| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 408 |
Name | ARRB1 |
Synonym | ARB1|ARR1;arrestin, beta 1;ARRB1;arrestin, beta 1 |
Definition | arrestin 2|beta-arrestin-1 |
Position | 11q13 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Golgi Associated Vesicle Biogenesis;PID Reactome;500014 |
Pathway | Endocytosis;KEGG PATHWAY;hsa04144 |
Pathway | Lysosome Vesicle Biogenesis;PID Reactome;500015 |
Pathway | Hemostasis;Reactome;REACT:604 |
Pathway | visual signal transduction;PID BioCarta;100042 |
Pathway | Membrane Trafficking;Reactome;REACT:11123 |
Pathway | roles of beta arrestin dependent recruitment of src kinases in gpcr signaling;PID BioCarta;100230 |
Pathway | beta-arrestins in gpcr desensitization;PID BioCarta;100231 |
Pathway | Clathrin derived vesicle budding;PID Reactome;500013 |
Pathway | Wnt signaling pathway;PANTHER;P00057 |
Pathway | MAPK signaling pathway;KEGG PATHWAY;hsa04010 |
Pathway | Chemokine signaling pathway;KEGG PATHWAY;hsa04062 |
Pathway | attenuation of gpcr signaling;PID BioCarta;100253 |
Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway;PANTHER;P00026 |
Pathway | role of beta-arrestins in the activation and targeting of map kinases;PID BioCarta;100229 |
Pathway | Phototransduction;KEGG PATHWAY;hsa04744 |
Pathway | Inflammation mediated by chemokine and cytokine signaling pathway;PANTHER;P00031 |
Pathway | CXCR3-mediated signaling events;PID Curated;200150 |
Disease | Hypertension;FunDO |
Disease | Depression;FunDO |
Disease | CHEMDEPENDENCY;GAD |
Disease | Neoplasm metastasis;FunDO |
Disease | nicotine dependence;GAD |
External Links | |
Links to Entrez Gene | 408 |
Links to all GeneRIF Items | 408 |
Links to iHOP | 408 |
Sequence Information | |
