Entrez Gene

Basic Information
Gene ID	3676
Name	ITGA4
Synonymous	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor);ITGA4;integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
Definition	269C wild type\|CD49 antigen-like family member D\|VLA-4 subunit alpha\|antigen CD49D, alpha-4 subunit of VLA-4 receptor\|integrin alpha 4\|integrin alpha-4\|integrin alpha-4 subunit\|integrin alpha-IV\|very late activation protein 4 receptor, alpha 4 subunit
Position	2q31.3
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
alpha4-integrin(h) + MK(h) <==> alpha4-integrin(h):MK(h) (binding)
Lrp6(m) + alpha4-integrin(h) <==> Lrp6(m):alpha4-integrin(h) (binding)
alpha4-integrin(h) + RPTPzeta(r) <==> alpha4-integrin(h):RPTPzeta(r) (binding)
alpha4-integrin(h) --> CrkL(h):c-Cbl(h){pY} (increase of binding)
alpha4-integrin(h) --> CrkL(h):HEF1(h){pY} (increase of binding)
itgb7(h) + alpha4-integrin(h) <==> itgb7(h):alpha4-integrin(h) (binding)
alpha4-integrin(h) + beta1-integrin(h) <==> alpha4-integrin(h):beta1-integrin(h) (binding)
ITGA4(h) --> alpha4-integrin(h) (expression).
paxillin-alpha(h) + alpha4-integrin(h) <==> paxillin-alpha(h):alpha4-integrin(h) (binding)
alpha4-integrin(h) + ATP --> alpha4-integrin(h){pS988} + ADP (phosphorylation)
alpha4-integrin(h) --> Pyk2(h){pY} (increase of phosphorylation)
ITGA4(h) --> alpha4-integrin(h) (expression).

Location (AA)	PTM type	Database
Post Translational Modification [Top]
85	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
144	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
235	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
486	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
524	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
544	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
632	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
651	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
666	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
812	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
827	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
1027	Phosphoserine.	Swiss-Prot 53.0

Transcription Factors [Top]