| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3673 |
Name | ITGA2 |
Synonymous | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor);ITGA2;integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
Definition | CD49 antigen-like family member B|VLA2 receptor, alpha-2 subunit|collagen receptor|human platelet alloantigen system 5|integrin alpha-2|platelet antigen Br|platelet glycoprotein GPIa|platelet membrane glycoprotein Ia|very late activation protein 2 recepto |
Position | 5q11.2 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | VLA-2(h) --> RhoA(h) (activation) | ITGA2(h) --> VLA-2(h) (expression). | aup-1-isoformS(h) + VLA-2(h) <==> aup-1-isoformS(h):VLA-2(h) (binding) | ITGA2(h) --> VLA-2(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 105 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 112 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 343 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 432 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 460 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 475 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 699 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 1057 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 1074 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 1081 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr5 |
Promoter: 52319413 - 52321413 | Agilent_014791 |
chr5 |
Promoter: 52319413 - 52321413 | GoldenGate_Methylation_Cancer_Panel_I |
chr5 |
Promoter: 52319413 - 52321413 | GSE27584 |
chr5 |
Promoter: 52319413 - 52321413 | Agilent_014791_44K |