Nucleotide Sequence | >408 : length: 7539 ACACCCCGCGCGGTTCCACGCCCCTGGCCGCGGCCCGGGCGCTGCGCTGCTCGACGCGGC GGGCGGCGGGCGGGGACCGGGGGCGGGGGCGGCGGCGGCGGCCGGGAGAGCGGAGGAGGC GGAGCAGGGAGCCGGGAGCGGGCTGGCCCGCGCTCCTCCTGCTGGCTGGGGATTTTCCAG CCTGGGCGCTGACGCCGCGGACCTCCCTGCGACCGTCGCGGACCATGGGCGACAAAGGGA CCCGAGTGTTCAAGAAGGCCAGTCCAAATGGAAAGCTCACCGTCTACCTGGGAAAGCGGG ACTTTGTGGACCACATCGACCTCGTGGACCCTGTGGATGGTGTGGTCCTGGTGGATCCTG AGTATCTCAAAGAGCGGAGAGTCTATGTGACGCTGACCTGCGCCTTCCGCTATGGCCGGG AGGACCTGGATGTCCTGGGCCTGACCTTTCGCAAGGACCTGTTTGTGGCCAACGTACAGT CGTTCCCACCGGCCCCCGAGGACAAGAAGCCCCTGACGCGGCTGCAGGAACGCCTCATCA AGAAGCTGGGCGAGCACGCTTACCCTTTCACCTTTGAGATCCCTCCAAACCTTCCATGTT CTGTGACACTGCAGCCGGGGCCCGAAGACACGGGGAAGGCTTGCGGTGTGGACTATGAAG TCAAAGCCTTCTGCGCGGAGAATTTGGAGGAGAAGATCCACAAGCGGAATTCTGTGCGTC TGGTCATCCGGAAGGTTCAGTATGCCCCAGAGAGGCCTGGCCCCCAGCCCACAGCCGAGA CCACCAGGCAGTTCCTCATGTCGGACAAGCCCTTGCACCTAGAAGCCTCTCTGGATAAGG AGATCTATTACCATGGAGAACCCATCAGCGTCAACGTCCACGTCACCAACAACACCAACA AGACGGTGAAGAAGATCAAGATCTCAGTGCGCCAGTATGCAGACATCTGCCTTTTCAACA CAGCTCAGTACAAGTGCCCTGTTGCCATGGAAGAGGCTGATGACACTGTGGCACCCAGCT CGACGTTCTGCAAGGTCTACACACTGACCCCCTTCCTAGCCAATAACCGAGAGAAGCGGG GCCTCGCCTTGGACGGGAAGCTCAAGCACGAAGACACGAACTTGGCCTCTAGCACCCTGT TGAGGGAAGGTGCCAACCGTGAGATCCTGGGGATCATTGTTTCCTACAAAGTGAAAGTGA AGCTGGTGGTGTCTCGGGGCGGCCTGTTGGGAGATCTTGCATCCAGCGACGTGGCCGTGG AACTGCCCTTCACCCTAATGCACCCCAAGCCCAAAGAGGAACCCCCGCATCGGGAAGTTC CAGAGAACGAGACGCCAGTAGATACCAATCTCATAGAACTTGACACAAATGATGACGACA TTGTATTTGAGGACTTTGCTCGCCAGAGACTGAAAGGCATGAAGGATGACAAGGAGGAAG AGGAGGATGGTACCGGCTCTCCACAGCTCAACAACAGATAGACGGGCCGGCCCTGCCTCC ACGTGGCTCCGGCTCCACTCTCGTGCACTCGGATGCTTACTCGTCTTCTTCCTGTTCTGG TTTCTTTTCCCCTTTGTTCTTCCAGTTTCTACCAGGGGGCCCCGTGGGCTTCCAGATCAC GGTGATGAACCTCTGGCCTCAGGATTGGCCCCACATCACCACGCCAACAGGACCACAGCG CACTGGCTCCACCCCATCTCTGCCATCTCCACTCCCCTCCTTTTCATGCTGTCTCCCAGA AAAGCTGCCAGGGCTCTGGCCTTGGAATTGGACTTGAGATGGGGAGCAGACAGGGGAGGA TGGGGAATGTGGGACACGGTGTGGTGGGCATGAGGGCTTGGAGGGGTGGGGATGAGGGCT CAAGACACGAGAGAAGATGTCCACGGTCCCAGGTGGTTAACAAAGTTCTGGCAGCTAAAA GATGACCGCGTTGAAGGCCACCTCCTTCTGGCTGGGAGGGGCAGAACTGTGGACAGATTC TCAATGCCTTTTTGAAGTTCTGACCCACCAAAGACCTTCTGCCTTCACCCTCCTCCCCAC CTGATGTCCCTCTGTGTCTGATAGTGATGTTGGTGAAAGTTCGTAGACCCCAGGAGTAGA GAAAAGCAACTGGACTGACTTTCTTACCAGCAGTTACCTAGACTGAGGCAAGCTGTGTGG