| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3190 |
Name | HNRNPK |
Synonymous | heterogeneous nuclear ribonucleoprotein K;HNRNPK;heterogeneous nuclear ribonucleoprotein K |
Definition | dC-stretch binding protein|transformation upregulated nuclear protein |
Position | 9q21.32-q21.33 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | hnRNPK(h) --> c-myc(h) (DNA binding; transregulation). | hnRNPK(h) + Vav(h) <==> hnRNPK(h):Vav(h) (binding) | hnRNPK(h) + HCV-core-1B-Taiwan(HCV1BTAI) <==> hnRNPK(h):HCV-core-1B-Taiwan(HCV1BTAI) (binding) | HCV-core(HCV) + hnRNPK(h) <==> HCV-core(HCV):hnRNPK(h) (binding) | PITK(h) + hnRNPK(h) <==> PITK(h):hnRNPK(h) (binding) | hnRNPK(h) + ATP --> hnRNPK(h){p} + ADP (phosphorylation) | Vav(h){pY} + hnRNPK(h) <==> Vav(h){pY}:hnRNPK(h) (binding) | hnRNPK(h) + ATP --> hnRNPK(h){pY} + ADP (phosphorylation) | Src(h) + hnRNPK(h) <==> Src(h):hnRNPK(h) (binding) | hnRNPK(h) --> EIF4E(h) (DNA binding). | hnRNPK(h) --> SRC(h) (DNA binding). | 2 hnRNPK(h) <==> (hnRNPK(h))2 (binding) | hnRNPK(h) + Ubc9(h) <==> hnRNPK(h):Ubc9(h) (binding) | hnRNPK(h) + Nck-2(h) <==> hnRNPK(h):Nck-2(h) (binding) | hnRNPK(h) + Grap2(h) <==> hnRNPK(h):Grap2(h) (binding) | hnRNPK(h) + QK1(h) <==> hnRNPK(h):QK1(h) (binding) | hnRNPK(h) + Matrin-3(h) <==> hnRNPK(h):Matrin-3(h) (binding) | hnRNPK(h) + Vinexin(h) <==> hnRNPK(h):Vinexin(h) (binding) | hnRNPK(h) + Rbm7(h) <==> hnRNPK(h):Rbm7(h) (binding) | hnRNPK(h) + SLM2(h) <==> hnRNPK(h):SLM2(h) (binding) | hnRNPK(h) + cyclinM3(h) <==> hnRNPK(h):cyclinM3(h) (binding) | hnRNPK(h) + hnRNP-G(h) <==> hnRNPK(h):hnRNP-G(h) (binding) | hnRNPK(h) + rbm41(h) <==> hnRNPK(h):rbm41(h) (binding) | hnRNPK(h) + NPDC1(h) <==> hnRNPK(h):NPDC1(h) (binding) | hnRNPK(h) + rbm42(h) <==> hnRNPK(h):rbm42(h) (binding) | hnRNPK(h) + SLM-1(h) <==> hnRNPK(h):SLM-1(h) (binding) | hnRNPK(h) + MO15(h) <==> hnRNPK(h):MO15(h) (binding) | hnRNPK(h) + TRAP170(h) <==> hnRNPK(h):TRAP170(h) (binding) | hnRNPK(h) --> LDLR(h) (DNA binding; transactivation). | HNRPK(h) --> hnRNPK(h) (expression). | HNRPK(h) --> hnRNPK-isoform1(h) (expression). | HNRPK(h) --> hnRNPK-isoform2(h) (expression). | HNRPK(h) --> hnRNPK-isoform3(h) (expression). |
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Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 3 | Phosphothreonine. | Swiss-Prot 53.0 | 36 | Phosphoserine. | Swiss-Prot 53.0 | 116 | Phosphoserine. | Swiss-Prot 53.0 | 216 | Phosphoserine. | Swiss-Prot 53.0 | 284 | Phosphoserine. | Swiss-Prot 53.0 | 296 | Omega-N-methylated arginine. | Swiss-Prot 53.0 | 299 | Omega-N-methylated arginine. | Swiss-Prot 53.0 | 379 | Phosphoserine. | Swiss-Prot 53.0 | 302 | Phosphoserine (PKC delta) | 10329716 | Phospho.ELM 6.0 | 216 | Phosphoserine (MAPK10) | 11259409;17081983 | Phospho.ELM 6.0 | 284 | Phosphoserine (MAPK10;PKC d) | 10329716;11259409;15302935;16083285;17081983 | Phospho.ELM 6.0 | 353 | Phosphoserine (MAPK10;MAPK3) | 11259409;11231586 | Phospho.ELM 6.0 | 3 | Phosphothreonine | 15302935 | Phospho.ELM 6.0 | 116 | Phosphoserine | 15302935 | Phospho.ELM 6.0 | 36 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 230 | Phosphotyrosine (Src) | 12052863 | Phospho.ELM 6.0 | 234 | Phosphotyrosine (Src) | 12052863 | Phospho.ELM 6.0 | 236 | Phosphotyrosine (Src) | 12052863 | Phospho.ELM 6.0 | 380 | Phosphotyrosine (Src) | 12052863 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr9 |
Promoter: 85784402 - 85786402 | GSE27584 |
chr9 |
Promoter: 85784839 - 85786839 | GSE27584 |
chr9 |
Promoter: 85784839 - 85786839 | GSE27584 |
chr9 |
Promoter: 85784839 - 85786839 | Agilent_014791_44K |