTACGGCTGCAAAATGGCTAAGGTCAAGTAAAGCACA ACATTATGATTTAATATGCTTTTGTTGAAACCACAGCTTTTGTGCCCATTGTTTTAACTT GTGTGAAACAATACAAAGCCCAGAAATTCTTTTCGGGGCATGAGTAAATTTTGTTCAGGG CTACTGTCTGTATGTGCCCAGATAAAATTTTCATGAGAGTAGTTTACAAAAGCCGTATTT AAAAGTTAATATTTTCACACTTTTTTTCTGGATTTCTGCTTATAATTAATGTAACTTAAA TTAGTTGTGCTCTGCTATTTTCTGTATATTTCATGTTGTAATTCTTTTTTTCAAATAAAA ATTAATTCTTC |
Protein Sequence | >4168 : length: 1044 MAMALQRVRIAEKYGKNYLCLLQAVFVAETDLLLRIKDISHFLMQDIAFLSGGRGKDNAW IITFPENCNFRCIPEEVIAKVLTYLTSIARQNGSDSRFTIILDRRLDTWSSLKISLQKIS ASFPGNLHLVLVLRPTSFLQRTFTDIGFWFSQEDFMLKLPVVMLSSVSDLLTYIDDKQLT PELGGTLQYCHSEWIIFRNAIENFALTVKEMAQMLQSFGTELAETELPDDIPSIEEILAI RAERYHLLKNDITAVTKEGKILLTNLEVPDTEGAVSSRLECHRQISGDWQTINKLLTQVH DMETAFDGFWEKHQLKMEQYLQLWKFEQDFQQLVTEVEFLLNQQAELADVTGTIAQVKQK IKKLENLDENSQELLSKAQFVILHGHKLAANHHYALDLICQRCNELRYLSDILVNEIKAK RIQLSRTFKMHKLLQQARQCCDEGECLLANQEIDKFQSKEDAQKALQDIENFLEMALPFI NYEPETLQYEFDVILSPELKVQMKTIQLKLENIRSIFENQQAGFRNLADKHVRPIQFVVP TPENLVTSGTPFFSSKQVGVGYSFFQACKLFSKGKKTWRQNQSNLKIEVVPDCQEKRSSG PSSSLDNGNSLDVLKNHVLNELIQTERVYVRELYTVLLGYRAEMDNPEMFDLMPPLLRNK KDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFLERKDDFQMYAKYCQNKPRSETI WRKYSECAFFQECQRKLKHRLRLDSYLLKPVQRITKYQLLLKELLKYSKDCEGSALLKKA LDAMLDLLKSVNDSMHQIAINGYIGNLNELGKMIMQGGFSVWIGHKKGATKMKDLARFKP MQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHCWKMDEVGITEYVKGDNRKFEIWYG EKEEVYIVQASNVDVKMTWLKEIRNILLKQQELLTVKKRKQQDQLTERDKFQISLQQNDE KQQGAFISTEETELEHTSTVVEVCEAIASVQAEANTVWTEASQSAEISEEPAEWSSNYFY PTYDENEEENRPLMRPVSEMALLY |