| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 408 |
Name | ARRB1 |
Synonymous | arrestin, beta 1;ARRB1;arrestin, beta 1 |
Definition | arrestin 2|beta-arrestin-1 |
Position | 11q13 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | NTS1(v.s.) + beta-arrestin1(h) <==> NTS1(v.s.):beta-arrestin1(h) (binding) | ADRB2R(v.s.) + beta-arrestin1(h) <==> ADRB2R(v.s.):beta-arrestin1(h) (binding) | beta-arrestin1(h) --> cxcr4(h) (increase of abundance) | PDE4D5(h) + beta-arrestin1(h) <==> PDE4D5(h):beta-arrestin1(h) (binding) | beta-arrestin1(h) + TRAF6(m.s.) <==> beta-arrestin1(h):TRAF6(m.s.) (binding) | beta-arrestin1(h) + TRAF6(h) <==> beta-arrestin1(h):TRAF6(h) (binding) | beta-arrestin1(h) + ketohexokinase(h) <==> beta-arrestin1(h):ketohexokinase(h) (binding) | beta-arrestin1(h) + Nopp140(h) <==> beta-arrestin1(h):Nopp140(h) (binding) | beta-arrestin1(h) + HPS2(h) <==> beta-arrestin1(h):HPS2(h) (binding) | beta-arrestin1(h) + MFD1(h) <==> beta-arrestin1(h):MFD1(h) (binding) | beta-arrestin1(h) + chd1(h) <==> beta-arrestin1(h):chd1(h) (binding) | beta-arrestin1(h) + HDGF2(h) <==> beta-arrestin1(h):HDGF2(h) (binding) | beta-arrestin1(h) + BOP1(h) <==> beta-arrestin1(h):BOP1(h) (binding) | beta-arrestin1(h) + CKII-alpha(h) <==> beta-arrestin1(h):CKII-alpha(h) (binding) | beta-arrestin1(h) + arrestin-3(h) <==> beta-arrestin1(h):arrestin-3(h) (binding) | beta-arrestin2(h) + beta-arrestin1(h) <==> beta-arrestin2(h):beta-arrestin1(h) (binding) | beta-arrestin1(h) + pes1(h) <==> beta-arrestin1(h):pes1(h) (binding) | beta-arrestin1(h) + RHLP(h) <==> beta-arrestin1(h):RHLP(h) (binding) | beta-arrestin1(h) + importin-alpha3(h) <==> beta-arrestin1(h):importin-alpha3(h) (binding) | beta-arrestin1(h) + ZFP265(h) <==> beta-arrestin1(h):ZFP265(h) (binding) | beta-arrestin1(h) + RPL7L1(h) <==> beta-arrestin1(h):RPL7L1(h) (binding) | beta-arrestin1(h) + NCC2(h) <==> beta-arrestin1(h):NCC2(h) (binding) | beta-arrestin1(h) + Jak1(h) <==> beta-arrestin1(h):Jak1(h) (binding) | beta-arrestin1(h) + GTL7(h) <==> beta-arrestin1(h):GTL7(h) (binding) | beta-arrestin1(h) + CMBL(h) <==> beta-arrestin1(h):CMBL(h) (binding) | beta-arrestin1(h) + ZNF297B(h) <==> beta-arrestin1(h):ZNF297B(h) (binding) | beta-arrestin1(h) + glycine N-methyltransferase(h) <==> beta-arrestin1(h):glycine N-methyltransferase(h) (binding) | beta-arrestin1(h) --> ERK1(h){p} (increase of phosphorylation) | beta-arrestin1(h) --> ERK2(h){p} (increase of phosphorylation) | ARRB1(h) --> beta-arrestin1(h) (expression). | mdm2(m) + beta-arrestin1A(h) <==> mdm2(m):beta-arrestin1A(h) (binding) | ARRB1(h) --> beta-arrestin1A(h) (expression). | ARRB1(h) --> beta-arrestin1B(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 410 | Phosphothreonine (By similarity). | Swiss-Prot 53.0 | 412 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 412 | Phosphoserine | 10347142;9388255 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr11 |
Promoter: 74740021 - 74742021 | GSE27584 |
chr11 |
Promoter: 74740021 - 74742021 | GSE27584 |
chr11 |
Promoter: 74740021 - 74742021 | Agilent_014791_44K |