ACTCACCCAAGTATATTTCAGTACTGTCAGGCTGTGACATCTTAGCTACCTTGTATTTCA AGTGCATGGCCCTGTCTAGAGATATGCACAGAGAGAAAAGCAGAGGGAGGGAGGGAGGGG GTCTTCAGCAAGCACCAGCCCCCAGCAGAGTGAGCTGAAGCTCCTGAGGAGGGTTCCCGA AGGGGGGCGCTCAGAGATGGGGGCAGGGGGCGGGGAGAGGAGAGTCTGCCTTATGTCCCT TCCTTGTGGACTTCACATGGTCATGCAGGAAGTGAGGATGGGTGTCCAGCGGGGGCCGAG GCCACTAGTATCCTCCTGCTTCCCCCTGCCATTCTCCAGGGCTGGACTGACCCTATGGAC TGGGAGAGAGTGCCTGAGGCCACCATGCCACAGTCAAAGGGGGTCCTATCTCAGAAGGTG GCAGCATCCACTGAGATATCCTCACCCGAAGGGAAGGAGGCTGCTGGGTAGCAAATAAGC CCCTTCTTTTCTTGGTGAGTTGATGACCTCCAATAGCTCCCAGTGTCATGGGTACCCAGT ACGCATTAGCTGGTGTTGGGTTGATTGAGACCTGGGGCAGTTCCTGGGGCAAGAAGCCAG ATGGGAGATGAGATAGAAAGTGTTAGGAGTTATCCTCTTTGCCTGGCCTTTGAGAATAAC TTACTGTGTGACTTTGGGCAAGTTCCTTCCCCACTCTGGGCCTCAGTTTCTCACTTGGGA AAGCAAGGAGTTTGACCAGATGATCACAATGGGCCTTCCTAGCTCTGGCCACCAAGAATT TGTGAACATTAGAGCTCCTGGTCTGGTGGGTAGAGCCAGAGCTGCTGACTGGTCTCTCTG CCTCCAGAGGGGATTTATTGGACCTCAGAGGTGGCAGGGCCCTATGGAGCACCAACTGCC CTCAACCCCACCCTGTGCCCAAGACTGGGAAGGGATTGATGTCAGGCTGTGGCCATAGGT AGCATGAGTTGCCCAAGGAGGGACAGAGCATATCTTTGCTGAGGCTTGGCTGAGGGGCTT ATGATAGGGCTTGCAGTACCTCACAGCCCCCTGTGGGCACAGACACCCTGAGGTTTACCC AGGCAAATATATTGATTAGCAGGACAAGGGCTCTCTCCTCAGTTTCTGCTCCCTTCCATC TCTCTCCCATACTTGTCTGAAAAGGGAGACAAAAAATCTTATACAAGTGGCATCTCAATC CTTTCCAGTCCAGCACCTCCTGGGGCAGGCAGTGTGACTTATTTCCTGTGGTGAAATCAC CTGTTTCACAAGCCTGGCAGCGCGACTTCTGAGTCTCATGACCACTCAACCCAAGGGACC CCTCCCCAGACCAGAACCAAGTCAGCTGGGGGCTGTCGTACTACCCTGTCCAGTCTTGAG GGCCTAGTTGCAGGTCCCCCAGGCATCCAGCCCCTCCTAGAGCTTGCTGGGCAGGCTGCA CCTCATCTGGGCAGGCGCAGAGCTGATGAAATGCTGGAGCAATGCATGGCAAACATATGC CCTCCAGTGTCTTCTGAAACCTTTGGGGCTGACACAAGATCCTTTAGTGTTTGGGATGAC CTCTTTCCTGCAGACTTCTTCCCCTATCCCTAACTCATGCATGGAAAACGTTTGTCAGGC TGGTTTCCCGAGCCTCCTGCACCTCAACATCACGCTCACCCTTTTGGGTTTAGCCCAGTG TTATTTAGCAAATTTCTCCAGCTGCAGGGAAGGATCAGAGCACTATCTTTTTTTTTTTTT TTTCTCCTGGAGCCAGGACTGCACAAGGCAATGGCCAAATTTAGTTGAATTCAGCCTACC ATCCTTTGCTGATGACTCAGCTCTATGCCAAGTACTGGAGCCACAGAGATGGGTCAGTCC CAGCCCCTGTCCTCAGGAAGCCCATGGTCAGGGAAACGTTGTAGGGATAAGTAATAGAGG GCAGTTGCCTTCAGGGCTCCTGGTGGCTGCTGGTCCCTATGGTGCCTTGATGTGAATTAG