Entrez Gene

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Basic Information
Gene ID	2886
Name	GRB7
Synonymous	growth factor receptor-bound protein 7;GRB7;growth factor receptor-bound protein 7
Definition	B47\|GRB7 adapter protein\|epidermal growth factor receptor GRB-7
Position	17q12
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
c-Kit(h){pY936} + Grb-7(h) <==> c-Kit(h){pY936}:Grb-7(h) (binding)
ErbB3(h){pY1180} + Grb-7(h) <==> ErbB3(h){pY1180}:Grb-7(h) (binding)
ErbB3(h){pY1243} + Grb-7(h) <==> ErbB3(h){pY1243}:Grb-7(h) (binding)
ErbB2(h){pY1180} + Grb-7(h) <==> ErbB2(h){pY1180}:Grb-7(h) (binding)
ErbB2(h){pY1243} + Grb-7(h) <==> ErbB2(h){pY1243}:Grb-7(h) (binding)
ErbB2(h){pY1139} + Grb-7(h) <==> ErbB2(h){pY1139}:Grb-7(h) (binding)
InsR(h){p} + Grb-7(h) <==> InsR(h){p}:Grb-7(h) (binding)
ErbB1-p170(h){pY1016}{pY1172} + Grb-7(h) <==> Grb-7(h):ErbB1-p170(h){pY1016}{pY1172} (binding)
ErbB2(h){pY1221} + Grb-7(h) <==> ErbB2(h){pY1221}:Grb-7(h) (binding)
Grb-7(h) + ErbB3-isoform1(h){pY1197}{pY1260}{pY1276}{pY1289} <==> Grb-7(h):ErbB3-isoform1(h){pY1197}{pY1260}{pY1276}{pY1289} (binding)
ErbB4(h){pY1258} + Grb-7(h) <==> ErbB4(h){pY1258}:Grb-7(h) (binding)
14-3-3sigma(m.s.) + Grb-7(h) <==> 14-3-3sigma(m.s.):Grb-7(h) (binding)
GRB7(h) --> Grb-7(h) (expression).
GRB7(h) --> Grb7-isoform1(h) (expression).
GRB7(h) --> Grb7-isoform2(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Translational Modification [Top]
366	Phosphoserine (By similarity).		Swiss-Prot 53.0

Chromosome	Location	Source
Methylation Profile [Top]
chr17	Promoter: 35146616 - 35148616	GoldenGate_Methylation_Cancer_Panel_I
chr17	Promoter: 35146213 - 35148213	GoldenGate_Methylation_Cancer_Panel_I
chr17	Promoter: 35146616 - 35148616	GSE27584
chr17	Promoter: 35146213 - 35148213	GSE27584