AAGACGGTGCCCTTTCCAGGTGGATTCAGACCTACACTAGAACGCACAGCTTTGGGAGTG ACACACAGGTTGGATTTTAGCACCCCTTGCCCCTTGGCCAGAGGTGCCCTGCTGCACGGC CATACGCTGCAGCCTCGAGGGACACACAGGCCAAAGTGTTTCCTTCAGCCTCTTCCTGGA GAGGAAGCCGCAGGTCATGTTTCCAAGCTTCTGGTCAACTCCAGGCACCACCTCCCAGCC CCCAAACATGGCCGAGCCAGTGCTTCTCTGCAGGGCCCCTTTCCTTTCTGGAGTCAGCCT GCCCAGGTGATACCTTGAAGTGAAACTAGGGGTGGGGGAGCCTCACTAGGCCCCAGGCAC CATCCCACAGTACTGGCGGTTTCTCTGCCAAGTGTTTGGGGCCTGCACTGGCCAAGCCAT CCGTCACTGGGACTTTGCAGTGTGCCCTGTGGGTGGCGTGTGGACACCGGTCCGGGCAGG AAGGAAAAGCATGCCCCGGTGAAAACCCACCGAGCAGAGAGCCAGCGGGACCTCCTCAGC ATTCCACCCAGGGGAAGAGTTCAGTCCCCATGAAGATAAGGACTGAGTTATTTGGCTGCA CCTCTCCTCAGCCTCAAAGCTCAGACCTGCTAGAGTGGGTTCACCTGGCTGTTGGTTCTG TGGGAGAGTTCCTGACAAGCTGGTTCCTACATGGTGCAGTGAAAGGAACTCTGTCCTGGA AGTCCCCAATGCCGCCTCTCAGTCCTGCCTGTCACCAACCACCTGGGGGGCTTGGGCAAG CTACTCAACCTCTGGGGCTCAATTTCCCTAACTGTAAAATGGGATTGTAATCCCTTCCCT GCCTGACGCAGGAATTGTTATGAGGCCCAGATGAGATGAAAGTCAGCGGTCAGGGCTCTG TAAGTTGAAAATGGCTGGATGTGTGTGGCCCTGCCACTGCAGGGATGGCCCAAGGTCACA CAGAAAGTTTGCTGCAGGAGGAGCCCTCCCCACCAGTCTTCATCGCTTGCCCTGCTTCTC ACTTAGGCAGATGTCAACCAGAATGAGATACAGCCAATTTGGCTTTGATGACCCAGCTGA GAGGGAAATTTAGATACAATTCAGGAATATCATGCCCAAAAATAGTGGTCCCAGCAACCA GGACACAGAGGGAAGACCTGGATATTGTCAGTGATTGGTGGAGGGGGACATCTTGGACCC TCCTAGGCCTGGTGTCACATCTCCCATCTCTCAGACCCCACAGAGGCCAAGGGGCCTTGG CTCTGACCCAGGTTAAAGAGAGCCACCAGCCCCCAGGCTCAGGGAGCTGAAACCACCCAT CCGCAGAAATCTAAGGGCAAGGAGAAATAGAAATTGTCTGTTCCTTCCCTTCAAAGTGTA AGGCCTCTTCCAGGAGCAACTGGAGCCACCACAGCTTCTCAGTGACATTGGGAGGGCTTC GGGCCCAGGAAAAACCCAAGCCTTTTGTCCTGAGAGCCGAGCCACAGCGGATGCAGTGGC GTCAGCATCCCAGAGCGGCAGCTTCTCTCCTGCCTGTCACTGGGGACTGGTTGCTCTCCA CCCATCCAGGAGGAAGGGGTTAGGTCCCAGTCTTACACTCTTATAGGGTCTCATGGACAT AGGCCTATGCCTGTTCTGATATCTATAATTTTTTAAACTCAAAAGGACCAAAACACTCCT GAACCCTCATCTATACGGCCTGCACTGGGCTTGGTGTTTCCTCCTGGCCCAGGCAGCTCC ATCTCTTCTGCCATTCCTCCTGGACGAAAGTGGCAGGACCCCACCTCTACCACTTCCCCA CAGGGTCACTGCACAGCGGCTTCAAAGACACGCCCTGTTGAAGGGGAAACATCCTCCCCC CATCACACTCCAACTCGTCACCCCAAAAGGGAAGTCAAAGCACAGGTCCGTGGGGCCTAT GGTTTGTAGACACTGACACAGTGGTTTTCAAACCAGGTGCTGCGGAACCCCTGATATTCC ACAGAGCTTTGTCAGGGGATGCTAAAGTGGGAAGATGGGAGTGGAGGCAAAGGATAGGTT TCCAGCCCTCCTCCCATTTCCGCCGCCACCAGAATAACTCTGCTTTTATCTGTCTTGCCT ACTGAGATTTCATTTTCAAGCTTTCTTTGAAGAAGAACTTCAAACCACCATCTCGAGGTT TGATCTTAGACCAGCCAGCACAGGTTCTATTCTTGCTGTTCATGTTGGAATGGCTCCAGC GTTCCAGTACAAAGTGTCTTTGTGTTGGAACTTGGGTCACAGACCCAGGCACAAGCATTT ATACACACACACACACACACACACACACACACACACACACACGTACATAGTTGATGGTTT TTCTAGCCAACCCACCCTGAAGCTCTGGCCAAGGTTTGATTTGGACAGGGACCTGGTGCT CAGTGGGGATGGGTCGTGACCCTGATATTGGCCCATGAAGCATGGGGAGCTCTGGAGCAA GGAAACAGGCTCAATCCCCCACTGAGGACTTGTGTCTGCACCCCTATCTGGCACCCCACT TTCCTGGCCTAGGCCCAAGGGACACAGCAGGAGAAGCAGTGTGATAGGAGAGAGGCTAGG GTTAAATTCATCTTTACACAGCGCCGGATGGATGGAAATCTTGGCTCACATAAAAGACAG ACTCAGGGAGGATTTTATGACAAAAGTCCCTCCTTTGAGGGCAGGATTCCCCCAGGAATC CTGGACACTTTAGTGAGAACTGGACCAGCCCTTGGCACAAAACCCTGCCTGCCCTGTCCC CCACTCCCACCCCCCAGGGAATTCTAGGTGAAAATGTGAAGCTCAGGGCACAGCAAGCGC ATGACACGGGTGTATTACATTCGGTCCGAGTGTGTCCTTAGTTTCCCTGTGTGCAAAATG GGGCTAGTCCAGGCTCTTCCCACCTCACTGGGACAATTGCAAGGGTCATAGGAGAGGTGG GTATGATAGGTGGTCATATGAGGTGGTGAGTATGAGAGGTGGGTGCCTCACAAACTCGGG GTATGGTCCTGACCTGCATGGCAGATGAGCAGAGCACTTGGGAACGAGCATAGGAAGTGC CATCTTCCCGGGCATCTCTGCTCAGTGTTAAGGTCTAGCCACAGACACTGTGGGACCTGC CTCTTCCTATGGAATGGGGGCCTGCATGGGTTGTGTCCTGGGGCAGGAGTGAGGGATGGC TGGGAAGAATCTCCAGGTCTGTGGCCCTTGTGTTGAGTGATTATTTTGTGACACTCTCAT TCCTGGACCACCTGCCAGGTTTATCTGTTATACCTGTGGCATTCTTATTATGTCAGACAA GTTATTATAGTTCATTCAACTCTAACAAATGAACAAAAGAACAATAAATAGGAGGCCATT AAAGGTCTTTTGTGGCAGAGGAAAAAAAAAAAAAAAAAA |
Protein Sequence | >408 : length: 449 MEGDLQRERLRLHARRIQTLAFHPPQHPGAGCVALLSRVFKKASPNGKLTVYLGKRDFVD HIDLVDPVDGVVLVDPEYLKERRVYVTLTCAFRYGREDLDVLGLTFRKDLFVANVQSFPP APEDKKPLTRLQERLIKKLGEHAYPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAF CAENLEEKIHKRNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSDKPLHLEASLDKEIYY HGEPISVNVHVTNNTNKTVKKIKISVRQYADICLFNTAQYKCPVAMEEADDTVAPSSTFC KVYTLTPFLANNREKRGLALDGKLKHEDTNLASSTLLREGANREILGIIVSYKVKVKLVV SRGGLLGDLASSDVAVELPFTLMHPKPKEEPPHREVPENETPVDTNLIELDTNDDDIVFE DFARQRLKGMKDDKEEEEDGTGSPQLNNR |